Listar por autor "Morales, Rodrigo"
Mostrando ítems 1-12 de 12
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Aggregate-Depleted Brain Fails to Induce Ab Deposition in a Mouse Model of Alzheimer’s Disease.
(PLOS, 2014-02-12)Recent studies in animal models of Alzheimer’s disease (AD) show that amyloid-beta (Ab) misfolding can be transmissible; however, the mechanisms by which this process occurs have not been fully explored. The goal of this ... -
Brains from non-Alzheimer’s individuals containing amyloid deposits accelerate Aβ deposition in vivo.
(BMC, 2013-11-18)Background: One of the main features of Alzheimer’s disease (AD) is the presence of Aβ deposits, which accumulate in the brain years before the onset of symptoms. We and others have demonstrated that cerebral Aβ-amyloidosis ... -
Dataset seeding paper JAL.
Andreo-López, Juana; Núñez-Díaz, Cristina; Do Huynh, Kelly; Minh Thu Nguyen, Marie; Da Cunha, Celia; Cantero-Molina, Francisco; Campos-Moreno, Cynthia; Zimbone, Stefania; Bellia, Francesco; Giuffrida, Maria Laura; Trujillo-Estrada, Laura Isabel
; García-León, Juan Antonio; Bettinetti-Luque, Miriam; Gámez, Nazaret; Valdés, Catalina; Morales, Rodrigo; Forner, Stefania; Martini, Alessandra C.; Gutiérrez-Pérez, Antonia; LaFerla, Frank; Baglietto-Vargas, David[et al.] (Universidad de Málaga, 2023-11-24)
Este trabajo se centra en el estudio de la propagación de la patología amiloidea en diferentes modelos animales para la Enfermedad de Alzheimer (EA). Los resultados sugieren que existen diversos factores que modulan este ... -
EARMO: An Energy-Aware Refactoring Approach for Mobile Apps
(IEEE, 2017)The energy consumption of mobile apps is a trending topic and researchers are actively investigating the role of coding practices on energy consumption. Recent studies suggest that design choices can conflict with energy ... -
EARMO: An Energy-Aware Refactoring Approach for Mobile Apps
Morales, Rodrigo; Saborido Infantes, Rubén; Khomh, Foutse; Chicano-García, José-Francisco; Antoniol, Giuliano (IEEE, 2018)
The energy consumption of mobile apps is a trending topic and researchers are actively investigating the role of coding practices on energy consumption. Recent studies suggest that design choices can conflict with energy ... -
Getting the most from map data structures in Android
(Springer, 2018)A map is a data structure that is commonly used to store data as key–value pairs and retrieve data as keys, values, or key–value pairs. Although Java offers different map implementation classes, Android SDK offers other ... -
Human and Mouse Alzheimer's Seeds Differentially Affect Amyloid Deposition and Microglia-Dependent Plaque Response in Aged Mice
Andreo-López, Juana; Núñez-Díaz, Cristina; Do Huynh, Kelly; Minh Thu Nguyen, Marie; Da Cunha, Celia; Cantero-Molina, Francisco; Campos-Moreno, Cynthia; Zimbone, Stefania; Bellia, Francesco; Giuffrida, Maria Laura; Trujillo-Estrada, Laura Isabel; García-León, Juan Antonio; Bettinetti-Luque, Miriam; Gámez, Nazaret; Valdés, Catalina; Morales, Rodrigo; Forner, Stefania; Martini, Alessandra C.; Gutiérrez-Pérez, Antonia; LaFerla, Frank M.; Baglietto-Vargas, David[et al.] (Wiley, 2025-05-13)
Alzheimer's disease (AD) is a complex neurodegenerative proteinopathy in which Aβ and tau misfold and aggregate into entities that structurally unsettle native proteins, mimicking a prion-like or “seeding” process. These ... -
MoMIT: Porting a JavaScript Interpreter on a Quarter Coin
(IEEE (Institute of Electrical and Electronics Engineers), 2020)The Internet of Things (IoT) is a network of physical, connected devices providing services through private networks and the Internet. The devices connect through the Internet to Web servers and other devices. One of the ... -
Peripheral delivery of neural precursor cells ameliorates parkinson’s disease-associated pathology
(MDPI, 2019)Parkinson’s disease (PD) is a progressive neurodegenerative disorder characterized by loss of motor control due to a wide loss of dopaminergic neurons along the nigro-striatal pathway. Some of the mechanisms that contribute ... -
The Endoplasmic Reticulum Chaperone GRP78/BiP Modulates Prion Propagation in vitro and in vivo
(Springer Nature, 2017)Prion diseases are fatal neurodegenerative disorders affecting several mammalian species, characterized by the accumulation of the misfolded form of the prion protein, which is followed by the induction of endoplasmic ... -
Treatment with a non-toxic, self-replicating anti-prion delays or prevents prion disease in vivo.
(Springer Nature, 2018)Transmissible spongiform encephalopathies (TSEs) are fatal neurological disorders caused by prions, which are composed of a misfolded protein (PrP Sc) that self-propagates in the brain of infected individuals by converting ...