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Listar por autor "Molina-Santiago, Carlos"
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Bacillus extracellular matrix modulates Botrytis metabolism and growth
Pérez-Lorente, Alicia; Molina-Santiago, Carlos; Vela-Corcía, David; Stincone, P; De-Vicente-Moreno, Antonio; Petras, Daniel; Romero-Hinojosa, Diego Francisco[et al.] (2023)In nature, bacteria often form communities known as biofilms, where cells are embedded in a self-produced extracellular matrix (ECM) that provides protection against external aggressions or facilitates efficient use of ... -
BacLive, una innovadora herramienta para el estudio de dinámica de poblaciones e interacciones microbianas
Pérez-Lorente, Alicia; Molina-Santiago, Carlos; Pearson, John R.; Berlanga-Clavero, María Victoria; De-Vicente-Moreno, Antonio; Romero-Hinojosa, Diego Francisco[et al.] (2021)En la naturaleza, las bacterias se encuentran frecuentemente formando comunidades bacterianas conocidas como biofilms. Las interacciones inter o intra-específicas pueden alterar notablemente la estructura de la comunidad ... -
Chemical interplay and complementary adaptative strategies toggle bacterial antagonism and co-existence.
Molina-Santiago, Carlos; Vela-Corcía, David; Petras, Daniel; Diaz-Martínez, Luis; Pérez-Lorente, Alicia Isabel; Sopeña-Torres, Sara; Pearson, John; Caraballo-Rodríguez, Andrés Mauricio; Dorrestein, Pieter; de Vicente, Antonio; Romero, Diego[et al.] (Cell Press, 2021-07-27)Bacterial communities are in a continuous adaptive and evolutionary race for survival. In this work we expand our knowledge on the chemical interplay and specific mutations that modulate the transition from antagonism to ... -
Deciphering the chemical dialogue between Bacillus and pathogenic fungi.
Pérez-Lorente, Alicia Isabel; Molina-Santiago, Carlos; Vela, David; Stincone, Paolo; Pakkir Shah, Abzer K.; De-Vicente-Moreno, Antonio; Petras, Daniel; Romero-Hinojosa, Diego Francisco[et al.] (2024)In nature, bacteria frequently form bacterial communities known as biofilms, where cells are embedded within an extracellular matrix (ECM) that provides protection against external aggressions or facilitates the efficient ... -
Differential transcriptional response to antibiotics by Pseudomonas putida DOT-T1E
Molina-Santiago, Carlos; Daddaoua, Abdelali; Gómez-Lozano, María; Udaondo, Zulema; Molin, Soren; Ramos, Juan-Luis[et al.] (Wiley, 2015)Multi-drug resistant bacteria are a major threat to humanity, especially because the current battery of known antibiotics is not sufficient to combat infections produced by these microbes. Therefore, the study of how current ... -
Efflux pump-deficient mutants as a platform to search for microbes that produce antibiotics
Molina-Santiago, Carlos; Udaondo, Zulema; Daddaoua, Abdelali; Roca, Amalia; Martín, Jesús; Pérez-Victoria, Ignacio; Reyes, Fernando; Ramos, Juan Luis[et al.] (Wiley, 2015-01-08)Pseudomonas putida DOT-T1E-18 is a strain deficient in the major antibiotic efflux pump (TtgABC) that exhibits an overall increased susceptibility to a wide range of drugs when compared with the wild-type strain. We used ... -
El papel dual del amiloide funcional TasA del biofilm de Bacillus subtilis en la fisiología bacteriana y la persistencia sobre la superficie de la planta
Cámara-Almirón, Jesús; Navarro, Yurena; Magno, M. Concepción; Molina-Santiago, Carlos; De-Vicente-Moreno, Antonio; Pérez-García, Alejandro; Romero-Hinojosa, Diego Francisco[et al.] (2019-02-08)Los biofilms son comunidades bacterianas complejas formadas en cualquier superficie y compuestas de células embebidas en una matriz extracelular. Esta estructura bacteriana dE B. subitlis está compuesta de exopolisacáridos ... -
Estudio en Bacillus subtilis de la resistencia a antibióticos mediada por GlpK
Molina-Santiago, Carlos; Vela-Corcía, David; Díaz-Martínez, Luis; De-Vicente-Moreno, Antonio; Romero-Hinojosa, Diego Francisco (2021)El aumento de bacterias multi-resistentes a antibióticos es un problema a nivel mundial que provocará más de 10 millones de muertes al año en 2050 según la OMS. Por tanto, es prioritario comprender cómo las bacterias ... -
Extracellular matrix components are required to protect bacillus subtilis from pseudomonas invasion and co-colonization of plants
Pearson, John R.; Molina-Santiago, Carlos; De-Vicente-Moreno, Antonio; Romero-Hinojosa, Diego Francisco (2018-12-13)Plants are colonized by a vast variety of microbes. Among them, bacteria are the most predominant and are able to adapt to environmental changes and interact with other microorganisms using a wide array of molecules, ... -
Fathoming the interaction between secondary metabolites of phylogenetically related Bacillus species and the plant metabolome.
Carrégalo Ríos, María Luisa; Molina-Santiago, Carlos; Berlanga-Clavero, María Victoria; Pineda-Dorado, M.; Barón Ayala, M.; Dorrestein, Pieter; De-Vicente-Moreno, Antonio; Romero-Hinojosa, Diego Francisco[et al.] (2024)Plant-beneficial microbes are known to provide multifaceted traits that contribute to plant health. Bacillus species, frequently found within the plant holobiont, are known to enhance seed germination, promote plant growth, ... -
Fengicina y la proteína amiloide TasA de Bacillus subtilis estimulan el crecimiento y la inmunización de las plantas actuando sobre reservas de la semilla
Berlanga-Clavero, María Victoria; Molina-Santiago, Carlos; Díaz-Martínez, Luis; Pérez-García, Alejandro; De-Vicente-Moreno, Antonio; Romero-Hinojosa, Diego Francisco[et al.] (2022)Bacillus subtilis es una bacteria comúnmente utilizada en estrategias agrícolas sostenibles ya que establece relaciones mutualistas con plantas. Su contribución beneficiosa es multifactorial, por lo que definir los factores ... -
Fengycin and the amyloid TasA of Bacillus subtilis stimulates the growth and immunization of plants by targeting the seed storages
Berlanga-Clavero, María Victoria; Molina-Santiago, Carlos; Díaz-Martínez, Luis; Pérez-García, Alejandro; De-Vicente-Moreno, Antonio; Romero-Hinojosa, Diego Francisco[et al.] (2022)Beneficial microbes are known to stimulate the germination of the seeds; however, the exact mechanisms mediating these interactions are only beginning. Bacillus subtilis is a commonly detected member of the plant holobiont ... -
Fengycin and the amyloid TasA of Bacillus subtilis stimulates the growth and immunization of plants by targeting the seed storages
Berlanga-Clavero, María Victoria; Molina-Santiago, Carlos; Caraballo-Rodríguez, Andrés Mauricio; Petras, Daniel; Díaz-Martínez, Luis; Pérez-García, Alejandro; De-Vicente-Moreno, Antonio; Carrión Bravo, Víctor José; Dorrestein, Pieter; Romero, D.[et al.] (2022)Beneficial microbes are known to stimulate the germination of the seeds; however, the exact mechanisms mediating these interactions are only beginning. Bacillus subtilis is a commonly detected member of the plant holobiont ... -
From bacterial antagonism to co-existence: the chemical interplay and adaptative strategies between Pseudomonas and Bacillus
Molina-Santiago, Carlos; Vela-Corcía, David; Petras, Daniel; Díaz-Martínez, Luis; Pérez-Lorente, Alicia; Pearson, John R.; Caraballo-Rodríguez, Andrés Mauricio; Dorrestein, Pieter; De-Vicente-Moreno, Antonio; Romero-Hinojosa, Diego Francisco[et al.] (2022)Bacterial communities are continuously adapting and evolving for survival. They produce and secrete a broad range of molecules that kill, defend, or mediate communication between cells of different lineages, thus shaping ... -
Genetically engineering Pseudomonas strains for T6SS-dependent controlled release of effectors.
Araujo-Garrido, Mario; Pérez-Lorente, Alicia Isabel; Romero-Hinojosa, Diego Francisco; Molina-Santiago, Carlos (2024)Type VI secretion systems (T6SS) are Gram-negative bacteria’s syringe-like nanomachine that injects effectors into prokaryotic and eukaryotic cells leading to the death of their target. These systems have the potential ... -
Implicación de la matriz extracelular de Bacillus subtilis en la interacción beneficiosa con la planta
Berlanga-Clavero, María Victoria; Molina-Santiago, Carlos; Navarro, Yurena; Cámara-Almirón, Jesús; Sopeña, Sara; Blasco-Santamaría, María Luz; Pérez-García, Alejandro; De-Vicente-Moreno, Antonio; Romero-Hinojosa, Diego Francisco[et al.] (2019-02-08)Bacillus subtilis es una bacteria Gram-positiva comúnmente presente en los suelos. Algunos aislados de esta especie son capaces de promover el crecimiento en plantas (actividad PGPR, del inglés plant growth promoting ... -
Interspecies signalling: Pseudomonas putida efflux pump TtgGHI is activated by indole to increase antibiotic resistance
Molina-Santiago, Carlos; Daddaoua, Abdelali; Fillet, Sandy; Duque, Estrella; Ramos, Juan Luis (Wiley, 2013-12-14)In Gram-negative bacteria, multidrug efflux pumps are responsible for the extrusion of chemicals that are deleterious for growth. Some of these efflux pumps are induced by endogenously produced effectors, while abiotic or ... -
Los componentes de la matriz extracelular de Bacillus subtilis son necesarios para proteger la colonia de la invasión de Pseudomonas y para la co-colonización en plantas
Molina-Santiago, Carlos; Pearson, John R.; Navarro, Yurena; Berlanga-Clavero, María Victoria; Petras, Daniel; Caraballo-Rodríguez, Andrés Mauricio; De-Vicente-Moreno, Antonio; Dorrestein, Pieter; Romero-Hinojosa, Diego Francisco[et al.] (2019-02-08)Las plantas son colonizadas por una gran variedad de microorganismos, y entre ellas las bacterias son las más predominantes dada su capacidad para adaptarse a cambios ambientales y comunicarse con otros organismos. La ... -
Molecular mechanisms and ecological significance of the Bacillus subtilis extracellular matrix in the mutualism with plants
Berlanga-Clavero, María Victoria (UMA Editorial, 2024)La introducción de la agricultura ha tenido un impacto significativo en la humanidad, permitiendo el establecimiento de poblaciones y garantizando un suministro estable de alimentos. En la actualidad, con una población en ... -
Overtake, resilience and escape: three ecological strategies that define the Pseudomonas-Bacillus interactions
Plants are colonized by a vast variety of microbes, some of which promote plant growth and protection against pathogens. One way bacteria have evolved to succeed in this competitive scenario is the formation of biofilms ...