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Listar por autor "van Veen, Michiel"
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GDE2/GDPD5 in neuroblastoma
Matas-Rico, Elisa; van Veen, Michiel; Moolenaar, Wouter H (Impact Journals, 2017-01)No abstract available -
Glycerophosphodiesterase GDE2/GDPD5 affects pancreas differentiation in zebrafish
van Veen, Michiel; Mans, Laurie A; Matas-Rico, Elisa; van Pelt, Jason; Perrakis, Anastassis; Moolenaar, Wouter H; Haramis, Anna-Pavlina G[et al.] (Elsevier, 2018-01)Notch signaling plays an essential role in the proliferation, differentiation and cell fate determination of various tissues, including the developing pancreas. One regulator of the Notch pathway is GDE2 (or GDPD5), a ... -
Negative regulation of urokinase receptor activity by a GPI-specific phospholipase C in breast cancer cells
van Veen, Michiel; Matas-Rico, Elisa; van de Wetering, Koen; Leyton-Puig, Daniela; Kedziora, Katarzyna M; De Lorenzi, Valentina; Stijf-Bultsma, Yvette; van den Broek, Bram; Jalink, Kees; Sidenius, Nicolai; Perrakis, Anastassis; Moolenaar, Wouter H[et al.] (Elife, 2017-08-29)The urokinase receptor (uPAR) is a glycosylphosphatidylinositol (GPI)-anchored protein that promotes tissue remodeling, tumor cell adhesion, migration and invasion. uPAR mediates degradation of the extracellular matrix ... -
Sequence-dependent trafficking and activity of GDE2, a GPI-specific phospholipase promoting neuronal differentiation.
Salgado-Polo, Fernando; van Veen, Michiel; van den Broek, Bram; Jalink, Kees; Leyton-Puig, Daniela; Perrakis, Anastassis; Moolenaar, Wouter H; Matas-Rico, Elisa[et al.] (The Company of Biologist, 2020-02-10)GDE2 (also known as GDPD5) is a multispanning membrane phosphodiesterase with phospholipase D-like activity that cleaves select glycosylphosphatidylinositol (GPI)-anchored proteins and thereby promotes neuronal differentiation ...