Biología Celular, Genética y Fisiología - (BCGF)
Estas son las colecciones en las que puede catalogar la producción investigadora del departamento Biología Celular, Genética y Fisiología. Si considera que ninguna de estas se ajusta a su material pida una nueva colección en la sección de sugerencias.
Colecciones en esta comunidad
Envíos recientes
-
Impact of white adipose tissue in AD pathology
(2021-11-04)Introduction: Alzheimer’s disease (AD) is a complex disorder and multiple cellular and molecular mechanisms are involved in AD onset and progression. Recent evidences has suggested that metabolic alterations are an important ... -
Comparing astroglial reactivity in two transgenic mouse models of tauopathy
(2021-11-03)Astrocytes are becoming crucial players in the pathology of neurodegenerative disorders, such as Alzheimer’s disease (AD). Astrocyte responses have been mainly analyzed in the context of amyloid-beta (Abeta) pathology, ... -
Role of dopamine D4 receptor in the development of morphine-induced analgesic tolerance
(2021)Morphine is one of the most effective analgesic used in the clinical management of pain. However, long-term use of morphine can cause many side effects including respiratory depression, constipation, analgesic tolerance, ... -
Dopamine D4R restores morphine-induced impairment of adult neurogenesis in the subventricular zone
(2021)In the adult mammalian brain, neuroblasts from the subventricular zone (SVZ) migrate along the rostral migratory stream into the olfactory bulb, where they differentiate and synaptically integrate to contribute with the ... -
Neuraminidase-induced neuroinflammation causes anxiety and microgliosis in the amygdala
(2021)An intracerebroventricular (ICV) injection of neuraminidase (NA) within the lateral ventricles originates an acute event of neuroinflammation, which is solved to a great extent after two weeks. Recently, neurological ... -
Osmorregulación en peces. Cultivo de especies de interés comercial en diferentes salinidades ambientales
(2021-10-25)I Osmorregulación en peces Los peces son animales osmorreguladores, es decir, mantienen su osmolaridad corporal regulada y diferenciada de la del medio acuático que habitan. Las estrategias osmorreguladoras van a ser ... -
Identificación y caracterización de levaduras vínicas, un mundo por descubrir
(2021)La elaboración de vinos finos consta de dos fases fundamentales, la fermentación y la maduración biológica. Durante la fase de fermentación, Sacharomyces cerevisiae es el principal responsable de la transformación del ... -
Detection of novel antimicrobial resistance genes in oil contaminated soils by metagenomic functional analysis
(2021-10-18)Our ability to cure infections that were once considered benign or of low risk is at stake due to the development and spread of antimicrobial resistance mechanisms (AMR). One of the measures proposed to fight this problem ... -
Characterization of an ibuprofen-eater bacteria
(2021-10-13)The presence of pharmaceutical compounds (PhCs) in drinking water, treated wastewater, groundwater, surface water, and soil around the world is an emerging challenge. The bioremediation of organic pollutants by microbial ... -
Type III secretion system effectors and host specificity in Pseudomonas savastanoi pathovars of woody hosts
(2021-09)The species Pseudomonas savastanoi, a member of the Pseudomonas syringae complex, includes five pathovars causing knots or excrescences in woody hosts: P. savastanoi pv. savastanoi, pv. fraxini, pv. nerii, pv. retacarpa ... -
Fast and efficient generation of oligodendrocytes from human induced pluripotent stem cells (hiPSCs)
(Wiley, 2021-07)Oligodendrocytes (OLs) are highly specialized cells of the central nervous system responsible for myelin production and metabolic support of neurons. Defects in OLs are crucial in several neurodegenerative diseases including ... -
Caracterización del sistema de dos componentes GacS/GacA en Pseudomonas savastanoi pv. savastanoi
(Sociedad Española de Microbiología, 2021)El sistema de dos componentes GacS/GacA es considerado uno de los principales mecanismos de regulación global en bacterias. Mayoritariamente, los trabajos de caracterización del sistema GacS/GacA se han centrado en bacterias ... -
Microglial and neurogenic alterations in hypothalamus due to acute stress
(2021-07)Microglial cells are an important glial population known to be involved in several biological processes such as stress response. These cells engage an activated state following a stress insult that may lead to nervous ... -
Anxiety and mild microglial activation in the amygdala two weeks after NA-induced neuroinflammation
(Wiley Periodicals, LLC, 2021-07)A single injection of neuraminidase (NA) within the cerebral ventricles (ICV) triggers an acute neuroinflammation. Neurological complications or behavioral alterations have been associated to neuroinflammation. While some ... -
Coexistance of different damage-associated myeloid populations in the hippocampus of Alzheimer's patients
(Wiley, 2021)Parenchymal microglia are the brain-resident immune cells capable of responding to damage. Though the role of microglial cells in the development/progression of AD is still unknown, a dysfunctional response has recently ... -
La rizobacteria Pseudomonas alcaligenes AVO110 induce la expresión de genes relacionados con formación de biofilms en respuesta a exudados de Rosellinia necatrix
(2021-06)La rizobacteria Pseudomonas alcaligenes AVO110 muestra antagonismo frente al hongo fitopatógeno Rosellinia necatrix. Esta cepa coloniza eficazmente las hifas de R. necatrix y es capaz de alimentarse de sus exudados. ... -
The bacterial effector HopZ1a acetylates MKK7 to suppress plant immunity
(Wiley, 2021)The Pseudomonas syringae type III secretion system translocates effector proteins into the host cell cytosol to suppress plant basal immunity. Effector HopZ1a suppresses local and sys- temic immunity triggered by ... -
Suitability of human-derived cells as a platform for Alzheimer's disease modeling
(2021)Aims: Alzheimer's disease (AD) is characterized by presenting a complex pathology, not fully resolved yet. This fact, together with the lack of reliable models, has impeded the development of effective therapies. Recently, ... -
18F-THK5351 PET imaging, neuropathology and clinical progression in a tau mouse model
(Alzheimer disease & Parkinson disease Conference 2021, 2021)Aims: Alzheimer’s disease (AD) and other associated dementias remain a consistent and unruly problem for the aging population and health. The neuropathology of AD is characterized by the extracellular deposition of ... -
Microtubule stabilization reduces amyloid pathology and improves synaptic/memory deficits in APP/PS1 mice
(Alzheimer disease & Parkinson disease Conference 2021, 2021)Aims: Cognitive decline in Alzheimer's disease (AD) is highly related to synaptic/neuronal loss. Tau hyperphosphorylation destabilizes microtubules leading to axonal transport failure and generation of dystrophic neurites, ...