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dc.contributor.advisorMolina Fernández, Íñigo
dc.contributor.advisorHalir, Robert
dc.contributor.authorLeuermann, Jonas
dc.contributor.otherIngeniería de Comunicacioneses_ES
dc.date.accessioned2021-06-16T11:02:48Z
dc.date.available2021-06-16T11:02:48Z
dc.date.created2021-04-16
dc.date.issued2021-06-16
dc.date.submitted2021-05-07
dc.identifier.urihttps://hdl.handle.net/10630/22473
dc.descriptionOne important aspect is its immunity to laser phase noise and relative intensity noise. That means that inexpensive fixed wavelength Fabry-Perot lasers can be used with this type of sensor. This reduces the cost of the light source tremendously. Within this work it was demonstrated that it can reach cutting-edge state-of-the-art detection limits in typical bulk sensing and biosensing (with C-reactive protein) performance verification. Finally, targeting a real application scenario, the specific detection of IgG and IgE amoxicillin antibodies was demonstrated applying amoxicillin haptenised PAMAM G2 dendrimers on the sensing area.es_ES
dc.description.abstractIntegrated photonic biosensors are a highly promising technology platform for biochemical diagnostics. In general, they have demonstrated impressively low detection limits and can offer highly multiplexed operations in real time. Ring-resonator-based photonic biosensors have been shown to be a practical solution for lab-on-chip solutions and first commercial products are already available. However, they mostly require an expensive high-quality laser for accurate operation. In recent years, interferometer-based photonic sensors have demonstrated even lower detection limits as well as multiplexation capabilities and are candidates for future point-of-care devices for primary care, directly at the patient site. Point-of-care solutions require a portable and inexpensive device. The read-out, i.e. optical source, detection scheme, and signal processing, typically make up a significant part of an integrated photonic biosensor system’s price. Ring-resonator-based systems often need a tunable narrow-linewidth laser as optical source to extract the resonance wavelength, whereas interferometers just need a fixed wavelength source to accurately extract the phase shift, but can suffer from sensitivity fading and ambiguity. In this thesis we investigate a coherently read symmetric Mach-Zehnder interferometer that overcomes these drawbacks and show that it is an attractive solution for point-of-care devices for several reasons.es_ES
dc.language.isoenges_ES
dc.publisherUMA Editoriales_ES
dc.rightsinfo:eu-repo/semantics/openAccesses_ES
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.subjectInterferómetros laseres_ES
dc.subject.otherSilicon Photonicses_ES
dc.subject.otherBiosensores_ES
dc.subject.otherPoint-of-Carees_ES
dc.subject.otherAllergy Detectiones_ES
dc.titleSilicon Photonics Mach-Zehnder Biosensor with Coherent Detection for Point-of-Care Deviceses_ES
dc.typeinfo:eu-repo/semantics/doctoralThesises_ES
dc.centroE.T.S.I. Telecomunicaciónes_ES
dc.rights.ccAttribution-NonCommercial-NoDerivatives 4.0 Internacional*


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