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dc.contributor.authorORTEGA RODRIGUEZ, ALICIA
dc.contributor.authorPORRAS ALCALA, CRISTINA
dc.contributor.authorContreras-Cáceres, Rafael
dc.contributor.authorLópez-Romero, Juan Manuel 
dc.contributor.authorMELGUIZO, CONSOLACION
dc.contributor.authorPRADOS, JOSE CARLOS
dc.date.accessioned2019-05-15T08:31:48Z
dc.date.available2019-05-15T08:31:48Z
dc.date.created2019
dc.date.issued2019-05-15
dc.identifier.urihttps://hdl.handle.net/10630/17659
dc.description.abstractThe development and identification of new antitumoral has become a research area of great interest and maximum priority due to secondary effects of current antitumoral and the appearance of tumours resistant to these agents. Marine sponges corresponding to the Jaspidae family have proved to be a prolific source of bioactive natural products. Among these, the Bengamides have showed an important biological profile, including antitumor, antibiotic and anthelmintic properties. Due to the interest of theses natural products, we describe a study directed towards the total synthesis of this class of compounds. Then we encapsulate Bengamides in temperature sensitive microgels with a magnetic core. Magnetic nanoparticles (Fe3O 4) were prepared by coprecipitation method and the surface was functionalized by acrylic acid. Polymer poly(N-isopropylacrylamide) (PNIPAM) were grown by free radical polymerization in presence of cross-liker and initiator.en_US
dc.description.sponsorshipUniversidad de Málaga. Campus de Excelencia Internacional Andalucía Techen_US
dc.language.isoengen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectNanoparticulas magneticasen_US
dc.subjectEsponjas marinas - Microbiologíaen_US
dc.subject.otherBengamides, Jaspidae, Antitumoral, total synthesis, magnetic nanoparticles.en_US
dc.titleSynthesis of New Analogues of the Bengamides to encapsulate in magnetic nanoparticlesen_US
dc.typeinfo:eu-repo/semantics/otheren_US
dc.centroFacultad de Cienciasen_US
dc.relation.eventtitleIWBBIO19en_US
dc.relation.eventplaceGRANADA, ESPAÑAen_US
dc.relation.eventdateMAYO 2019en_US


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