Listar por departamento/instituto "Especialidades Quirúrgicas, Bioquímica e Inmunología"
Mostrando ítems 1-20 de 193
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A metagenome-wide association study of HIV disease progression in HIV controllers.
Real-Navarrete, Luis Miguel
; Saéz, María E; Corma-Gómez, Anaïs; González-Pérez, Antonio; Thorball, Christian; Ruiz, Rocío; Jiménez-León, María Reyes; González-Serna, Alejandro; Gasca-Capote, Carmen; Bravo-Romero, María José; Royo-Sánchez-Palencia, José Luis; Pérez-Gómez, Alberto; Camacho-Sojo, María Inés; Gallego, Isabel; Joana, Vitalle; Bachiller, Sara; Gutierrez-Valencia, Alicia; Vidal, Francisco; Fellay, Jacques; Lichterfeld, Mathias; Ruiz-Mateos, Ezequiel[et al.] (Elsevier, 2023)
Some HIV controllers experience immunologic progression with CD4+ T cell decline. We aimed to identify genetic factors associated with CD4+ T cell lost in HIV controllers. A total of 561 HIV controllers were included, 442 ... -
Acquisition resistance to bleomycin deregulates HSP77 and HSP60 proteins in response to stress
Burgos-Molina, Antonio Manuel; Alamilla Presuel, Juan Carlos; Mercado-Sáenz, Silvia; González Vidal, Alejandro; Ruiz-Gómez, Miguel José (Aseica, 2022)
The HSP77 and HSP60 protein overexpression is implicated in bleomycin resistance. The resistant adquisition to antineoplastic drugs deregulate proteins involved in response to stress factors. -
Age related changes in the bone microstructure in patients with femoral neck fractures.
Sánchez-Siles, Juan Manuel; Tamimi-Mariño, Iskandar Ahmad; Rodriguez Gonzalez Cortes, Arthur; Ackerman, Jerome L; González-Quevedo, David; Guerado-Parra, Enrique; García, Angel; Yaghoubi, Farid; Abdallah, Mohamed Nur; Eimar, Hazem; Laurenti, Marco; Al-Subaie, Ahmed; Tamimi, Faleh[et al.] (Elsevier, 2020-02-16)
Background The objective of this study was to analyze the correlation between various bone structural features and age. Study Design & Methods A total of 29 consecutive patients who suffered an intracapsular hip fracture ... -
An intragenic duplication within SIRPβ1 shows a dual effect over Alzheimer’s disease cognitive decline altering the microglial response.
García-Alberca, JM; de Rojas, I; Sánchez-Mejías, Elisabeth; Garrido-Martín, D; Gonzalez-Palma, L; Jimenez, S; Pino-Angeles, A; Cruz-Gamero, JM; Mendoza, S; Alarcón-Martín, E; Muñoz-Castro, Clara; Real-Navarrete, Luis Miguel; Tena, Juan J.; Polvillo, R; Govantes, F; Lopez, A; Royo-Aguado, JL; Navarro, V; Gonzalez, I; Ruiz, M; Reyes-Engel, Armando; Gris, E; Bravo, MJ; Lopez-Gutierrez, L; Mejías-Ortega, Marina; De la Guía, María Paz; López de la Rica, M; Ocejo, Olga; Torrecilla, J; Zafra, C; Nieto, MD; Urbano, C; Jiménez-Sánchez, R; Pareja, N; Luque, M; García-Peralta, María; Carrillejo, Rosario; Furniet, MDC; Rueda, L; Sánchez-Fernández, A; Mancilla, T; Peña, I; García-Casares, N; Moreno-Grau, S; Hernández, I; Montrreal, L; Quintela, I; González-Pérez, A; Calero, M; Franco-Macías, Emilio; Macías, J; Menéndez-González, M; Frank-García, A; Huerto Vilas, R; Diez-Fairen, M; Lage, C; García-Madrona, S; García-González, P; Valero, S; Sotolongo-Grau, O; Pérez-Cordón, A; Rábano, A; Arias Pastor, A; Pastor, AB; Espinosa, A; Corma-Gómez, A; Martín Montes, A; Sanabria, A; Martínez Rodríguez, C; Buiza-Rueda, D; Rodriguez-Rodriguez, E; Ortega, G; Alvarez, I; Rosas Allende, I; Pineda, JA; Rosende-Roca, M; Bernal Sánchez-Arjona, M; Fernández-Fuertes, M; Alegret, M; Roberto, N; Del Ser, T; Garcia-Ribas, G; Sánchez-Juan, P; Pastor, P; Piñol-Ripoll, G; Bullido, MJ; Álvarez, V; Mir, P; Medina, M; Marquié, M; Sáez, ME; Carracedo, A; Laplana, M; Tomas-Gallardo, L; Orellana, A; Tárraga, LL; Boada, M; Fibla Palazon, J; Vitorica Ferrández, Javier; Ruiz, A; Guigo, R; Gutiérrez-Pérez, Antonia; Royo-Sánchez-Palencia, José Luis[et al.] (SAGE, 2024)
Microglia play an important role in the maintenance of brain homeostasis, and microglial dysfunction plays a causative role in Alzheimer disease pathogenesis. Here we focus on the signal regulatory protein SIRPβ1, a surface ... -
Análisis comparativo de los resultados de cirugía laparoscópica vs cirugía robótica en cáncer rectal electivo
(UMA Editorial, 2021-12-16)Introducción: La cirugía laparoscópica asistida por robot intenta facilitar la cirugía rectal en el estrecho espacio de la pelvis. El objetivo de este estudio es comparar los resultados de la cirugía robótica versus la ... -
Análisis de las alteraciones bioquímicas y hemodinámicas generadas en las técnicas abierta y cerrada de la quimioterapia intraperitoneal hipertérmica en el tratamiento de la carcinomatosis peritoneal de origen colorrectal.
(UMA Editorial, 2017-07-13)El cáncer colorrectal representa globalmente la tercera neoplasia más frecuente, siendo la cuarta causa de mortalidad relacionada con el cáncer. Constituye un problema de salud pública en los países occidentales al ser la ... -
Análisis genético del dimorfismo secual en el eje de folatos-homocisteína en una población tratada con ácido fólico
(UMA Editorial, 2015)Bajo el término folatos se agrupan los derivados del ácido fólico, una familia de vitaminas con actividad biológica equivalente. Su capacidad de transporte de grupos monocarbonados activos en su estructura les confiere ... -
Analysis of Immunotherapy in hepatocellular carcinoma
Burgos-Molina, Antonio Manuel; Alamilla Presuel, Juan Carlos; González Vidal, Alejandro; Ruiz-Gómez, Miguel José (Aseica, 2022)
One reason immunotherapy is important for Hepatocellular carcinoma, it’s because there are many immune cells in that organ. Because HCC is very aggressive, immunotherapy must be applied correctly. There are a lot of ... -
Analysis of Immunotherapy in Lung cancer
Burgos-Molina, Antonio Manuel; Alamilla Presuel, Juan Carlos; González Vidal, Alejandro; Ruiz-Gómez, Miguel José (Aseica, 2022)
There are many ways of immunotherapy for lung cancer, and that includes the use of drugs, molecular treatment, and even the combination with radiotherapy. But also, it’s important to investigate in the future the adverse ... -
Analysis of Immunotherapy in ovarian cancer
Burgos-Molina, Antonio Manuel; Alamilla Presuel, Juan Carlos; González Vidal, Alejandro; Ruiz-Gómez, Miguel José (Aseica, 2022)
There are many Immunotherapy methods in ovarian cancer. Even the immune cells themselves can be part of the immunotherapy. But also at molecular level, the immunotherapy can be applied, like maintaining damage in DNA or ... -
Analysis of Immunotherapy in Triple negative breast cancer
Burgos-Molina, Antonio Manuel; Alamilla Presuel, Juan Carlos; González Vidal, Alejandro; Ruiz-Gómez, Miguel José (Aseica, 2022)
TNBC cancer is complicated, most is about PD-L1 mechanism. Too many kinds of immunotherapy have been developed to treat TNCB. Nowadays, is complicated a fast and 100% accurate treatment for TNBC, because of cancer complications ... -
Anticlusterin treatment of breast cancer cells increases the sensitivities of chemotherapy and tamoxifen and counteracts the inhibitory action of dexamethasone on chemotherapy-induced cytotoxicity
Redondo-Bautista, Maximino; Téllez-Santana, Teresa; Roldán Cardenete, María José; Serrano-Garballo, Alfonso; García Aranda, Marilina; Gleave, Martin E; Hortas Nieto, María Luisa; Morell Ocaña, Miguel[et al.] (BMC Springer Nature, 2007-12-13)
Introduction: Overexpression of the apoptosis-related protein clusterin is associated with breast cancer development and tumor progression. We describe the use of clusterin-specific antisense oligonucleotides and antibodies ... -
Aplicabilidad de scores pronósticos de mortalidad postquirúrgica en pacientes mayores de 60 años que requieren cirugía abdominal urgente
(UMA Editorial, 2017-07-11)INTRODUCCIÓN Y JUSTIFICACIÓN DEL ESTUDIO: El envejecimiento de la población occidental resulta evidente y tiene un origen multifactorial basado en cambios socioeconómicos, avances de la ciencia médica y políticas de ... -
Association between metabolic status and the methylation level of genes involved in metabolic disorders and obesity
Castellano-Castillo, Daniel; Moreno-Indias, Isabel; Picon-Cesar, María José; Garcia-Aleman, Jorge; Macias-Gonzalez, Manuel; Tinahones-Madueño, Francisco José; Queipo-Ortuño, María Isabel; Cardona-Díaz, Fernando[et al.] (2014-08-01)
Objectives: DNA methylation is one of the epigenetic mechanims to control gene expression, and it is believed to be modulated by environmental and nutritional factors. Thus, epigenetics provides a mechanism which may explain ... -
AURKA, BIRC5 and PLK1 as potential biomarkers of response in radiation-resistant colorectal cancer
Burgos-Molina, Antonio Manuel; Rodríguez-García, M.; González-Vidal, A.; Mercado-Sáenz, Silvia; Ruiz-Gómez, Miguel José (ASEICA, 2024-11)
The study demonstrated that AURKA, BIRC5 and PLK1 proteins are hyper-expressed in patients affected by colon and rectum adenocarcinoma resistant to radiotherapy. The validation of the expression levels in patient samples ... -
BAGUA vs procedimientos restrictivos para DM2.
(2014-06-12)Se valoran las ventajas del BAGUA sobre los procedimientos restrictivos, bana y manga gástrica, enfocados a la diabesidad y DM2. Se describe la técnica quirúrgica del BAGUA, con sus beneficios, desventajas y la remisión ... -
Beneficial interactions between the microbiota and the host increase immunity for a better response to treatment of cancer patients
Burgos-Molina, Antonio Manuel; González Vidal, Alejandro; Mercado-Sáenz, Silvia; Alamilla Presuel, Juan Carlos; Ruiz-Gómez, Miguel José (2022)
Numerous beneficial interactions between microbiota and host contribute to produce nutrients, metabolites, immunoglobulins and an increase in lymphocytes. The correct colonization of the intestine by microbiota induces a ... -
Bypass Gástrico BII.
(2014-06-12)Hay varias técnicas de bypass gástrico para la reducción del peso, la cual se decide dependiendo de la historia, hábitos dietéticos, evaluación psicológica, estado médico, reflujo gastroesofágico, diabetes. El bypass ... -
Calcium Homeostasis in the Development of Resistant Breast Tumors.
Martin-García, Desirée; Téllez-Santana, Teresa; Redondo-Bautista, Maximino; García Aranda, Marilina (MDPI, 2023-05-23)
Cancer is one of the main health problems worldwide. Only in 2020, this disease caused more than 19 million new cases and almost 10 million deaths, with breast cancer being the most diagnosed worldwide. Today, despite ... -
¿Cambio de paradigma desde el bypass gástrico Roux-en-Y al (mini) bypass gástrico debido a problemas de glucosa?
(2014-06-12)El bypass gástrico Roux-en-Y funciona de la siguiente manera sobre la diabetes mellitus tipo 2: En obesos mórbidos la diabetes tipo2 inicia con la presencia de resistencia a la insulina con un incremento del péptido C, o ...