Biología Celular, Genética y Fisiología - (BCGF)
Estas son las colecciones en las que puede catalogar la producción investigadora del departamento Biología Celular, Genética y Fisiología. Si considera que ninguna de estas se ajusta a su material pida una nueva colección en la sección de sugerencias.
Colecciones en esta comunidad
Envíos recientes
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Desarrollo de prototipos de soportes tridimensionales a base de colágeno tipo I e hidroxiapatita para regeneración ósea
(UMA Editorial, 2022)El hueso es uno de los tejidos de mayor demanda para trasplante a nivel mundial, representando cerca de 2,2 millones de injertos anualmente. Por medio de la ingeniería de tejidos ósea (BTE) se han desarrollado estrategias ... -
Deciphering the role of vesicle trafficking in geminiviral infection
(UMA Editorial, 2022)Esta tesis está dividida en dos partes claramente diferenciadas. En la primera parte se ha investigado el papel que juega el tráfico vesicular en las infecciones causadas por geminivirus, mientras que la segunda se ... -
Sudden cessation of fluoxetine before alcohol drinking reinstatement alters microglial morphology and TLR4/inflammatory neuroadaptation in the rat brain
(SPRINGER, 2021-07-08)Preclinical studies on the efects of abrupt cessation of selective serotonin reuptake inhibitors (SSRIs), a medication often prescribed in alcohol use disorder (AUD) patients with depression, results in alcohol consumption ... -
Impact of white adipose tissue in AD pathology
(2022)Aims: Alzheimer’s disease (AD) is a complex disorder and multiple cellular and molecular mechanisms are involved in AD onset and progression. Recent evidences has suggested that metabolic alterations are an important ... -
Human amyloid seeds aggregate more efficient than seeds from old 3xtg-ad mice
(2022)Aims: Most age-associated neurodegenerative disorders involve the aggregation of specific proteins within the nervous system, as occurs in Alzheimer’s disease (AD). Recent evidence indicates that Aβ can misfold and aggregate ... -
Human pluripotent stem cell-derived astrocytes from alzheimer´s disease patients for disease modeling
(2022)Aims: The lack of reliable models of Alzheimer´s disease (AD) has impeded the development of effective therapies. Glial cells have a key role in AD pathology, but this cannot be properly modeled using available animal ... -
Tau pathology and astroglial reactivity: a comparative study of two mouse models of tauopathy
(2022)Objectives: Astrocytes are becoming crucial players in the context of neurodegenerative proteinopathies, such as Alzheimer’s disease (AD). Astroglial response has been mainly analyzed in amyloidogenic scenarios, but less ... -
Diversity of plaque-associated myeloid cells subtypes in human alzheimer’s disease brain
(2022)Aims: Parenchymal microglia, as well other myeloid cells, have been postulated as a critical factor in Alzheimer´s disease (AD) pathogenesis since the identification of genetic risk factors related to their functions. ... -
Paisaje molecular del tratamiento neoadyuvante en cáncer de mama: predicción de la respuesta, resistencia y recaída a distancia
(UMA Editorial, 2021-12-16)El tratamiento citotóxico Neoadyuvante en el cáncer de mama, basado en la administración de Antraciclinas +/- Taxanos (más Trastuzumab en aquellos casos con sobreexpresión de HER2) antes de la cirugía en pacientes con ... -
Amyloid propagation in a sporadic model of Alzheimer disease
(2021-11-04)Most age-associated neurodegenerative disorders involve the aggregation of specific proteins within the nervous system, as occurs in Alzheimer’s disease (AD). Recent evidence indicates that Aβ can misfold and aggregate ... -
Impact of white adipose tissue in AD pathology
(2021-11-04)Introduction: Alzheimer’s disease (AD) is a complex disorder and multiple cellular and molecular mechanisms are involved in AD onset and progression. Recent evidences has suggested that metabolic alterations are an important ... -
Comparing astroglial reactivity in two transgenic mouse models of tauopathy
(2021-11-03)Astrocytes are becoming crucial players in the pathology of neurodegenerative disorders, such as Alzheimer’s disease (AD). Astrocyte responses have been mainly analyzed in the context of amyloid-beta (Abeta) pathology, ... -
Role of dopamine D4 receptor in the development of morphine-induced analgesic tolerance
(2021)Morphine is one of the most effective analgesic used in the clinical management of pain. However, long-term use of morphine can cause many side effects including respiratory depression, constipation, analgesic tolerance, ... -
Dopamine D4R restores morphine-induced impairment of adult neurogenesis in the subventricular zone
(2021)In the adult mammalian brain, neuroblasts from the subventricular zone (SVZ) migrate along the rostral migratory stream into the olfactory bulb, where they differentiate and synaptically integrate to contribute with the ... -
Neuraminidase-induced neuroinflammation causes anxiety and microgliosis in the amygdala
(2021)An intracerebroventricular (ICV) injection of neuraminidase (NA) within the lateral ventricles originates an acute event of neuroinflammation, which is solved to a great extent after two weeks. Recently, neurological ... -
Osmorregulación en peces. Cultivo de especies de interés comercial en diferentes salinidades ambientales
(2021-10-25)I Osmorregulación en peces Los peces son animales osmorreguladores, es decir, mantienen su osmolaridad corporal regulada y diferenciada de la del medio acuático que habitan. Las estrategias osmorreguladoras van a ser ... -
Identificación y caracterización de levaduras vínicas, un mundo por descubrir
(2021)La elaboración de vinos finos consta de dos fases fundamentales, la fermentación y la maduración biológica. Durante la fase de fermentación, Sacharomyces cerevisiae es el principal responsable de la transformación del ... -
Detection of novel antimicrobial resistance genes in oil contaminated soils by metagenomic functional analysis
(2021-10-18)Our ability to cure infections that were once considered benign or of low risk is at stake due to the development and spread of antimicrobial resistance mechanisms (AMR). One of the measures proposed to fight this problem ... -
Characterization of an ibuprofen-eater bacteria
(2021-10-13)The presence of pharmaceutical compounds (PhCs) in drinking water, treated wastewater, groundwater, surface water, and soil around the world is an emerging challenge. The bioremediation of organic pollutants by microbial ... -
Type III secretion system effectors and host specificity in Pseudomonas savastanoi pathovars of woody hosts
(2021-09)The species Pseudomonas savastanoi, a member of the Pseudomonas syringae complex, includes five pathovars causing knots or excrescences in woody hosts: P. savastanoi pv. savastanoi, pv. fraxini, pv. nerii, pv. retacarpa ...