Listar por tema "GAL(1-15)"
Mostrando ítems 1-7 de 7
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A Role For Galanin N-Terminal Fragment (1-15) In Anxiety And Depression in rats
Millon-Peñuela, Carmelo
; Flores-Burgess, Antonio; Narváez, Manuel; Borroto-Escuela, Dasiel; Santin-Nuñez, Luis Javier; Narváez, José Ángel; Fuxe, Kjell; Díaz-Cabiale, Zaida[et al.] (2015-10-06)
Galanin (GAL) is involved in several functions including mood regulation. The GAL N-terminal fragment (1-15) [GAL(1-15)] also participates at central level and a differential role of GAL(1-15) compared with GAL has been ... -
The effect of Galanin N-Terminal fragment (1-15) in anhedonia: Involvement of the dopaminergic mesolimbic system.
Millon-Peñuela, Carmelo; Flores-Burgess, Antonio; Gago-Calderon, Belen; Garcia-Duran, Laura; Cantero-García, Noelia; Alén, Francisco; Orio, Laura; Narváez, José Ángel; Fuxe, Kjell; Santin-Nuñez, Luis Javier; Díaz-Cabiale, Zaida[et al.] (2019-11-18)
The Galanin N-terminal fragment (1-15) [GAL(1-15)] induces depressant- and anxiogenic-like actions in behavioral tests and these effects were significantly stronger than the ones induced by Galanin. Since anhedonia is a ... -
GAL(1-15) induces a depression and anxiogenic effect trough GALR1/GALR2 heteroreceptor: siRNA GALR1/GALR2 knockdown rats
Millon-Peñuela, Carmelo; Flores-Burgess, Antonio; Narváez, Manuel; Borroto-Escuela, Dasiel; Santin-Nuñez, Luis Javier; Parrado-Romero, Concepcion; Narváez, José Ángel; Fuxe, Kjell; Díaz-Cabiale, Zaida[et al.] (2015-10-06)
The Galanin N-terminal fragment (1-15) [GAL(1-15)] induces depressant- and anxiogenic- like actions. In this work, we have studied the role of GALR2 and GALR1 on the effects of GAL(1-15) in the Forced Swimming Test (FST) ... -
Galanin N-Terminal fragment (1-15) enhances the antidepressant effects of the 5-HT1A receptor agonist 8-OH-DPAT in the Forced Swimming Test.
Millon-Peñuela, Carmelo; Flores-Burgess, Antonio; Narváez, Manuel; Borroto-Escuela, Dasiel; Santin-Nuñez, Luis Javier; Gago-Calderon, Belen; Parrado-Romero, Concepcion; Gomez de Travecedo, Isabel; Narváez, José Ángel; Fuxe, Kjell; Díaz-Cabiale, Zaida[et al.] (2016-07-27)
Galanin and Galanin (1-15) [GAL(1-15)] are implicated in anxiety- and depression related behaviors. Moreover, Galanin modulates 5-HT1A receptor (5-HT1AR) function at autorreceptor and postsynaptic level in the brain. In ... -
GALR1/GALR2 Knockdown rats block the Depression and Anxiogenic effects induced by GAL(1-15): The Heterodimer GALR1/GALR2 as a target of GAL(1-15).
Millon-Peñuela, Carmelo; Flores-Burgess, Antonio; Narváez, Manuel; Borroto-Escuela, Dasiel; Santin-Nuñez, Luis Javier; Parrado-Romero, Concepcion; Narváez, José Ángel; Fuxe, Kjell; Díaz-Cabiale, Zaida[et al.] (2015-10-06)
The Galanin N-terminal fragment (1-15) [GAL(1-15)] induces depressant- and anxiogenic- like actions. In this work, we have studied the role of GALR2 and GALR1 on the effects of GAL(1-15) in the Forced Swimming Test (FST) ... -
Papel del fragmento N-terminal (1-15) de la Galanina en depresión: interacciones con la Fluoxetina
Flores-Burgess, Antonio (UMA Editorial, 2019-11)
La Galanina (GAL) es un péptido ampliamente distribuido en el SNC (Tatemoto et al., 1983) que media sus acciones a través de tres receptores. GALR1 y GALR3 activan principalmente las proteínas G inhibitorias Gi/Go y GALR2 ... -
Role of the 5-HT1A receptors in the effect of Galanin(1-15) on Fluoxetine-mediated action in the forced swimming test
Flores-Burgess, Antonio; Santin-Nuñez, Luis Javier; Díaz-Cabiale, Zaida; Millon-Peñuela, Carmelo; Narváez, Manuel; Borroto-Escuela, Dasiel O.; Narváez, José Ángel; Fuxe, Kjell[et al.] (2018-06-28)
Galanin N-terminal fragment (1-15) [GAL(1-15)] modulates the antidepressant effects induced by the 5-HT1A receptor (5-HT1AR) agonist in the forced swimming test (FST) and the binding characteristics and mRNA levels of ...