Listar por autor "Ruiz-Sánchez, Antonio Jesús"
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A perspective of nanotechnology in hypersensitivity reactions including drug allergy
Montañez-Vega, María Isabel
; Ruiz-Sánchez, Antonio Jesús; Perez-Inestrosa, Ezequiel (Lippincott Williams & Wilkins, 2010-08)
Purpose of review We provide an overview of the application of the concepts of nanoscience and nanotechnology as a novel scientific approach to the area of nanomedicine related to the domain of the immune system. Particular ... -
Analytical methodologies for the determination of cisplatin
Espinosa-Bosch, Maria; Ruiz-Sánchez, Antonio Jesús; Sánchez-Rojas, María Fuensanta; Bosch-Ojeda, Catalina (ScienceDirect, 2008-07-15)
cis-Diamminedichloroplatinum(II) (cisplatin) is a important chemotherapeutic drug for cancer treatment since 1978. Unfortunately, because of the severe side-effects like nephrotoxicity, ototoxicity, etc., they are administered ... -
Dendrimeric Antigens. New Approaches Towards Detection of IgE‐Mediated Drug Allergy Reactions
Montañez-Vega, María Isabel; Mayorga, Cristobalina; Torres-Jaén, María Josefa; Ruiz-Sánchez, Antonio Jesús; Malkoch, M; Hult, A; Blanca, Miguel; Pérez-de-Inestrosa-Villatoro, Ezequiel[et al.] (RSC Publishing, 2013-05-31)
Drugs are low molecular weight substances which cannot cause an immune response on their own. However, they can act as haptens and form covalent adducts with proteins. The resulting hapten‐carrier (drug‐protein) conjugate ... -
Optical Chemical Biosensors for High Throughput Screening of Drugs
Espinosa Bosh, Maria; Ruiz-Sánchez, Antonio Jesús; Sánchez-Rojas, María Fuensanta; Bosch-Ojeda, Catalina (Bentham Science Publishers Ltd., 2007)
Optical biosensors have been commercially available since the early 1990s, and have been used extensively in many areas of research in the life sciences. Optical biosensors developed for drug analysis generally exploit ... -
Recognition of multiepitope dendrimeric antigens by human immunoglobulin E.
Montañez-Vega, María Isabel; Nájera-Albendín, Francisco; Mayorga, Cristobalina; Ruiz-Sánchez, Antonio Jesús; Vida-Pol, Yolanda; Collado-Martín, Daniel; Blanca, Miguel; Torres-Jaén, María Josefa; Pérez-de-Inestrosa-Villatoro, Ezequiel[et al.] (Elsevier, 2015-02-07)
In vitro drug allergy tests have limited sensitivity, partly due to a poor understanding of the immunological recognition of in vitro drug–protein conjugates. We have designed and synthesized multivalent mono- and bi-epitope ... -
Sensor electroquímico selectivo hacia BPA en aguas residuales mediante polímeros de impresión molecular sobre óxido de grafeno magnético.
Ruiz-Sánchez, Antonio Jesús; Mena Herrera, Lourdes; Montoro-Leal, Pablo; Jiménez Pérez, Rebeca; Martínez Piernas, Ana B.; Sánchez-Trujillo, Irene; López-Guerrero, María del Mar; Vereda-Alonso, Elisa Isabel[et al.] (2024)
El bisfenol A (BPA) es un compuesto orgánico ampliamente utilizado en la producción de plásticos y resinas; el cual se libera fácilmente de estos productos y que puede afectar a la salud humana al ser un disruptor endocrino ... -
Synthesis of all-aliphatic polyamide dendrimers based on a 3,3′-diaminopivalic acid scaffold.
Ruiz-Sánchez, Antonio Jesús; Mesa-Antúnez, Pablo; Barbero, Nekane; Collado-Martín, Daniel; Vida-Pol, Yolanda; Nájera-Albendín, Francisco; Pérez-de-Inestrosa-Villatoro, Ezequiel[et al.] (RSC publication, 2015-03-09)
Over recent years the importance of dendrimers has continued to increase in both life and material sciences. Multiple chemical strategies have been described toward the preparation of dendrimeric structures. Here, we present ... -
The C-Terminus of H-Ras as a Target for the Covalent Binding of Reactive Compounds Modulating Ras-Dependent Pathways
(PLOS One, 2011-01)Ras proteins are crucial players in differentiation and oncogenesis and constitute important drug targets. The localization and activity of Ras proteins are highly dependent on posttranslational modifications at their ...