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Listar por autor "Alonso-Sánchez, María del Carmen"
Mostrando ítems 21-40 de 48
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Extractos del probiótico Shewanella putrefaciens Pdp11 protegen frente a la infección por RGNNV en cultivo celular
Moreno, Patricia; Balebona-Accino, María del Carmen; Moriñigo-Gutiérrez, Miguel Ángel; Alonso-Sánchez, María del Carmen; Béjar-Alvarado, Julia; García-Rosado, Esther[et al.] (2022)El agente etiológico de la retinopatía y encefalitis viral (VER) es el virus de la necrosis nerviosa (VNN). Aunque esta enfermedad puede causar una elevada mortalidad en numerosas especies de peces, no existen métodos ... -
First isolation of Photobacterium damselae ssp. damselae from cultured redbanded seabream, Pagrus auriga Valenciennes, in Spain
Labella Vera, Alejandro Manuel; Alonso-Sánchez, María del Carmen; Infante, Carlos; Cardenas, Salvador; López-Romalde, Sonia; Machado, Manuel; Borrego-García, Juan José[et al.] (Blackwell Publishing Ltd, 2006-03-14)This is the first report of the isolation of P. damselae ssp. damselae from redbanded seabream, a sparid fish newly cultured in southern Spain. A low variability in the biochemical profile among the P. damselae ssp. ... -
Genomic characterization and transcription analysis of European sea bass (Dicentrarchus labrax) rtp3 genes
Moreno-García, Patricia; Gémez-Mata, Juan; Álvarez-Torres, Daniel; García-Rosado, Esther; Béjar-Alvarado, Julia; Alonso-Sánchez, María del Carmen[et al.] (Elsevier, 2023-10-23)Fish RTP3, belonging to the receptor-transporting protein family, display several functions, including a putative antiviral role as virus-responsive gene. In this work, we have identified and characterized two different ... -
Genomic characterization and transcription analysis of European sea bass (Dicentrarchus labrax) rtp3 genes.
Moreno, Patricia; Gémez-Mata, Juan; Álvarez-Torres, Daniel; García-Rosado, Esther; Béjar-Alvarado, Julia; Alonso-Sánchez, María del Carmen[et al.] (Elsevier, 2023-10-23)Fish RTP3, belonging to the receptor-transporting protein family, display several functions, including a putative antiviral role as virus-responsive gene. In this work, we have identified and characterized two different ... -
Gilthead seabream (Sparus aurata) Mx proteins show positive and negative synergy in their antiviral activity
Fernández-Trujillo, M. Alejandra; García-Rosado, Esther; Alonso-Sánchez, María del Carmen; Borrego-García, Juan José; Álvarez-Herrero, María del Carmen; Béjar-Alvarado, Julia[et al.] (2014-10-07)Due to their direct antiviral activity, Mx proteins play a main role in the response mediated by the type I interferon against viral infections. The study of the farmed fish gilthead seabream Mx genes is specially interesting, ... -
Immune Response of Senegalese Sole against Betanodavirus Mutants with Modified Virulence.
Gémez Mata, Juan; Souto, Sandra; Bandin, Isabel; Alonso-Sánchez, María del Carmen; Borrego-García, Juan José; Labella Vera, Alejandro Manuel; García-Rosado, Esther[et al.] (MDPI, 2021-10-27)Nervous necrosis virus (NNV), genus Betanodavirus, the etiological agent of the viral encephalopathy and retinopathy (VER), presents a genome with two positive-sense single-stranded RNA segments. Striped jack nervous ... -
In vitro viral coexistence decreases Striped Jack Nervous Necrosis Virus (SJNNV) but favours Red-spotted Grouper Nervous Necrosis Virus (RGNNV) replication
López-Jimena, Benjamín; Alonso-Sánchez, María del Carmen; Infante, Carlos; Castro-López, María Dolores; Borrego-García, Juan José; García-Rosado, Esther[et al.] (European Association of Fish Pathologists, 2013)In this study, several assays have been performed to characterise the effect of the RGNNV-SJNNV coexistence (coinfection and superinfection) on the replication of each genotype on E-11 cells.The results obtained showed the ... -
Infection of Artemia sp. by Lymphocystis disease virus (LCDV)
Jiménez Valverde, Estefanía; Cano, Irene; García-Rosado, Esther; Alonso-Sánchez, María del Carmen; Borrego-García, Juan José; Castro-López, María Dolores[et al.] (2013-12-10)In the present work, different developmental stages of Artemia sp. (metanauplius, juvenile and adult) were experimentally infected with LCDV by immersion. Results of viral quantification (both by qPCR and cell-culture viral ... -
Inhibition of nervous necrosis virus replication by Shewanella putrefaciens Pdp11 extract
Moreno, Patricia; Álvarez-Torres, Daniel; Balebona-Accino, María del Carmen; Domínguez-Maqueda, Marta; Moriñigo-Gutiérrez, Miguel Ángel; Béjar-Alvarado, Julia; Alonso-Sánchez, María del Carmen; García-Rosado, Esther[et al.] (Elsevier, 2023)One of the most relevant infectious diseases affecting farmed fish is the viral encephalopathy and retinopathy, caused by the nervous necrosis virus (NNV). The two commercial vaccines available against this virus have been ... -
Juvenile gilthead sea bream immune response against RGNNV or RGNNV/SJNNV infections
Gémez-Mata, Juan; Moreno Garcia, Patricia; Álvarez-Torres, Daniel; García-Rosado, Esther; Béjar-Alvarado, Julia; Alonso-Sánchez, María del Carmen[et al.] (Sociedad Española de Virología, 2024-09-02)Viral nervous necrosis is one of the main threats for the aquaculture. It is caused by the nervous necrosis virus (NNV), with a genome composed of two positive-sense, ssRNA segments: RNA1, encoding the viral polymerase; ... -
Nodavirus-host interplay: what we know and what is next.
Moreno, Patricia; Álvarez-Torres, Daniel; García-Rosado, Esther; Alonso-Sánchez, María del Carmen; Béjar-Alvarado, Julia (2024)Nervous necrosis virus (NNV) is a bisegmented ssRNA virus that is classified into four species: SJNNV, RGNNV, TPNNV and BFNNV. NNV causes viral nervous necrosis, a disease that affects farmed fish worldwide and in the ... -
Papel del inmunogen isg15 de lubina (Dicentrarchus labrax) en las infecciones por betanodavirus
Moreno, Patricia; García-Rosado, Esther; Borrego-García, Juan José; Alonso-Sánchez, María del Carmen (Universidad de Oviedo, 2016)En peces, al igual que en vertebrados superiores, la respuesta antiviral innata está mediada por el sistema interferón tipo I (IFN I), que actúa mediante la activación de genes denominados isg (interferon-stimulated genes), ... -
Polisacáridos de Porphyridium cruentum presentan actividad antiviral diferencial frente a infecciones causadas de VHSV y VNN
Moreno Garcia, Patricia; Parra-Riofrio, Geovanna; Abdala-Díaz, Roberto Teófilo; García-Rosado, Esther; Uribe-Tapia, Eduardo; Alonso-Sánchez, María del Carmen; Béjar-Alvarado, Julia[et al.] (Sociedad Española de Microbiología, 2021)Los microorganismos del medio marino constituyen una importante fuente de compuestos cuya utilización en la prevención y/o tratamiento de enfermedades de etiología viral está siendo sugerida en los últimos años. En concreto, ... -
RRGNNV capsid protein amino acids 247 and 270 are involved in betanodavirus virulence to European sea bass (Dicentrarchus labrax)
Moreno, Patricia; Souto, Sandra; Leiva-Rebollo, Rocío; García-Rosado, Esther; Borrego-García, Juan José; Bandín Matos, Isabel; Alonso-Sánchez, María del Carmen[et al.] (2019-09-18)Recombinant RGNNV viruses harbouring SJNNV-type amino acids at positions 247 and/or 270 (Mut247Dl965, Mut270Dl965, Mut247+270Dl965) were generated by reverse genetics. The effect of these modifications on viral replication ... -
Senegalese sole (Solea senegalensis) ISG15: molecular characterization and in vivo interplay with viral infections
Álvarez-Torres, Daniel; Podadera, Ana María; Bandín Matos, Isabel; Béjar-Alvarado, Julia; García-Rosado, Esther; Alonso-Sánchez, María del Carmen[et al.] (2015-09-17)The interferon-stimulated gene 15 (Isg15) is strongly induced by type I interferon (IFN I), viral infection, and double-stranded RNA (poly I:C) in several fish species, suggesting that Isg15 protein could play a key role ... -
Senegalese sole transcriptomic profiles in response to different betanodavirus RGNNV/SJNNV reassortant strains
Labella Vera, Alejandro Manuel; Borrego-García, Juan José; Manchado, Manuel; Bandín Matos, Isabel; Castro-López, María Dolores; Alonso-Sánchez, María del Carmen; García-Rosado, Esther[et al.] (2017)Betanodaviruses are the causative agents of viral nervous necrosis (VNN), a disease that has been reported in more than 40 marine and freshwater fish species worldwide, including Senegalese sole (Solea senegalensis). Based ... -
Setting out zebrafish (Danio rerio) as a model to study nervous necrosis virus-host interaction.
Moreno-García, Patricia; Álvarez-Torres, Daniel; Frétaud, Maxence; Mehraz, Manon; Langevin, Christelle; Béjar-Alvarado, Julia; Alonso-Sánchez, María del Carmen[et al.] (2023)Viral nervous necrosis is responsible for important economic losses in aquaculture facilities. The causative agent is the nervous necrosis virus (NNV). Four NNV species have been described, although only RGNNV and SJNNV ... -
Shewanella putrefaciens Pdp11 extracts promote European sea bass resistance against RGNNV infection.
Moreno-García, Patricia; Álvarez-Torres, Daniel; Gémez-Mata, Juan; Balebona-Accino, María del Carmen; Domínguez-Maqueda, Marta; Cerezo-Domínguez, Ana Isabel; Moriñigo-Gutiérrez, Miguel Ángel; Béjar-Alvarado, Julia; García-Rosado, Esther; Alonso-Sánchez, María del Carmen[et al.] (2024)The viral nervous necrosis (VNN) is a neurotropic disease affecting different fish species, resulting in high mortality rates. The causal agent is the nervous necrosis virus (NNV), belonging to the Betanodavirus genus, ... -
Shewanella putrefaciens Pdp11 extracts protect against betanodavirus infection.
Moreno-García, Patricia; Álvarez-Torres, Daniel; Balebona-Accino, María del Carmen; Moriñigo-Gutiérrez, Miguel Ángel; Béjar-Alvarado, Julia; Alonso-Sánchez, María del Carmen; García-Rosado, Esther[et al.] (2023)Viral nervous necrosis is caused by the nervous necrosis virus (Betanodavirus genus), a naked virus with two positive-sense RNA segments. Betanodaviruses are classified into four species, being RGNNV predominant in the ... -
El sistema del interferón tipo I protege a juveniles de lenguado senegalés (Solea senegalensis) frente a la infección por VHSV
Álvarez-Torres, Daniel; Podadera, AM; Vieytes, Lisandro P; Souto, S; Bandin, S; Béjar-Alvarado, Julia; Alonso-Sánchez, María del Carmen; García-Rosado, Esther[et al.] (2014-09-25)El lenguado senegalés (Solea senegalensis) es susceptible a la infección por el Virus de la Septicemia Hemorrágica Viral (VHSV) bajo condiciones experimentales. El objetivo de este trabajo es determinar el papel del sistema ...