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Listar por autor "Martínez-Poveda, Beatriz"
Mostrando ítems 21-39 de 39
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Learning contract, co-operative and flipped learning as useful tools for studying metabolism
Martínez-Póveda, Beatriz Amparo; García Ponce, Ángel Luis; Blanco-López, Ángel; Rodríguez-Quesada, Ana María; Suárez-Marín, María Fernanda; Alonso-Carrión, Francisco José; Medina-Torres, Miguel Ángel[et al.] (2018-06-25)Undergraduate students in Biology identify Metabolic Biochemistry as a particularly difficult subject. This is due to the fact that students need to interconnect properly all the contents of its syllabus throughout their ... -
Libro de actas del Workshop Internacional Metabolic Reprogramming as a Target for Cancer and Other Diseases
Martínez-Póveda, Beatriz Amparo; Guadix-Domínguez, Juan Antonio; Medina-Torres, Miguel Ángel (2018-12-17)Este libro sobre el Workshop Internacional Metabolic Reprogramming as a Target for Cancer and Other Diseases se ha publicado con el apoyo económico de los fondos para difusión y divulgación del Proyecto del Plan Estatal ... -
Marine sponge as a source of antiangiogenic compounds. The case of aeroplysinin-1
Rodríguez-Quesada, Ana María; Martínez-Póveda, Beatriz Amparo; Rodríguez-Nieto, S; Medina-Torres, Miguel Ángel (2014-04-02)The vast majority of the natural compounds that have been previously described as inhibitors of angiogenesis have been isolated from plants and terrestrial microorganisms, mainly due to their higher availability and because ... -
Medida de glucosa en refrescos: una útil herramienta para ilustrar el aprendizaje de los fundamentos del análisis enzimático
Martínez-Póveda, Beatriz Amparo; García-Ponce, Ángel Luis; Blanco-López, Ángel; Medina-Torres, Miguel Ángel; Rodríguez-Quesada, Ana María (2016-11-02)Es indudable la relevancia que el análisis enzimático tiene en el ámbito de la Bioquímica, la Química Clínica y la Química de la Alimentación, entre otras. En la asignatura “Bioquímica Aplicada” de cuarto curso ... -
Metabolic preference studies in cells of the tumor microenvironment
Ocaña Farfán, María del Carmen; Martínez-Póveda, Beatriz Amparo; Rodríguez-Quesada, Ana María; Medina-Torres, Miguel Ángel (2016-10-03)In the last years, the rediscovery of the Warburg effect and high tumoral glutaminolysis has lead to a renewed interest in cancer metabolism. Moreover, recent studies have put some importance in endothelial cells metabolism. ... -
Metabolism within the tumor microenvironment and its implication on cancer progression: an ongoing therapeutic target
Martínez-Póveda, Beatriz Amparo; Medina-Torres, Miguel Ángel; Ocaña Farfán, María del Carmen; Rodríguez-Quesada, Ana María (2018-10-19)Since reprogramming energy metabolism is considered a new hallmark of cancer, tumor metabolism is again in the spotlight of cancer research. Many studies have been carried out and many possible therapies have been developed ... -
Non-targeted metabolomics characterization of Annona muricata leaf extracts with anti-angiogenic activity
Cárdenas García, Casimiro; Torres-Vargas, José Antonio; Cárdenas Valdivia, Abel; Jurado, Nuria; Rodríguez-Quesada, Ana María; García-Caballero, Melissa; Martínez-Póveda, Beatriz Amparo; Medina-Torres, Miguel Ángel[et al.] (ELSEVIER, 2021-11)The tropical plant Annona muricata has been widely used for traditional ethnobotanic and pharmacologic applications. Extracts from different parts of this plant have been shown to have a wide range of biological activities. ... -
(-)-Oleacein and (-)-oleocanthal, two phenolic compounds present in Extra Virgin Olive Oil, inhibit angiogenesis
Ortega Vidal, Juan; Salido, Sofía; Altarejos, Joaquín; Marrero Capitán, Ana Dácil; Rodríguez-Quesada, Ana María; Martínez-Póveda, Beatriz Amparo; Medina-Torres, Miguel Ángel[et al.] (2022-11)Phenolic compounds in the Mediterranean diet contribute to many of the health-related benefits accounted in this dietary choice. (-)-Oleocanthal and the less studied (-)-oleacein, are two phenolic compounds present in the ... -
A practice project to prevent the cookbook model as modus operandi for biochemistry laboratory learning
García-Ponce, Ángel Luis; Martínez-Póveda, Beatriz Amparo; Blanco-López, Ángel; Medina-Torres, Miguel Ángel; Rodríguez-Quesada, Ana María (2018-07-02)Laboratory learning is a crucial component of chemistry and biochemistry instruction and should be conceived as a way to develop students’ reasoning, technical or practical skills, introducing them into the scientific ... -
A problem-/case-based learning approach as an useful tool for studying glycogen metabolism and its regulation
García-Ponce, Ángel Luis; Martínez-Póveda, Beatriz Amparo; Blanco-López, Ángel; Rodríguez-Quesada, Ana María; Suárez-Marín, María Fernanda; Alonso-Carrión, Francisco José; Medina-Torres, Miguel Ángel[et al.] (2020-09-23)Metabolism and its regulation is one of the most complex and difficult topics for students learning biochemistry. A problem-/case-based learning (PBL) approach can be useful to help biochemistry students to fulfill the ... -
Role of glucose, glutamine and palmitate in endothelial and tumor metabolism
Ocaña Farfán, María del Carmen; Martínez-Póveda, Beatriz Amparo; Rodríguez-Quesada, Ana María; Medina-Torres, Miguel Ángel (2016-12-22)Glucose and glutamine are the major sources of energy for mammalian cells. In tumors, Warburg effect and glutaminolysis have been largely studied. On the other hand, a major role of glucose in angiogenesis has been ... -
Study of the antitumor potential of stauprimide in breast cancer
Carrillo Fernández, Paloma; Téllez Quijorna, Clara; Bernal, Manuel; Rodríguez-Quesada, Ana María; Medina-Torres, Miguel Ángel; Martínez-Póveda, Beatriz Amparo[et al.] (2021)Stauprimide, a semi-synthetic derivative of staurosporine, was characterized in 2009 as a potent differentiation-enhancing compound in embryonic stem cells [1]. Although it was first thought that this compound could maintain ... -
Synthesis and biological activity of a new class of antitumor cyclopeptides based on the solomonamides
Cheng-Sánchez, Iván; Carrillo Fernández, Paloma; Martínez-Póveda, Beatriz Amparo; Rodríguez-Quesada, Ana María; Medina-Torres, Miguel Ángel; Sarabia-García, Francisco Ramón[et al.] (2018-10-15)Solomonamides A (1) and B (2) are novel natural products recently isolated from the marine sponge Theonella swinhoei [1]. Preliminary structural studies revealed an unprecedented cyclic peptide type structure. Interestingly, ... -
Synthesis and Biological Evaluation of Depudecin Analogues
Cheng-Sánchez, Iván; Carrillo Fernández, Paloma; García-Ruiz, Cristina; Martínez-Póveda, Beatriz Amparo; Rodríguez-Quesada, Ana María; Medina-Torres, Miguel Ángel; Sarabia-García, Francisco Ramón[et al.] (2019-09-18)(-)-Depudecin (1) (Figure 1), isolated from the culture broths of the fungus Alternaria brassicicola,1 and later, from the weed pathogen Nimbya scirpicola,2 has been identified as a selective inhibitor of histone deacetylases ... -
The enzymatic determination of glucose in carbonated beverages: a useful tool for the undergraduate students to learn the basis of enzymatic analysis and the comparison of two analytical methods
García-Ponce, Ángel Luis; Martínez-Póveda, Beatriz Amparo; Blanco-López, Ángel; Medina-Torres, Miguel Ángel; Rodríguez-Quesada, Ana María (2017-03-20)The importance of enzymatic analysis in biochemistry, clinical chemistry and food chemistry is undoubted. The course "Applied Biochemistry" in our Faculty is aimed to undergraduate students of Chemistry and Biochemistry. ... -
The Extra Virgin Olive Oil phenolic compounds () oleacein and () oleocanthal inhibit tumor cell autophagy
Marrero Capitán, Ana Dácil; Posligua-García, Joel; Bernal, Manuel; Ortega Vidal, Juan; Salido, Sofía; Altarejos, Joaquín; Rodríguez-Quesada, Ana María; Martínez-Póveda, Beatriz Amparo; Medina-Torres, Miguel Ángel[et al.] (2023)Our group has recently shown that the antitumor Extra Virgin Olive Oil phenolic compounds (—)oleocanthal and (—)oleacein also behave as antiangiogenic agents. Interestingly, it has been described that phenolic compounds ... -
The immunomodulator dimethyl taconite inhibits several key steps of angiogenesis in cultured endothelial cells
Vidal-Valenzuela, Isabel; Fernández-Florido, Elena; Marrero Capitán, Ana Dácil; Castilla, Laura; Rodríguez-Quesada, Ana María; Martínez-Póveda, Beatriz Amparo; Medina-Torres, Miguel Ángel[et al.] (2022)Dimethyl itaconate (DMI) is a cell-permeable derivative of itaconate, a known immunomodulator metabolite synthesized from the Krebs cycle intermediate cis-aconitate by the enzyme aconitate dehydrogenase. Although DMI is ... -
The noni anthraquinone damnacanthal is a multi-kinase inhibitor with potent anti-angiogenic effects
García-Vilas, Javier A.; Pino-Ángeles, Almudena; Martínez-Póveda, Beatriz Amparo; Rodríguez-Quesada, Ana María; Medina-Torres, Miguel Ángel (Elsevier, 2017-01)The natural bioactive compound damnacanthal inhibits several tyrosine kinases. Herein, we show that -in fact- damancanthal is a multi kinase inhibitor. A docking and molecular dynamics simulation approach allows getting ... -
The synthetic molecule stauprimide impairs cell growth and migration in triple-negative breast cancer
Carrillo Fernández, Paloma; Bernal Muñoz, Manuel; Téllez Quijorna, Clara; Marrero Capitán, Ana Dácil; Vidal-Valenzuela, Isabel; Castilla, Laura; Caro Salazar, Carlos; Domínguez Moreno, Alejandro; García-Martín, María Luisa; Rodríguez-Quesada, Ana María; Medina-Torres, Miguel Ángel; Martínez-Póveda, Beatriz Amparo[et al.] (Elsevier, 2022-12-14)Stauprimide, a semi-synthetic derivative of staurosporine, is known mainly for its potent differentiation-enhancing properties in embryonic stem cells. Here, we studied the effects of stauprimide in cell growth and migration ...