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Galanin decreases NPYY1R internalization and β- Arrestin2 recruitment
(2015-10-05)We have recently described a Galanin receptor 2(GALR2) and Neuropeptide Y Y1 receptor(NPYY1R) interaction at behavioural, cellular and receptor levels through GALR2/NPYY1R heterodimers. The aim of this work was to study ... -
Galanin interacts with Neuropeptide Y Y1 receptor in the dentate gyrus of the hippocampus through GALR2/NPYY1R heterodimers
(2016-07-11)We have shown Galanin(GAL) and Neuropeptide Y Y1(NPYY1) interactions at behavioural, cellular and receptor levels through GALR2/NPYY1R heterodimers in the amygdala. The aim of this work was to analyze GAL/NPYY1R interactions ... -
Galanin n-terminal fragment (1-15) decreases the voluntary alcohol intake in rats
(2018-06-28)Galanin (GAL) is involved in drug abuse and addiction including alcohol intake. In this work, we have analysed the role of the N-terminal GAL fragment (1-15) [GAL(1-15)] in voluntary ethanol consumption in rats using the ... -
Galanin N-Terminal fragment (1-15) enhances the antidepressant effects of the 5-HT1A receptor agonist 8-OH-DPAT in the Forced Swimming Test.
(2016-07-27)Galanin and Galanin (1-15) [GAL(1-15)] are implicated in anxiety- and depression related behaviors. Moreover, Galanin modulates 5-HT1A receptor (5-HT1AR) function at autorreceptor and postsynaptic level in the brain. In ... -
Galanin N-Terminal fragment (1-15) induces a stronger effect than Galanin in depression- and anxiety- like related behavioural tests in rats.
(2014-07-16)Galanin (GAL) and GAL Receptors are implicated in anxiety- and depression- related behaviours. The GAL N-terminal fragment (1-15) [GAL(1-15)] also induces depressant- and anxiogenic- like actions. In this work, we have ... -
Galanin n-terminal fragment (1-15) induces an anxiety- and depressive-like behaviours in the light/dark and tail suspension tests
(2015-10-21)Galanin N-terminal fragment (1-15) [Gal(1-15)] is involved in mood regulation. We have shown that intracerebroventricular (icv) administration of Gal(1-15) produces a depressive-like behaviour in the forced swim test (FST) ... -
Galanin N-terminal fragment (1-15) reduces alcohol consumption in the self-administration with involvement of mesocorticolimbic system in rats.
(2023)Alcohol Use Disorder (AUD) is a highly prevalent disorder characterized by an impaired ability tostop or control alcohol use despite the adverse consequences. Nowadays, AUD treatment is limiteddue to the low efficacy of ... -
Galanin N-terminal fragment (1− 15) reduces alcohol seeking and alcohol relapse in rats: Involvement of mesocorticolimbic system: dataset
(Universidad de Málaga, 2022)Alcohol Use Disorder (AUD) is among the most prevalent mental illnesses, and due to the low efficacy of the current medication, it is essential to find new biological targets that could modulate alcohol consumption. Since ... -
Galanin N-terminal fragment (1−15) reduces alcohol seeking and alcohol relapse in rats: Involvement of mesocorticolimbic system
(Elsevier, 2022-09)Alcohol Use Disorder (AUD) is among the most prevalent mental illnesses, and due to the low efficacy of the current medication, it is essential to find new biological targets that could modulate alcohol consumption. Since ... -
Galanin n-terminal gragment (1-15) modifies the 5-HT1A receptor against [H3]-8-OH-DPAT binding in the dorsal raphe and hippocampus of the rat
(2016-09-09)We have described that Galanin N-terminal fragment (1-15) [GAL(1-15)] is associated with depressive effects and also modulates the antidepressant effects induced by the 5-HT1A receptor (5-HT1AR) agonist 8-OH-DPAT. The aim ... -
Galanin receptor 2 modifies neuropeptide Y Y1 receptor internalization and β-Arrestin recruitment
(2015-10-05)We have recently described a Galanin receptor 2(GALR2) and Neuropeptide Y Y1 receptor(NPYY1R) interaction at behavioural, cellular and receptor levels through GALR2/NPYY1R heterodimers. The aim of this work was to study ... -
Galanin receptor/neuropeptide y recptor interactions in the central nervous system
(2013-11-20)The presence of Galanin and Neuropeptide Y and/or their receptors in many relevant brain regions related to learning and memory, mood, cardiovascular control and food intake implies that Galanin, and Neuropeptide Y may ... -
Galanin(1-15) enhanced the antidepressant-like effects of escitalopram in the olfactory bulbectomy rats in the forced swimming test through 5-HT1A receptors
(2022-07-12)We previously described that Galanin (1-15) [GAL(1-15)] enhances the antidepressant-like effects induced by the SSRI Fluoxetine in the forced swimming test (FST) in naïve rats. In this work, we have analyzed in olfactory ... -
Galanin(1-15) reverses the impaired long-term memory effect of fluoxetine in the novel object recognition test. Role of 5-HT1A receptor in medial prefrontal cortex
(2019-12-16)In this work, we have studied the effects of GAL(1-15) on FLX- mediated effects on the NOR and the OLM, two tasks where FLX treatment impaired long-term memories 24h post-training. Since the mPFC is a core region for the ... -
Galanin/ Neuropeptide Y Y1 receptor interaction at the cellular and receptor level in the amygdala
(2013-11-18)Galanin (GAL) interacts functionally with Neuropeptide Y Y1 receptor (Y1) in the nucleus tractus solitarius and the arcuate nucleus. Since GAL and Y1 participate in mood disorders, the aim of this work was to analyze GAL/Y1 ... -
Galaxias Activas: alimentando al monstruo
(2015-10-20)Uno de los resultados más relevantes de la astrofísica en los últimos años es que muchas galaxias (incluida nuestra propia Vía Láctea) contienen un gran agujero negro de gran masa en el centro. Cuando uno de estos agujeros ... -
Galectin-3, a novel endogenous TREM2 ligand, detrimentally regulates inflammatory response in Alzheimer's disease.
(Springer, 2019-04-20)Alzheimer's disease (AD) is a progressive neurodegenerative disease in which the formation of extracellular aggregates of amyloid beta (Aβ) peptide, fibrillary tangles of intraneuronal tau and microglial activation are ... -
Galería Central. Un proyecto de innovación colaborativo
(2015-06-09)Este trabajo recoge los programas y resultados alcanzados por Galería Central (GC), un espacio expositivo situado en la Facultad de Ciencias de la Comunicación de la Universidad de Málaga, inaugurado en el curso 2008-2009 ... -
Galería Central. Un proyecto de innovación colaborativo
(2015-06-03)Este trabajo recoge los programas y resultados alcanzados por Galería Central (GC), un espacio expositivo situado en la Facultad de Ciencias de la Comunicación de la Universidad de Málaga, inaugurado en el curso 2008-2009 ... -
Galería de arte virtual
(2016-07-01)Un sistema de gestión de contenidos es una plataforma que permite crear una estructura de soporte para la creación y administración de contenidos. Permite a los administradores y a los usuarios centrarse en el contenido ...