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IIIG9 inhibition in adult ependymal cells changes adherens junctions structure and induces cellular detachment.
Baeza, Víctor; Cifuentes-Rueda, Manuel; Martínez, Fernando; Ramírez, Eder; Nualart, Francisco; Ferrada, Luciano; Oviedo, María José; De Lima, Isabelle; Troncoso, Ninoschka; Saldivia, Natalia; Salazar, Katty[et al.] (Springer Nature, 2021)
Ependymal cells have multiple apical cilia that line the ventricular surfaces and the central canal of spinal cord. In cancer, the loss of ependymal cell polarity promotes the formation of different types of tumors, such ...