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dc.contributor.authorLópez-Pagan, Nieves
dc.contributor.authorSánchez-Romero, María Antonia
dc.contributor.authorRufián, José S.
dc.contributor.authorAussel, Laurant
dc.contributor.authorGovantes, Fernando
dc.contributor.authorRuiz-Albert, Javier
dc.date.accessioned2019-07-29T06:35:07Z
dc.date.available2019-07-29T06:35:07Z
dc.date.created2019
dc.date.issued2019-07-29
dc.identifier.urihttps://hdl.handle.net/10630/18164
dc.description.abstractThe notion of isogenic bacterial populations displaying phenotypic differences is widely accepted today. A particular case of phenotypic heterogeneity is bistability. Bistability occurs when bacterial population splits into two subpopulations showing distinct phenotypes. Phenotypic heterogeneity can allow some individuals to survive sudden environmental changes (risk-spreading) and can also lead to the cooperation (division of labour) between individuals. The relevance of this process has been highlighted in some animal pathogens, nevertheless, little is known about the occurrence or impact of these processes in the adaptation of bacteria to non-animal hosts. Pseudomonas syringae is a plant-pathogenic bacterium whose virulence depend of the T3SS expression. We have reported that T3SS expression is bistable in hrp-induction medium. This bistability generates two subpopulations, that show differences in virulence. Flagella is also an important virulence determinant for Pseudomonas syringae colonization. Here, we show how flagella expression also displays markedly phenotypic heterogeneity during growth within the plant. Although subpopulations displaying flagONT3SSON and flagOFFT3SSOFF can be identified within the plant, we provide evidence of cross regulation between T3SS and flagella expression at the individual cell level and propose phenotypic heterogeneity as an adaptative value for Pseudomonas adaptation to the plant host.en_US
dc.description.sponsorshipUniversidad de Málaga. Campus de Excelencia Internacional Andalucía Tech.en_US
dc.language.isoengen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.titlePhenotypic heterogeneity in Pseudomonas syringaeen_US
dc.typeinfo:eu-repo/semantics/conferenceObjecten_US
dc.centroFacultad de Cienciasen_US
dc.relation.eventtitleXVIII Congress IS-MPMI 2019en_US
dc.relation.eventplaceGlasgow, Escocia, Gran Bretañaen_US
dc.relation.eventdate14-18 Julio, 2019en_US
dc.rights.ccAttribution-NonCommercial-NoDerivatives 4.0 Internacional*
dc.rights.ccAttribution-NonCommercial-NoDerivatives 4.0 Internacional*


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Attribution-NonCommercial-NoDerivatives 4.0 Internacional
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