Listar por autor "Minh Thu Nguyen, Marie"
Mostrando ítems 1-6 de 6
-
Amyloid-b seeding and propagation processes in a hAb-KI model of Alzheimer's disease
Trujillo-Estrada, Laura Isabel
; Do Huynh, Kelly; Minh Thu Nguyen, Marie; Cheung, Alwin; Pham Tran, Janine; Núñez-Díaz, Cristina; Forner, Stefania; Martini, Alessandra C.; Da Cunha, Celia; Shahnawaz, Mohammad; Soto, Claudio; Moreno-González, Inés; Gutiérrez-Pérez, Antonia; LaFerla, Frank; Baglietto-Vargas, David[et al.] (2020-12-17)
Recent evidence indicates that Aβ can misfold and aggregate into seeds that structurally corrupt native proteins, mimicking a prion-like process. Several studies using FAD animal models have demonstrated that ... -
Dataset seeding paper JAL.
Andreo-López, Juana; Núñez-Díaz, Cristina; Do Huynh, Kelly; Minh Thu Nguyen, Marie; Da Cunha, Celia; Cantero-Molina, Francisco; Campos-Moreno, Cynthia; Zimbone, Stefania; Bellia, Francesco; Giuffrida, Maria Laura; Trujillo-Estrada, Laura Isabel; García-León, Juan Antonio; Bettinetti-Luque, Miriam; Gámez, Nazaret; Valdés, Catalina; Morales, Rodrigo; Forner, Stefania; Martini, Alessandra C.; Gutiérrez-Pérez, Antonia; LaFerla, Frank; Baglietto-Vargas, David[et al.] (Universidad de Málaga, 2023-11-24)
Este trabajo se centra en el estudio de la propagación de la patología amiloidea en diferentes modelos animales para la Enfermedad de Alzheimer (EA). Los resultados sugieren que existen diversos factores que modulan este ... -
Generation of a humanized Aβ expressing mouse demonstrating aspects of Alzheimer's disease-like pathology.
Baglietto-Vargas, David; Forner, Stefania; Cai, Lena; Martini, Alessandra C; Trujillo-Estrada, Laura; Swarup, Vivek; Minh Thu Nguyen, Marie; Do Huynh, Kelly; Javonillo, Dominic I; Minh Tran, Kristine; Phan, Jimmy; Jiang, Shan; Kramár, Enikö A; Nuñez-Diaz, Cristina; Balderrama-Gutierrez, Gabriela; Garcia, Franklin; Childs, Jessica; Rodriguez-Ortiz, Carlos J; Garcia-Leon, Juan Antonio; Kitazawa, Masashi; Shahnawaz, Mohammad; Matheos, Dina P; Ma, Xinyi; Da Cunha, Celia; Walls, Ken C; Ager, Rahasson R; Soto, Claudio; Gutierrez, Antonia; Moreno-Gonzalez, Ines; Mortazavi, Ali; Tenner, Andrea J; MacGregor, Grant R; Wood, Marcelo; Green, Kim N; LaFerla, Frank M[et al.] (Springer Nature, 2021-04-23)
The majority of Alzheimer’s disease (AD) cases are late-onset and occur sporadically, however most mouse models of the disease harbor pathogenic mutations, rendering them better representations of familial autosomal-dominant ... -
Human and mouse seeds differentially affect AB aggregation by modulating the inflammatory response.
Andreo-López, Juana; Cantero-Molina, Francisco; Bettinetti-Luque, Miriam; Do Huynh, Kelly; Minh Thu Nguyen, Marie; Cheung, Alwin; Pham Tran, Janine; Da Cunha, Celia; Morales-Cabello, Mario; Fatuarte Juli, Ivan; Trujillo-Estrada, Laura Isabel; Núñez-Díaz, Cristina; Cadete-Martini, Alessandra; Forner, Stefania; LaFerla, Frank; Gutiérrez-Pérez, Antonia; Baglietto-Vargas, David[et al.] (2023)
Abstract text: Alzheimer’s Disease (AD) is a neurodegenerative proteinopathy in which Aβ can misfold and aggregate into seeds that structurally corrupt native proteins, mimicking a prionlike process. These amyloid aggregation ... -
Human and mouse seeds differentially affect Aβ aggregation by modulating the inflammatory response
Andreo-López, Juana; Cantero-Molina, Francisco; Bettinetti-Luque, Miriam; Do Huynh, Kelly; Minh Thu Nguyen, Marie; Cheung, Alwin; Pham Tran, Janine; Da Cunha, Celia; Trujillo-Estrada, Laura Isabel; Núñez-Díaz, Cristina; Cadete-Martini, Alessandra; Forner, Stefania; Gutiérrez-Pérez, Antonia; LaFerla, Frank; Baglietto-Vargas, David[et al.] (2023)
Background: Alzheimer’s Disease (AD) is a neurodegenerative proteinopathy in which Aβ can misfold and aggregate into seeds that structurally corrupt native proteins, mimicking a prion-like process. These amyloid aggregation ... -
SPG302 Reverses Synaptic and Cognitive Deficits Without Altering Amyloid or Tau Pathology in a Transgenic Model of Alzheimer's Disease
Trujillo-Estrada, Laura Isabel; Vanderklish, Peter; Minh Thu Nguyen, Marie; Kuang, Run Rong; Nguyen, Caroline; Huynh, Eric; da Cunha, Celia; Ibarra Javonillo, Dominic; Forner, Stefania; Martini, Alessandra C.; Sarraf, Stella; Simmon, Vicent; Baglietto-Vargas, David; LaFerla, Frank[et al.] (Elsevier, 2021-10)
Alzheimer’s disease (AD) is conceptualized as a synaptic failure disorder in which loss of glutamatergic synapses is a major driver of cognitive decline. Thus, novel therapeutic strategies aimed at regenerating synapses ...