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dc.contributor.authorÁlvarez-Mena, Ana
dc.contributor.authorAntequera-Gómez, Maria Luisa
dc.contributor.authorDíaz-Martínez, Luis
dc.contributor.authorCaro-Astorga, Joaquin
dc.contributor.authorKuipers, Oscar
dc.contributor.authorde Vicente Moreno, Antonio
dc.contributor.authorRomero, Diego
dc.date.accessioned2021-05-06T06:30:02Z
dc.date.available2021-05-06T06:30:02Z
dc.date.created2021
dc.date.issued2021-05
dc.identifier.urihttps://hdl.handle.net/10630/21658
dc.description.abstractBacillus cereus is a human pathogen responsible of many food poisoning due to the ingestion of contaminated vegetables or processed foods. The biofilm development and spore formation, are essential stages in the survival and transmission of the bacteria and hence the production of harmful toxins for the consumer. During the biofilm formation, a subpopulation is differentiated to extracellular matrix producers, mainly composed by exopolysaccharides, proteins and extracellular DNA. One of the most fascinating compounds of this matrix are the amyloid proteins, that shows a high tendency to fibrillate and have a multifunctional role in the bacterial physiology. In earlier studies it was identified that B. cereus possess two orthologues genes to the tasA gene in B. subtilis, initially described as essential in the assembly of amyloid fibers, and they were named as tasA and calY respectively. Both genes are located in the same genomic region and the deletion of each one leads to a different phenotype related with a deficient biofilm. In the case of the tasA mutant the biofilm finally detaches from the well at 72 hours, and the calY mutant shows a thinner ring phenotype in comparison with the wild type strain. Those preliminary results could indicate that TasA and CalY have different roles in the biofilm formation. The level of tasA and calY expression in the biofilm was higher than in planktonic cells, and it could be differentiated three different subpopulations: both genes are expressed, only calY or none of them. Amyloid proteins have been described as being involved in adhesion and host-colonization. A study of the dynamic of tasA gene expression show that is influenced by the type of vegetable surface.es_ES
dc.description.sponsorshipUniversidad de Málaga. Campus de Excelencia Internacional Andalucía Tech.es_ES
dc.language.isoenges_ES
dc.rightsinfo:eu-repo/semantics/openAccesses_ES
dc.subjectBacillus (Bacteria)es_ES
dc.subject.otherpatogeno humanoes_ES
dc.subject.otherBacillus cereuses_ES
dc.titleThe putative different roles of TasA and CalY in the biofilm formation of B. cereuses_ES
dc.typeinfo:eu-repo/semantics/conferenceObjectes_ES
dc.centroFacultad de Cienciases_ES
dc.relation.eventtitle9th International Conference on Bacillus anthracis, cereus and thuringiensises_ES
dc.relation.eventplaceFranciaes_ES
dc.relation.eventdateAbril, 2021es_ES


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