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Listar por autor "Bernal Muñoz, Manuel"
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Nuclear and mitochondrial homologous recombination process to repair DSB by nucleases and helicases
Bernal Muñoz, Manuel (2019-01-25)Cells are continuously exposed to different sources of DNA damage agents that can compromise genome stability. Double-strand break (DSB) is one of the most cytotoxic lesions, so faithful repair of DSB is critical to ensure ... -
The synthetic molecule stauprimide impairs cell growth and migration in triple-negative breast cancer
Carrillo Fernández, Paloma; Bernal Muñoz, Manuel; Téllez Quijorna, Clara; Marrero Capitán, Ana Dácil; Vidal-Valenzuela, Isabel; Castilla, Laura; Caro Salazar, Carlos; Domínguez Moreno, Alejandro; García-Martín, María Luisa; Rodríguez-Quesada, Ana María; Medina-Torres, Miguel Ángel
; Martínez-Póveda, Beatriz Amparo
[et al.] (Elsevier, 2022-12-14)
Stauprimide, a semi-synthetic derivative of staurosporine, is known mainly for its potent differentiation-enhancing properties in embryonic stem cells. Here, we studied the effects of stauprimide in cell growth and migration ...