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dc.contributor.authorPorras Alcalá, Cristina
dc.date.accessioned2019-09-16T08:02:21Z
dc.date.available2019-09-16T08:02:21Z
dc.date.created2019
dc.date.issued2019-09-16
dc.identifier.urihttps://hdl.handle.net/10630/18349
dc.description.abstractThe development and identification of new antitumoral drugs has become a research area of great interest and maximum priority. Firstly, to overcome the secondary effects frequently shown by current antitumorals and, secondly, to prevent the appearance of tumours resistance to these agents. Marine sponges corresponding to the Jaspidae family have proved to be a prolific source of bioactive natural products. Among these, the bengamides have showed an important biological profile, including antitumor, antibiotic and anthelmintic properties. We describe here a study directed towards the total synthesis of bengamides including their encapsulation into temperature-sensitive microgels having magnetic Fe3O4 cores. Magnetic nanoparticles were prepared by the coprecipitation method and show an acrylic acid surface functionalization. We chose poly(N-isopropylacrylamide) (PNIPAM) as polymeric material, which was grown by a free radical polymerization process.en_US
dc.description.sponsorshipUniversidad de Málaga. Campus de Excelencia Internacional Andalucía Tech.en_US
dc.language.isoengen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectCáncer - Tratamientoen_US
dc.subject.otherAntitumoralen_US
dc.subject.otherBengamideen_US
dc.subject.otherSynthesisen_US
dc.titleSynthesis of new bengamide analogues and encapsulation into thermo-responsive magnetic nanoparticlesen_US
dc.typeinfo:eu-repo/semantics/conferenceObjecten_US
dc.centroFacultad de Cienciasen_US
dc.relation.eventtitleEFMC19en_US
dc.relation.eventplaceAtenasen_US
dc.relation.eventdate3 septiembre 2019en_US


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