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dc.contributor.authorCollado-Martín, Daniel 
dc.date.accessioned2016-09-13T11:21:29Z
dc.date.available2016-09-13T11:21:29Z
dc.date.created2016
dc.date.issued2016-09-13
dc.identifier.urihttp://hdl.handle.net/10630/11995
dc.description.abstractFluorescent probes are essential tools for studying biological systems. The last decade has witnessed particular interest in the development of two-photon excitable probes, due to their advantageous features in tissue imaging compared to the corresponding one-photon probes [1]. Recently, we have designed and synthetized an aminonaphthalimide–BODIPY derivative as energy transfer cassettes and were found to show very fast and efficient BODIPY fluorescence sensitization [2]. This was observed upon one- and two-photon excitation, which extends the application range of the investigated bichromophoric dyads in terms of accessible excitation wavelengths. In order to increase the two-photon absorption of the system aminonaphthalimide fluorophore was replace with a Prodan analog (BODIPY dyad 1), which presents found a variety of applications as probes and labels in biology [3]. The two-photon absorption cross-section  of the dyads is significantly incremented by the presence of the 6-acetyl-2-naphthylamine donor group. The emission maximum of a BODIPY fluorophore can significantly be red-shifted in comparison to their precursors by conjugation with aromatic aldehydes. [4] We use a synthetic strategy to obtain BODIPY dyad 2 that incorporates an imidazole ring. This molecule can be used in biological media as a near-neutral pH indicator based on one- and two-photon excitable BODIPY acceptor.es_ES
dc.description.sponsorshipUniversidad de Málaga. Campus de Excelencia Internacional Andalucía Tech.es_ES
dc.language.isoenges_ES
dc.rightsinfo:eu-repo/semantics/openAccesses_ES
dc.subjectFotoquímicaes_ES
dc.subjectFotobioquímicaes_ES
dc.subject.otherPhotochemistryes_ES
dc.subject.otherEnergy transferes_ES
dc.titleNew bodipy dyads for two-photons fluorescence imaging in cellses_ES
dc.typeinfo:eu-repo/semantics/conferenceObjectes_ES
dc.centroFacultad de Cienciases_ES
dc.relation.eventtitleVth Spanish-Portuguese Workshop on Photochemistryes_ES
dc.relation.eventplaceToledoes_ES
dc.relation.eventdate07/09/2016es_ES
dc.identifier.orcidhttp://orcid.org/0000-0002-8155-7112es_ES
dc.cclicenseby-nc-ndes_ES


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