Listar por autor "Gémez Mata, Juan"
Mostrando ítems 1-20 de 26
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Actividad antagonista de aislados del Virus de la Septicemia Hemorrágica Viral (VHSV) frente al sistema del interferón tipo I de lenguado senegalés
Gémez-Mata, Juan; Álvarez-Torres, Daniel; García-Rosado, Esther
; Alonso-Sánchez, María del Carmen; Béjar-Alvarado, Julia (2017-10-11)
Senegalese sole (Solea senegalensis) is susceptible to marine Viral Haemorrhagic Septicaemia Virus (VHSV) isolates, but it is not affected by freshwater VHSV isolates. In addition, the sole type I interferon (IFN I) response ... -
Análisis de la expresión de inmunogenes en doradas vacunadas en respuesta a la infección por LCDV-Sa
Leiva-Rebollo, Rocío; Gémez-Mata, Juan; Labella Vera, Alejandro Manuel; Castro-López, María Dolores; Borrego-García, Juan José (2021)
El objetivo del presente estudio ha sido evaluar la respuesta inmune frente a la infección por Lymphocystis Disease Virus 3 (LCDV-Sa) en ejemplares de dorada (Sparus aurata) vacunados con un plásmido que codifica la proteína ... -
Analysis of gene expression in nodavirus-inoculated Senegalese sole using a new Openarray® platform.
Labella Vera, Alejandro Manuel; Gémez Mata, Juan; Vera, Isabel; Bandin, Isabel; Leiva Rebollo, Rocío; Borrego-García, Juan José; García-Rosado, Esther[et al.] (Elsevier, 2019)
Nervous necrosis virus (NNV) is the causative agent of the viral encephalopathy and retinopathy, a disease that affects cultured Senegalese sole (Solea senegalensis). A NNV reassortant (Ss160.03), combining genomic segments ... -
Differential immunogene expression profile of European sea bass (Dicentrarchus labrax, L.) in response to highly and low virulent NN
Moreno, Patricia; Gémez-Mata, Juan; García-Rosado, Esther; Béjar-Alvarado, Julia; Labella Vera, Alejandro Manuel; Souto, Sandra; Alonso-Sánchez, María del Carmen[et al.] (Elsevier, 2020)
European sea bass is highly susceptible to the nervous necrosis virus, RGNNV genotype, whereas natural outbreaks caused by the SJNNV genotype have not been recorded. The onset and severity of an infectious disease depend ... -
Estudio in vitro de la actividad antagonista de aislados del virus de la septicemia hemorrágica viral (VHSV) de distinto origen sobre el sistema del IFN tipo I
Gémez-Mata, Juan; Álvarez-Torres, Daniel; Alonso-Sánchez, María del Carmen; García-Rosado, Esther; Béjar-Alvarado, Julia (2018-11-09)
El lenguado senegalés (Solea senegalensis) es susceptible a aislados marinos del virus de la septicemia hemorrágica viral (VHSV); sin embargo, los VHSV patógenos para especies de agua dulce no son virulentos para especies ... -
European sea bass RTP3 genes: genomic characterization and transcription analyses.
Moreno-García, Patricia; Gémez-Mata, Juan; Álvarez-Torres, Daniel; García-Rosado, Esther; Béjar-Alvarado, Julia; Alonso-Sánchez, María del Carmen[et al.] (2023)
Introduction: Fish RTP3, belonging to receptor-transporting protein (RTP) family, has been described as an interferon-α (IFN-α)-responsive gene. However, little information is available about fish rtp3 gene structure and ... -
Evaluación de la respuesta inmune en doradas tras la administración de una vacuna inactivada frente a betanodavirus
Gémez-Mata, Juan; Leiva-Rebollo, Rocío; Moreno, Patricia; Borrego-García, Juan José; García-Rosado, Esther; Labella Vera, Alejandro Manuel; Castro-López, María Dolores[et al.] (2023)
El virus de la necrosis nerviosa (VNN), género Betanodavirus, familia Nodaviridae, es el agente etiológico de la necrosis nerviosa viral, enfermedad que afecta a peces cultivados en todo el mundo. Existen cuatro especies ... -
Evaluación de la respuesta inmune en lenguado senegalés conferida por una vacuna inactivada frente a Betanodavirus
Gémez-Mata, Juan; Leiva-Rebollo, Rocío; López-Vázquez, Carmen; Olveira, José G.; Bandín Matos, Isabel; Borrego-García, Juan José; Castro-López, María Dolores; Labella Vera, Alejandro Manuel[et al.] (2022)
La necrosis nerviosa viral es una enfermedad que afecta a peces cultivados en todo el mundo. Su agente etiológico es el virus de la necrosis nerviosa, género Betanodavirus, familia Nodaviridae, que presenta un genoma ... -
Evaluation of immune response after LCDV-Sa infection in DNA-vaccinated gilthead seabream
Leiva-Rebollo, Rocío; Gémez-Mata, Juan; Castro-López, María Dolores; Borrego-García, Juan José; Labella Vera, Alejandro Manuel (2021)
The immune-related gene expression in vaccinated gilthead seabream after Lymphocystis Disease Virus 3 (LCDV-Sa) infection was analysed by using an OpenArray based on TaqMan qPCR. The DNA vaccine used in this study encodes ... -
Evaluation of the immune response in betanodavirus-vaccinated gilthead seabream.
Gémez-Mata, Juan; Leiva-Rebollo, Rocío; Moreno-García, Patricia; Bandín Matos, Isabel; Borrego-García, Juan José; Labella Vera, Alejandro Manuel; Castro-López, María Dolores[et al.] (2023)
An inactivated vaccine has been developed using a RGNNV/SJNNV reassortant strain isolated from Senegalese sole, which confers moderate protection against the homologous viral strain in sole juveniles. The aim of this study ... -
Fish Iridoviridae: infection, vaccination and immune response
Leiva Rebollo, Rocío; Labella Vera, Alejandro Manuel; Gémez Mata, Juan; Castro-López, María Dolores; Borrego García, Juan José (Springer Nature, 2024-07-15)
Each year, due to climate change, an increasing number of new pathogens are being discovered and studied, leading to an increase in the number of known diseases affecting various fish species in different regions of the ... -
Genomic characterization and transcription analysis of European sea bass (Dicentrarchus labrax) rtp3 genes
Moreno-García, Patricia; Gémez-Mata, Juan; Álvarez-Torres, Daniel; García-Rosado, Esther; Béjar-Alvarado, Julia; Alonso-Sánchez, María del Carmen[et al.] (Elsevier, 2023-10-23)
Fish RTP3, belonging to the receptor-transporting protein family, display several functions, including a putative antiviral role as virus-responsive gene. In this work, we have identified and characterized two different ... -
Genomic characterization and transcription analysis of European sea bass (Dicentrarchus labrax) rtp3 genes.
Moreno, Patricia; Gémez-Mata, Juan; Álvarez-Torres, Daniel; García-Rosado, Esther; Béjar-Alvarado, Julia; Alonso-Sánchez, María del Carmen[et al.] (Elsevier, 2023-10-23)
Fish RTP3, belonging to the receptor-transporting protein family, display several functions, including a putative antiviral role as virus-responsive gene. In this work, we have identified and characterized two different ... -
Immune gene expression in gilthead seabream after nervous necrosis virus (NNV) challenge
Gémez-Mata, Juan; Leiva-Rebollo, Rocío; Moreno-García, Patricia; Bandín Matos, Isabel; Borrego-García, Juan José; Labella Vera, Alejandro Manuel; Castro-López, María Dolores[et al.] (2022-09)
Viral nervous necrosis (VNN) is a disease that affects farmed fish worldwide. Its etiologic agent is the nervous necrosis virus (NNV), genus Betanodavirus, family Nodaviridae. NNV are small and non-enveloped viruses with ... -
Immune response of DNA vaccinated-gilthead seabream (Sparus aurata) against LCDV-Sa infection: relevance of the inflammatory process
Leiva Rebollo, Rocío; Gémez Mata, Juan; Castro-López, María Dolores; Borrego García, Juan José; Labella Vera, Alejandro Manuel (Frontiers, 2023-06-06)
Lymphocystis disease is one of the main viral pathologies affecting cultured gilthead seabream (Sparus aurata) in the Mediterranean region. Recently, we have developed a DNA vaccine based on the major capsid protein (MCP) ... -
Immune response of DNA vaccinated-gilthead seabream against LCDV-Sa infection: relevance of the inflammatory process.
Leiva-Rebollo, Rocío; Gémez-Mata, Juan; Castro-López, María Dolores; Borrego-García, Juan José; Labella Vera, Alejandro Manuel (2023)
Lymphocystis disease is one of the main viral pathologies affecting cultured gilthead seabream in the Mediterranean area. Recently, we have developed a DNA-vaccine based on the major capsid protein of the Lymphocystis ... -
Immune response of gilthead seabream infected with wild and mutant nervous necrosis virus reassortants.
Gémez-Mata, Juan; Leiva-Rebollo, Rocío; Moreno-García, Patricia; Borrego-García, Juan José; Labella Vera, Alejandro Manuel; Castro-López, María Dolores[et al.] (2023)
Viral nervous necrosis (VNN) is a disease that affects farmed fish worldwide. Its etiologic agent is the nervous necrosis virus currently classified into 4 species: SJNNV, RGNNV, TPNNV and BFNNV. In Southern Europe, ... -
Immune Response of Senegalese Sole against Betanodavirus Mutants with Modified Virulence.
Gémez Mata, Juan; Souto, Sandra; Bandin, Isabel; Alonso-Sánchez, María del Carmen; Borrego-García, Juan José; Labella Vera, Alejandro Manuel; García-Rosado, Esther[et al.] (MDPI, 2021-10-27)
Nervous necrosis virus (NNV), genus Betanodavirus, the etiological agent of the viral encephalopathy and retinopathy (VER), presents a genome with two positive-sense single-stranded RNA segments. Striped jack nervous ... -
Immune response of Senegalese sole and gilthead seabream after vaccination with an inactivated vaccine against betanodavirus.
Gémez-Mata, Juan; Leiva-Rebollo, Rocío; Moreno-García, Patricia; Bandín Matos, Isabel; Borrego-García, Juan José; Labella Vera, Alejandro Manuel; Castro-López, María Dolores[et al.] (2024)
Nervous necrosis virus (NNV) (genus Betanodavirus, family Nodaviridae) is the etiologic agent of viral encephalopathy and retinopathy (VER). This virus is classified into four species: SJNNV, RGNNV, TPNNV and BFNNV. In ... -
Immune response of vaccinated juvenile gilthead seabream (Sparus aurata) after LCDV-Sa infection
Leiva-Rebollo, Rocío; Gémez-Mata, Juan; Borrego-García, Juan José; Castro-López, María Dolores; Labella Vera, Alejandro Manuel (2022-09)
Lymphocystis disease is one of the main viral pathologies affecting cultured gilthead seabream in the Mediterranean area. In our group, a DNA-vaccine has been developed based on the major capsid protein (MCP) of the ...