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Listar por autor "Granados-Durán, Pablo"
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A model of neuroinflammation and demyelination by intracerebroventricular injection of microbial neuraminidase
Fernández-Llebrez, Pedro; Granados-Durán, Pablo; Gómez-Roldán, María del Carmen; Cifuentes-Rueda, Manuel
; Pérez-Martín, Margarita
; Mateos-Grondona, Jesús
; Rodriguez-de-Fonseca, Fernando; López-Ávalos, María Dolores
[et al.] (2014-07-14)
Neuraminidase from Clostridium perfringens, which cleaves terminal sialic acid from carbohydrate chains, was injected in the lateral ventricle of rats. It diffused in the ipsilateral ventricle, the third ventricle, and ... -
Análisis de la reacción inflamatoria y los procesos degenerativos provocados por la inyección intracerebroventricular de neuraminidasa en rata
Granados-Durán, Pablo (Universidad de Málaga, Servicio de Publicaciones y Divulgación Científica, 2014)Las infecciones víricas y bacterianas del sistema nervioso central (SNC) y la neuroinflamación han sido relacionadas en los últimos años con en el desarrollo de ciertas enfermedades neurodegenerativas, tales como la ... -
FGF2, but not EGF, Induces multiciliated ependymal cells to dedifferentiate and adopt radial glial features in vitro
Mateos-Grondona, Jesús; Granados-Durán, Pablo; Navarro Dueñas, Isabel; Fernández-Llebrez, Pedro
; López-Ávalos, María Dolores
(2014-07-21)
Multiciliated ependymal cells form an epithelium lining most of the ventricular cavities of vertebrates brain. Although considered postmitotic and completely differentiated, ependymal cells maintain some phenotypic ... -
Promotion of structural plasticity in area V2 of visual cortex prevents against object recognition memory deficits in aging and Alzheimer's disease rodents.
Navarro-Lobato, Irene; Masmudi-Martín, Mariam; López-Aranda, Manuel Francisco; López-Téllez, Juan Félix; Delgado, Gloria; Granados-Durán, Pablo; Gaona-Romero, Celia; Carretero-Rey, Marta; Posadas, Sinforiano; Quirós-Ortega, María Elena; Khan, Zafaruddin[et al.] (Wolters Kluwer Medknow, 2023-11-08)
Memory deficit, which is often associated with aging and many psychiatric, neurological, and neurodegenerative diseases, has been a challenging issue for treatment. Up till now, all potential drug candidates have failed ... -
The ependymal detach due to neuraminidase provokes hydrocephalus
Fernández-Arjona, María del Mar; Granados-Durán, Pablo; Gómez-Roldán, María del Carmen; López-Ávalos, María Dolores; Mateos-Grondona, Jesús
; Cifuentes-Rueda, Manuel
; Pérez-Martín, Margarita
; Fernández-Llebrez, Pedro
[et al.] (2015-05-27)
Background: In many cases there seems to exist a tight relationship between the integrity of the ependymal barrier and the onset of hydrocephalus (see 1). We wanted to investigate this by means of a repetitive model that ...