Listar por autor "Medina-Torres, Miguel Ángel"
Mostrando ítems 21-40 de 86
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Copper-containing mesoporous bioactive glass promotes angiogenesis in an in vivo zebrafish model
Romero-Sánchez, Lilian B.; Mari-Beffa, Manuel
; Carrillo Fernández, Paloma; Medina-Torres, Miguel Ángel; Díaz-Cuenca, Aránzazu (2018-10-19)
The osteogenic and angiogenic responses of organisms to the ionic products of degradation of bioactive glasses (BGs) are being intensively investigated. The promotion of angiogenesis by copper (Cu) has been known for more ... -
Creatividad en la ciencia, creatividad de la ciencia
Medina-Torres, Miguel Ángel (Universidad de Málaga, 2006)
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CRISPR for Bio-Art?
Medina-Torres, Miguel Ángel (2018-06-25)
This communication will explain the biotechnological procedure of gene edition based on CRISPR and will discuss the implications that its use could have in the bioartistic praxis. A metaphorical figure has been produced ... -
Danthron, an Anthraquinone Isolated from a Marine Fungus, Is a New Inhibitor of Angiogenesis Exhibiting Interesting Antitumor and Antioxidant Properties
Vidal-Valenzuela, Isabel; Torres-Vargas, José Antonio; Sánchez López, José María; Trigal Martínez, Mónica; García-Caballero, Melissa; Medina-Torres, Miguel Ángel; Rodríguez-Quesada, Ana María[et al.] (MDPI, 2023-05-15)
The role played by a sustained angiogenesis in cancer and other diseases stimulates the interest in the search for new antiangiogenic drugs. In this manuscript, we provide evidence that 1,8- dihydroxy-9,10-anthraquinone ... -
Diseño, aplicación y evaluación de recursos didácticos que faciliten el aprendizaje de la Bioquímica por parte del alumnado universitario de ciencias
(UMA Editorial, 2022)La Bioquímica es un amplio campo de conocimientos que se imparte en todo el mundo, con enfoques adaptados a las diferentes carreras universitarias de ciencias. Los futuros biólogos, químicos, bioquímicos o profesionales ... -
El análogo de las estrigolactonas GR-24 induce cambios en el citoesqueleto de células tumorales y endoteliales y modula su balance rédox
Torres-Vargas, José Antonio; Martínez-Póveda, Beatriz Amparo; Carrillo Fernández, Paloma; Medina-Torres, Miguel Ángel; Rodríguez-Quesada, Ana María (2018-12-12)
Las estrigolactonas son hormonas vegetales con estructura terpenoide, implicadas en el control de una serie de procesos que incluyen la inhibición de la ramificación de la raíz y el brote. Recientemente, se ha descrito el ... -
Estudios de preferencia metabólica en células del “microambiente angiogénico”
Ocaña Farfán, María del Carmen; Martínez-Póveda, Beatriz Amparo; Rodríguez-Quesada, Ana María; Medina-Torres, Miguel Ángel (2016-10-03)
El "redescubrimiento" del efecto Warburg a principios de este siglo XXI y de la elevada glutaminolisis tumoral han contribuido a un renovado interés por el metabolismo en Oncología. Además, estudios recientes han dado ... -
Evaluation of metabolism and biosignaling in the angiogenic microenvironment as potential targets for therapeutic intervention
Medina-Torres, Miguel Ángel; Ocaña Farfán, María del Carmen; Martínez-Póveda, Beatriz Amparo; Carrillo Fernández, Paloma; Urdiales-Ruiz, José Luis; Serrano, José J.; Montañez, Raúl; Rodríguez-Quesada, Ana María[et al.] (2017-08-29)
The "re-discovery" of Warburg effect at the turn of the present millennium has been a key determinant of the current renewed interest on cancer metabolism. In fact, metabolic reprogramming has been identified as one of the ... -
Evaluation of the anti-angiogenic potential of hydroxytyrosol derivatives
Marrero Capitán, Ana Dácil; Martínez-Póveda, Beatriz Amparo; Castilla, Laura; Gallardo, Elena; Espartero Sánchez, José Luis; Carrillo Fernández, Paloma; Rodríguez-Quesada, Ana María; Medina-Torres, Miguel Ángel[et al.] (2018-09-19)
Angiogenesis, a process which allows the formation of new vessels from pre-existing ones, is an essential phenomenon for tumor survival since it allows cancer cells to obtain nutrients and oxygen. This explains the increasing ... -
Exploring the ring-closing metathesis for the construction of the solomonamide macrocyclic core: identification of bioactive precursors
Cheng-Sánchez, Iván; Sánchez-Ruiz, Antonio; Martínez-Póveda, Beatriz Amparo; Medina-Torres, Miguel Ángel; Carrillo Fernández, Paloma; Rodríguez-Quesada, Ana María; López-Romero, Juan Manuel; Sarabia-García, Francisco Ramón[et al.] (2018-10-19)
New synthetic strategies directed toward the novel cyclopeptides solomonamides have been explored utilizing an olefin metathesis as the key reaction. In the various strategies investigated, we worked on minimally oxidized ... -
Fasentin, a glucose uptake inhibitor, is also able to inhibit angiogenesis
Ocaña Farfán, María del Carmen; Carrillo Fernández, Paloma; Martínez-Póveda, Beatriz Amparo; Rodríguez-Quesada, Ana María; Medina-Torres, Miguel Ángel (2017-10-31)
The role of glucose on endothelial cell (EC) metabolism and angiogenesis has been an emerging issue in the last few years. Some inhibitors of glucose metabolism, such as 2-deoxyglucose, have been shown to have anti-angiogenic ... -
Fishing anti(lymph)angiogenic drugs with zebrafish
García-Caballero, Melissa; Rodríguez-Quesada, Ana María; Medina-Torres, Miguel Ángel; Mari-Beffa, Manuel (2018-10-19)
Zebrafish, an amenable small teleost fish with a complex mammal-like circulatory system, is being increasingly used for drug screening and toxicity studies. It combines the biological complexity of in vivo models with a ... -
Gastronomía Bioactiva: compuestos bioactivos en alimentos y quimioprevención en enfermedades de alta prevalencia
Martínez-Póveda, Beatriz Amparo; Marrero Capitán, Ana Dácil; Rodríguez-Quesada, Ana María; Medina-Torres, Miguel Ángel (43 Congreso Anual SEBBM, 2021)
La quimioprevención de enfermedades basada en la dieta ha surgido en los últimos años como un enfoque interesante para la prevención, e incluso la ralentización de fases iniciales, en patologías de alta prevalencia como ... -
The graphene oxide species induce a different biological response in SN4741 Parkinson cell line
Rodríguez-Losada, Noela; Wendelbo, Rune; Aguirre-Gómez, José Ángel; Ocaña Farfán, María del Carmen; Arráez-Sánchez, Miguel Ángel; Díaz-Casares, Amelia; Medina-Torres, Miguel Ángel; Martínez-Moreno, José Manuel; Arenas, Ernest; Narváez-Bueno, José Ángel[et al.] (2019-09-30)
Introduction: Graphene Oxide (GO)has recently emerged as a reliable material to create scaffolds for the neural tissue because of its biocompatibility, electroconductive and physicochemical properties. Graphene is a ... -
Homocysteine treatment alters redox capacity of both endothelial and tumor cells
Díaz-Santiago, Elena Dolores; Rodríguez Caso, Luis; Cárdenas García, Casimiro; Serrano, José J.; Rodríguez-Quesada, Ana María; Medina-Torres, Miguel Ángel[et al.] (2015-10-22)
Homocysteine is a non-proteinogenic amino acid playing key roles in two interconnected metabolic pathways, namely, the activated methyl cycle and the linear trans-sulfuration pathway that allows the conversion of methionine ... -
Hydroxytyrosol targets extracellular matrix remodeling by endothelial cells and inhibits both ex vivo and in vivo angiogenesis
García-Vilas, Javier A.; Rodríguez-Quesada, Ana María; Medina-Torres, Miguel Ángel (Elsevier, 2017-04)
The health benefits of olive oil are attributed to their bioactive compounds, such as hydroxytyrosol. Previously, we demonstrated that hydroxytyrosol inhibits angiogenesis in vitro. The present study aimed to: i) get further ... -
Identification and characterization of new anti-angiogenic compounds from natural sources
Carrillo Fernández, Paloma; Ocaña Farfán, María del Carmen; Martínez-Póveda, Beatriz Amparo; Medina-Torres, Miguel Ángel; Rodríguez-Quesada, Ana María (2017-07-21)
The inhibition of angiogenesis has attracted broad attention in the field of pharmacological research, not only for cancer, but for other angiogenesis dependent diseases including ophthalmic, cutaneous and inflammatory ... -
Imagen y ciencia
Medina-Torres, Miguel Ángel (Universidad de Málaga, 2014)
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Inhibition of Endothelial Inflammatory Response by HT-C6, a Hydroxytyrosol Alkyl Ether Derivative.
Marrero Capitán, Ana Dácil; Castilla, Laura; Bernal, Manuel; Manrique-Poyato, María Inmaculada; Posligua-García, Joel; Moya-Utrera, Federico; Porras Alcalá, Cristina; Espartero Sánchez, José Luis; Sarabia-García, Francisco Ramón; Rodríguez-Quesada, Ana María; Medina-Torres, Miguel Ángel; Martínez-Póveda, Beatriz Amparo[et al.] (MDPI, 2023-07-28)
Hydroxytyrosol (HT) is a bioactive phenolic compound naturally present in olives and extra virgin olive oil (EVOO) which is described as an antioxidant, antitumoral and antiangiogenic molecule. Previous studies of ... -
Integrating differential expression, co-expression and gene network analysis for the identification of common genes associated with tumor angiogenesis deregulation
Monterde, Beatriz; Rojano Rivera, María Elena; Córdoba Caballero, José; Seoane Zonjic, Pedro; Perkins, James Richard; Medina-Torres, Miguel Ángel; García-Ranea, Juan Antonio[et al.] (Elsevier, 2023)
Angiogenesis is essential for tumor growth and cancer metastasis. Identifying the molecular pathways involved in this process is the first step in the rational design of new therapeutic strategies to improve cancer treatment. ...