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Listar por autor "Nájera-Albendín, Francisco"
Mostrando ítems 21-29 de 29
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Slightly congested amino terminal dendrimers. The synthesis of amide-based stable structures on a large scale.
Morgado Benítez, Anjara; Nájera-Albendín, Francisco; Lagunas, Anna; Samitier, Josep; Vida-Pol, Yolanda; Pérez-de-Inestrosa-Villatoro, Ezequiel[et al.] (Royal Society of Chemistry, 2021-08-17)Nowadays, amino terminal dendrimers are appealing materials for biological applications due to their multivalence and the versatile conjugation of the amino groups. However, the high reactivity of these terminal groups can ... -
Spontaneous [2+2] macrocyclization trhough dynamic covalent aminal bonds
Ruiz-Sanchez, Antonio Jesus; Carbajo, Daniel; Nájera-Albendín, Francisco; Alfonso, Ignacio; Pérez-de-Inestrosa-Villatoro, Ezequiel (2022-06)Aminals are characterized by the connectivity of two amino groups to the same carbon atom, being the nitrogenated equivalent of acetals. Unlike acetals, aminals have been slightly underexplored in dynamic covalent chemistry ... -
Syntehsis and use of dendrimeric structures as a tool in biomedicine
Pérez-de-Inestrosa-Villatoro, Ezequiel; Vida-Pol, Yolanda; Molina, Noemi; Morgado, Anjara; Nájera-Albendín, Francisco (2019-10-28)Specific cell interactions of surfaces grafted dendrimers have been applied to the study of cell adhesion. We have studied also the application of dendrimer-based uneven nanopatterns to evaluate the local RGD surface density ... -
Synthesis and Biomedical aplications of BAPAD: Bisaminoalkylpolyamide Dendrimers
Pérez-de-Inestrosa-Villatoro, Ezequiel; Ruiz-Sanchez, Antonio Jesus; Vida-Pol, Yolanda; Collado-Martín, Daniel; Nájera-Albendín, Francisco; Mesa, Pablo; Morato, Isabel; Barbero, Nekane[et al.] (2014-02-06)A new class of Dendrimeric Systems (Dendrimers and Dendrons) and the study of their properties in molecular recognition processes are presented. These Dendrimers (BAPAD: BisAminoalkylPolyAmideDendrimers), are designed to ... -
Synthesis and characterization of new chromophores with two-photon absorption properties and study of their application in bioimaging
Benítez-Martín, Carlos (UMA Editorial, 2022-02-02)A consencuencia de la naturaleza no invasiva de la luz, los métodos basados en fluorescencia han adquirido un rol fundamental para la compresión de los procesos biológicos, comprendiendo desde el estudio de procesos celulares ... -
Synthesis of fluorescent BAPAD dendrimeric structrures for biomedical applications
Mesa-Antunez, Pablo; Collado-Martín, Daniel; Nájera-Albendín, Francisco; Pérez-de-Inestrosa-Villatoro, Ezequiel (2014-02-03)In this work, we present the synthesis and characterization of BAPAD1 fluorescent Dendrimeric-Antigens (DeAn), to study the dendritic cell maturation as a test to detect drug allergy reactions. Recently our research group ... -
Synthesis of fluorescent dendrimeric antigen efficiently internalized by human dendritic cells
Mesa-Antunez, Pablo; Collado-Martín, Daniel; Vida-Pol, Yolanda; Nájera-Albendín, Francisco; Fernández-Duarte, Tahía Diana; Torres-Jaén, María Josefa; Pérez-de-Inestrosa-Villatoro, Ezequiel[et al.] (Servicio de Publicaciones de la Universidad de Huelva, 2016)A new fluorescent dendrimeric antigen (DeAn) based on a dendron with amoxicilloyl terminal groups has been synthetized. The synthesis implies a novel class of all-aliphatic polyamide dendrimer (BisAminoalkylPolyAmide ... -
Tailoring two-photon fluorescent probes for pH bioimaging in living cells
Nájera-Albendín, Francisco; Benítez-Martín, Carlos; Guadix-Domínguez, Juan Antonio; Pearson, John R.; Pérez-Pomares, José María; Pérez-de-Inestrosa-Villatoro, Ezequiel[et al.] (2022-06-27)Fluorescence biosensors are indispensable basic tools in modern biology. These type of molecules allow real-time visualization of biological events inside living cells. Especially important in many of these processes ... -
Tuning pKa in new molecules based on indolines for two-photon absorption bioimaging applications
Benítez-Martín, Carlos; Nájera-Albendín, Francisco; Pérez-de-Inestrosa-Villatoro, Ezequiel (Real Sociedad Española de Química, 2018-06-20)Fluorescence-based biosensors have become essential tools for modern biology, allowing real-time monitoring of biological processes within living cells. The differences between pH play a significant role in multiple ...