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dc.contributor.authorMesa-Antunez, Pablo
dc.contributor.authorCollado, Daniel 
dc.contributor.authorVida-Pol, Yolanda 
dc.contributor.authorNajera-Albendin, Francisco 
dc.contributor.authorFernandez, Tahia
dc.contributor.authorTorres, Maria Jose
dc.contributor.authorPerez-Inestrosa, Ezequiel
dc.date.accessioned2016-06-28T07:08:02Z
dc.date.available2016-06-28T07:08:02Z
dc.date.created2016
dc.date.issued2016
dc.identifier.urihttp://hdl.handle.net/10630/11676
dc.description.abstractA new fluorescent dendrimeric antigen (DeAn) based on a dendron with amoxicilloyl terminal groups has been synthetized. The synthesis implies a novel class of all-aliphatic polyamide dendrimer (BisAminoalkylPolyAmide Dendrimers, or BAPAD).[1] The introduction of a cystamine core allows the incorporation of this dendrons into a 1,8-naphthalimide fluorofore functionalized with a maleimide group. The fluorescence properties of this DeAn has been studied and compared with the properties of an equivalent dendron possessing amino-terminal groups. This DeAn has been used as a synthetic antigen in a biomedical assay that tests the amoxicillin sensitivity of dendritic cells (DC) from tolerant and allergic patients.es_ES
dc.description.sponsorshipUniversidad de Málaga. Campus de Excelencia Internacional Andalucía Tech.es_ES
dc.language.isospaes_ES
dc.publisherServicio de Publicaciones de la Universidad de Huelvaes_ES
dc.rightsinfo:eu-repo/semantics/openAccesses_ES
dc.subjectBiomoléculases_ES
dc.subjectBiopolímeroses_ES
dc.subject.otherDendrimerses_ES
dc.subject.otherFluorescent probees_ES
dc.subject.otherDendritic celles_ES
dc.subject.otherDendrimeric antigenes_ES
dc.titleSynthesis of fluorescent dendrimeric antigen efficiently internalized by human dendritic cellses_ES
dc.typeinfo:eu-repo/semantics/conferenceObjectes_ES
dc.centroFacultad de Cienciases_ES
dc.relation.eventtitleXXVI Reunión Bienal de Química Orgánicaes_ES
dc.relation.eventplacePunta Umbría (Huelva, Spain)es_ES
dc.relation.eventdate06/2016es_ES
dc.identifier.orcidhttp://orcid.org/orcid.org/0000-0002-1635-5514es_ES
dc.cclicenseby-nc-ndes_ES


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