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dc.contributor.authorSabarit, Blanca
dc.contributor.authorArroyo-Mateos, Manuel
dc.contributor.authorSánchez-Durán, Miguel A.
dc.contributor.authorRodriguez-Bejarano, Eduardo 
dc.date.accessioned2015-10-21T12:16:10Z
dc.date.available2015-10-21T12:16:10Z
dc.date.created2015
dc.date.issued2015-10-21
dc.identifier.urihttp://hdl.handle.net/10630/10558
dc.description.abstractRep is a multifunctional protein essential for replication of geminivirus that interferes with the sumoylation of a key protein in the DNA replication, PCNA (Proliferating Cell Nuclear Antigen). It is known that Rep is capable of interacting with a plethora of plant proteins, including PCNA. Despite the biological significance remains unknown, it’s thought that this interaction should play a key role for generating new copies of the virus genome. Therefore, in order to characterize this interaction, we study which lysines are sumoylated in tomato PCNA (SlPCNA). Considering conservation, location and presence of sumoylation domain criteria, we have identified some candidate lysines and studied how its mutation affects this protein sumoylation in Escherichia coli assays. Finally, we plan to confirm and characterize the Rep interference on SlPCNA sumoylation and determine if this interference occurs in planta.es_ES
dc.description.sponsorshipUniversidad de Málaga. Campus de Excelencia Internacional Andalucía Tech.es_ES
dc.language.isoenges_ES
dc.rightsinfo:eu-repo/semantics/openAccesses_ES
dc.subjectVirus fitopatógenoses_ES
dc.subject.otherRepes_ES
dc.subject.otherPCNAes_ES
dc.subject.otherGeminiviruses_ES
dc.subject.otherSumoylationes_ES
dc.titleGeminiviral protein Rep interferes in PCNA sumoylationes_ES
dc.typeinfo:eu-repo/semantics/conferenceObjectes_ES
dc.centroFacultad de Cienciases_ES
dc.relation.eventtitleWorkshop. Practical course on ubiquitin and ubiquitin-like proteinses_ES
dc.relation.eventplaceFrankfurtes_ES
dc.relation.eventdate05/10/2015es_ES
dc.cclicenseby-nc-ndes_ES


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