Mostrar el registro sencillo del ítem

dc.contributor.authorAguilera-Cobos, Lorena
dc.contributor.authorSeoane, Pedro
dc.contributor.authorGonzalo Claros, M.
dc.contributor.authorMoriñigo-Gutierrez, Miguel Angel 
dc.contributor.authorBalebona-Accino, Maria del Carmen 
dc.contributor.authorNúñez-Serrano, Rafael
dc.contributor.authorCórdoba, José
dc.contributor.authorTapia-Paniagua, Silvana
dc.date.accessioned2018-12-10T12:50:05Z
dc.date.available2018-12-10T12:50:05Z
dc.date.created2018
dc.date.issued2018-12-10
dc.identifier.urihttps://hdl.handle.net/10630/17030
dc.description.abstractThe study of probiotic microorganisms is very interesting in the aquaculture field. Administration of live microorganisms in adequate amounts confers some benefits to the host (Kechagia et al. 2013). Even if Shewanella putrafaciens include pathogens and saprophytic strains related to fish spoilage and fish infection (Esteve, Merchán, and Alcaide 2016). The Pdp11 strain of Shewanella putrefaciens has been proved to provide beneficial effects in Sparus aurata (Chabrillón et al. 2005) and Solea senegalensis (Rodrigáñez et al. 2008). Studies focused on Pdp11 could hed light on the origin of this probiotic character. We have designed a bioinformatic workflow to detect transposons in the newly sequenced Pdp11 genome (Tapia-Paniagua et al, in press). Their presence interrupting genes account for a contribution to its probiotic character due to the lost of virulence or the gain of probiotic effect. The workflow was developed in Ruby programming language and provides: the genomic localisation of known transposons, host coding regions disrupted by complete transposons or their repeated insertion sequences, and transposons and coding regions disrupted identifiers, to stablish the putative functions of Pdp11 that could be affect by the transposons disruption. These results would support new possible hypothesis about the Pdp11 probiotic character since 14 coding regions related to S. putrefaciens were disrupted by transposons, 4 of which are directly involved in pathogenic mechanisms. This work was supported by co-funding by the European Union through the European Regional Development Fund (ERDF) 2014-2020 "Programa Operativo de Crecimiento Inteligente" together with Spanish AEI "Agencia Estatal de Investigación" to grants RTA2013-00068-C03, AGL2017-83370-C3-3-R and RTA2017-00054-C03-03.en_US
dc.description.sponsorshipUniversidad de Málaga. Campus de Excelencia Internacional Andalucía Tech.en_US
dc.language.isoengen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.subjectTransposonesen_US
dc.subject.otherTransposonsen_US
dc.subject.otherWorkflowen_US
dc.subject.otherProbioticsen_US
dc.subject.otherShewanellaen_US
dc.titleDetection of transposons modifying genome background in probioticsen_US
dc.typeinfo:eu-repo/semantics/conferenceObjecten_US
dc.centroFacultad de Cienciasen_US
dc.relation.eventtitleXIV Symposium on Bioinformaticsen_US
dc.relation.eventplaceGranada - Españaen_US
dc.relation.eventdate11/2018en_US
dc.rights.ccAttribution-NonCommercial-NoDerivatives 4.0 Internacional*


Ficheros en el ítem

Este ítem aparece en la(s) siguiente(s) colección(ones)

Mostrar el registro sencillo del ítem

Attribution-NonCommercial-NoDerivatives 4.0 Internacional
Excepto si se señala otra cosa, la licencia del ítem se describe como Attribution-NonCommercial-NoDerivatives 4.0 Internacional