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Listar por autor "Borrego-García, Juan José"
Mostrando ítems 21-40 de 42
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Human gut microbiome, diet, and mental disorders.
Borrego Ruíz, Alejandro; Borrego-García, Juan José (Springer, 2024-04-01)Diet is one of the most important external factor shaping the composition and metabolic activities of the gut microbiome. The gut microbiome plays a crucial role in host health, including immune system development, nutrients ... -
Immune gene expression in gilthead seabream after nervous necrosis virus (NNV) challenge
Gémez-Mata, Juan; Leiva-Rebollo, Rocío; Moreno-García, Patricia; Bandín Matos, Isabel; Borrego-García, Juan José; Labella Vera, Alejandro Manuel; Castro-López, María Dolores[et al.] (2022-09)Viral nervous necrosis (VNN) is a disease that affects farmed fish worldwide. Its etiologic agent is the nervous necrosis virus (NNV), genus Betanodavirus, family Nodaviridae. NNV are small and non-enveloped viruses with ... -
Immune response of DNA vaccinated-gilthead seabream against LCDV-Sa infection: relevance of the inflammatory process.
Leiva-Rebollo, Rocío; Gémez-Mata, Juan; Castro-López, María Dolores; Borrego-García, Juan José; Labella Vera, Alejandro Manuel (2023)Lymphocystis disease is one of the main viral pathologies affecting cultured gilthead seabream in the Mediterranean area. Recently, we have developed a DNA-vaccine based on the major capsid protein of the Lymphocystis ... -
Immune response of gilthead seabream (Sparus aurata) after experimental infection with lymphocystis disease virus (LCDV-Sa)
Leiva-Rebollo, Rocío; Labella Vera, Alejandro Manuel; Castro-López, María Dolores; Borrego-García, Juan José (2019-07-29)Lymphocystis disease (LCD) is caused by the lymphocystis disease virus (LCDV) (family Iridoviridae), affecting more than 150 fish species from both marine and freshwater environments. A few studies have been focused on the ... -
Immune response of gilthead seabream infected with wild and mutant nervous necrosis virus reassortants.
Gémez-Mata, Juan; Leiva-Rebollo, Rocío; Moreno-García, Patricia; Borrego-García, Juan José; Labella Vera, Alejandro Manuel; Castro-López, María Dolores[et al.] (2023)Viral nervous necrosis (VNN) is a disease that affects farmed fish worldwide. Its etiologic agent is the nervous necrosis virus currently classified into 4 species: SJNNV, RGNNV, TPNNV and BFNNV. In Southern Europe, ... -
Immune response of vaccinated juvenile gilthead seabream (Sparus aurata) after LCDV-Sa infection
Leiva-Rebollo, Rocío; Gémez-Mata, Juan; Borrego-García, Juan José; Castro-López, María Dolores; Labella Vera, Alejandro Manuel (2022-09)Lymphocystis disease is one of the main viral pathologies affecting cultured gilthead seabream in the Mediterranean area. In our group, a DNA-vaccine has been developed based on the major capsid protein (MCP) of the ... -
Immunogene expression analysis in betanodavirus infected-Senegalese sole using an OpenArray® platform.
Gémez-Mata, Juan; Labella Vera, Alejandro Manuel; Bandín Matos, Isabel; Borrego-García, Juan José; García-Rosado, Esther (ELSEVIER, 2021-03-30)The transcriptomic response of Senegalese sole (Solea senegalensis) triggered by two betanodaviruses with different virulence to that fish species has been assessed using an OpenArray® platform based on TaqMan™ quantitative ... -
In vitro viral coexistence decreases Striped Jack Nervous Necrosis Virus (SJNNV) but favours Red-spotted Grouper Nervous Necrosis Virus (RGNNV) replication
López-Jimena, Benjamín; Alonso-Sánchez, María del Carmen; Infante, Carlos; Castro-López, María Dolores; Borrego-García, Juan José; García-Rosado, Esther[et al.] (European Association of Fish Pathologists, 2013)In this study, several assays have been performed to characterise the effect of the RGNNV-SJNNV coexistence (coinfection and superinfection) on the replication of each genotype on E-11 cells.The results obtained showed the ... -
Incidencia de los virus de la enfermedad de linfocistis (LCDV-Sa), papillomavirus (SaPV1) y poliomavirus (SaPyV1) en doradas cultivadas en el área mediterránea
Labella Vera, Alejandro Manuel; Leiva, Rocío; Alejo, Alí; Borrego-García, Juan José; Castro-López, María Dolores (2018-10-22)La enfermedad de linfocistis (LCD), causada por el virus de la enfermedad de linfocistis (LCDV), es una patología común descrita en más de 150 especies de peces en todo el mundo, siendo la enfermedad de etiología viral más ... -
Infection of Artemia sp. by Lymphocystis disease virus (LCDV)
Jiménez Valverde, Estefanía; Cano, Irene; García-Rosado, Esther; Alonso-Sánchez, María del Carmen; Borrego-García, Juan José; Castro-López, María Dolores[et al.] (2013-12-10)In the present work, different developmental stages of Artemia sp. (metanauplius, juvenile and adult) were experimentally infected with LCDV by immersion. Results of viral quantification (both by qPCR and cell-culture viral ... -
Novel polyomavirus and papillomavirus detected in gilthead seabream infected by lymphocystis disease virus
Labella Vera, Alejandro Manuel; Carrera, David; López-Bueno, Alberto; Alejo, Alí; Borrego-García, Juan José; Castro-López, María Dolores[et al.] (Institute for Veterinary Medical Research, Budapest, Hungary, 2017)Lymphocystis disease virus (LCDV), a member of the genus Lymphocystivirus, family Iridoviridae, is the etiological agent of the lymphocystis disease (LCD), a common pathology that has been described in more than 150 ... -
Papel del inmunogen isg15 de lubina (Dicentrarchus labrax) en las infecciones por betanodavirus
Moreno, Patricia; García-Rosado, Esther; Borrego-García, Juan José; Alonso-Sánchez, María del Carmen (Universidad de Oviedo, 2016)En peces, al igual que en vertebrados superiores, la respuesta antiviral innata está mediada por el sistema interferón tipo I (IFN I), que actúa mediante la activación de genes denominados isg (interferon-stimulated genes), ... -
Pathogenesis and transmission of lymphocystis disease virus (LCDV) in gilthead seabream (Sparus aurata L.)
Jiménez Valverde, Estefanía (UMA Editorial, 2016)La enfermedad de linfocistis (LCD) se ha descrito en más de 140 especies diferentes de peces teleósteos, tanto marinos como dulceacuícolas, y tiene una amplia distribución geográfica. Su agente etiológico es el virus de ... -
Persistencia del virus de la enfermedad de linfocistis (LCDV) en agua
Leiva, Rocío; Borrego-García, Juan José; Castro-López, María Dolores; Labella Vera, Alejandro Manuel (Universidad de Oviedo, 2016)El virus de la enfermedad de linfocistis (LCDV), perteneciente al género Lymphocystivirus (familia Iridoviridae), es el agente etiológico de la enfermedad de linfocistis (LCD), principal patología de origen vírico descrita ... -
Resultados de la estrategia vacunal universal VHB (Virus Hepatitis B). Hospital Materno Infantil. Málaga. 1995-2014
Calbo-Ortín, María del Carmen (UMA Editorial, 2017-10-11)Introducción/motivación: En Andalucía se establece desde 01-enero-1995 , la "Estrategia Vacunal Universal frente a Hepatitis B para los Recién Nacidos (RN)" , iniciada en el propio Hospital y antes de su Alta tras el ... -
RRGNNV capsid protein amino acids 247 and 270 are involved in betanodavirus virulence to European sea bass (Dicentrarchus labrax)
Moreno, Patricia; Souto, Sandra; Leiva-Rebollo, Rocío; García-Rosado, Esther; Borrego-García, Juan José; Bandín Matos, Isabel; Alonso-Sánchez, María del Carmen[et al.] (2019-09-18)Recombinant RGNNV viruses harbouring SJNNV-type amino acids at positions 247 and/or 270 (Mut247Dl965, Mut270Dl965, Mut247+270Dl965) were generated by reverse genetics. The effect of these modifications on viral replication ... -
Senegalese sole immune response against betanodavirus recombinants harboring modifications in the 3' terminal region of the RNA1
Gémez-Mata, Juan; Labella Vera, Alejandro Manuel; Souto, Sandra; Bandín Matos, Isabel; Borrego-García, Juan José; García-Rosado, Esther[et al.] (2021-09)The nervous necrosis virus (NNV) is the etiological agent of the viral nervous necrosis (VNN), a disease affecting a high number of fish species worldwide. NNV genome is composed of two segments RNA1 and RNA2, encoding the ... -
Senegalese sole transcriptomic profiles in response to different betanodavirus RGNNV/SJNNV reassortant strains
Labella Vera, Alejandro Manuel; Borrego-García, Juan José; Manchado, Manuel; Bandín Matos, Isabel; Castro-López, María Dolores; Alonso-Sánchez, María del Carmen; García-Rosado, Esther[et al.] (2017)Betanodaviruses are the causative agents of viral nervous necrosis (VNN), a disease that has been reported in more than 40 marine and freshwater fish species worldwide, including Senegalese sole (Solea senegalensis). Based ... -
Surveillance studies of Lymphocystis disease virus in farmed gilthead seabream (Sparus aurata) by real-time PCR
Jiménez Valverde, Estefanía; Labella Vera, Alejandro Manuel; Leiva, Rocío; Borrego-García, Juan José; Castro-López, María Dolores (2015-09-16)Lymphocystis disease (LCD) is the main viral infection reported to affect cultured gilthead seabream (Sparus aurata) in Southern Atlantic and Mediterranean aquaculture. Its etiological agent is the Lymphocystis disease ... -
Susceptibility of juvenile european sea bass (dicentrarchus labrax) to different viral nervousnecrosis virus (VNNV) isolates
López-Jimena, Benjamín; García-Rosado, Esther; Souto-Pereira, Sandra; Infante, Carlos; Borrego-García, Juan José; Alonso-Sánchez, María del Carmen[et al.] (EAFP, 2013-09-02)In this study, the susceptibility of 5-g juvenile European sea bass was evaluated by intramuscular injection (105 TCID50/g) using isolates belonging to the RGNNV and SJNNV genotypes as well as a reassortant isolate ...