Listar Biología Celular, Genética y Fisiología - (BCGF) por título
Mostrando ítems 104-123 de 423
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D-chiro-inositol prevents memory deficits in the 3xTg mouse model of Alzheimer’s disease in a sex-dependent manner.
(2023)Alzheimer’s disease (AD) is recognized as an age-related neurodegenerative disorder, characterized by the aggregation and deposition of amyloid-β (Aβ) in plaques and neurofibrillary tangles (NFTs) composed of aggregates ... -
De la vida libre al biofilm y vuelta atrás
(2016-12-02)La alternancia entre un estilo de vida libre planctónico y la formación de comunidades estructuradas, altamente cooperativas y embebidas en una matriz polimérica, denominadas biofilms, es una característica central de la ... -
Deciphering the role of vesicle trafficking in geminiviral infection
(UMA Editorial, 2022)Esta tesis está dividida en dos partes claramente diferenciadas. En la primera parte se ha investigado el papel que juega el tráfico vesicular en las infecciones causadas por geminivirus, mientras que la segunda se ... -
Decoding damage-associated microglia in post mortem hippocampus of Alzheimer’s disease patients
(2019-07-18)The relationship between Alzheimer’s disease (AD) and neuroinflammation has become stronger since the identification of several genetic risk factors related to microglial function. Though the role of microglial cells in ... -
Dendritic scaffold onto titanium implants. A versatile strategy increasing biocompatibility.
(MDPI, 2020-04-01)Osseointegration of metal prosthetic implants is a yet unresolved clinical need that depends on the interplay between the implant surface and bone cells. The lack of a relationship between bone cells and metal has traditionally ... -
Desarrollo de implantes protesicos personalizados mediante impresión 3D de metales para el tratamiento quirúrgico de defectos maxilares
(2022)La osteonecrosis mandibular es una patología que suele presentarse como efecto secundario de la radioterapia con que se tratan los procesos oncológicos de cabeza y cuello, o después de tratamientos prolongados con bifosfonatos. ... -
Desarrollo de prototipos de soportes tridimensionales a base de colágeno tipo I e hidroxiapatita para regeneración ósea
(UMA Editorial, 2022)El hueso es uno de los tejidos de mayor demanda para trasplante a nivel mundial, representando cerca de 2,2 millones de injertos anualmente. Por medio de la ingeniería de tejidos ósea (BTE) se han desarrollado estrategias ... -
Desarrollo del epéndimo y subepéndimo en modelos animales en condiciones normales y en la hidrocefalia congénita
(Servicio de Publicaciones y Divulgacion Cientifica, 2016)La presente Tesis Doctoral se ha diseñado para responder a las siguientes hipótesis: 1.- El programa de diferenciación de la zona ventricular que se afecta en el ratón hyh pone de manifiesto que la población celular que ... -
Detección y caracterización de virus emergentes de ADN de plantas para una agricultura sostenible
(2017-11-06)Los virus de la familia Geminiviridae son virus de ADN monocatenario circular mono- o bipartito encapsulados en partículas geminadas que afectan a cultivos de plantas mono y dicotiledóneas. Los geminivirus son patógenos ... -
Detection of novel antimicrobial resistance genes in oil contaminated soils by metagenomic functional analysis
(2019-10-02)Background Our ability to cure infections that were once considered benign or of low risk is at stake due to the development and spread of antimicrobial resistance mechanisms (AMR). One of the measures proposed to fight ... -
Development of in vitro systems to study IFN signalling in gilthead seabream (Sparus aurata)
(2014-12-11)Type I interferon (IFN I) triggers specific signalling pathways leading to the activation of the innate immune defence of vertebrates against viral infections. In contrats, type II IFN (IFN II) is generally accepted to be ... -
Diagnosis of immediate reactions to amoxicillin: Comparison of basophil activation markers CD63 and CD203c in a prospective study
(Wiley, 2022-12-07)Amoxicillin (AX) combined or not with clavulanic acid (CLV) is frequently involved in IgE-mediated reactions. Drug provocation test (DPT) is considered as the gold standard for diagnosis, although contraindicated in high-risk ... -
Dietary administration of D-chiro-inositol attenuates sex-specific metabolic imbalances in the 5xFAD mouse model of Alzheimer’s disease
(Elsevier, 2022-06)Increasing evidence shows that hypothalamic dysfunction, insulin resistance, and weight loss precede and progress along with the cognitive decline in sporadic Alzheimer’s Disease (AD) with sex differences. This study aimed ... -
Differential induction of the gilthead seabream Mx1, Mx2 and Mx3 promoters by IPNV and VHSV
(2014-10-07)Type I interferon (IFN I) system triggers specific signalling pathways leading to the activation of the innate immune defence of vertebrates against viral infections. The complex expression regulation of Interferon Stimulated ... -
Discerning the relationship between geminiviral infection and vesicle trafficking using virus induced gene silencing
(2017-06-26)Tomato yellow leaf curl disease is one of the most important threats to tomato crops worldwide. One of its causal agents, Tomato yellow leaf curl Sardinian virus (TYLCSV) is a monopartite member of the genus Begomovirus ... -
Diseño de nuevas estrategias moleculares para la funcionalización de colágeno tipo I en ingeniería tisular ósea
(UMA Editorial, 2018)El colágeno tipo I, funcionalizado con proteína morfogenética de hueso 2 (BMP-2), es un biomaterial ampliamente utilizado en ingeniería tisular y cirugía ortopédica como alternativa al implante de hueso autólogo en los ... -
Disentangling the contribution of tau and abeta pathologies in transgenic models of Alzheimer's disease
(2018-07-20)AIMS: Amyloid-beta (Abeta) deposits and intraneuronal hyperphosphorylated tau are major pathological hallmarks of Alzheimer’s disease (AD). The coexistence of these aggregates in AD brains leads to synaptic dysfunction, ... -
Dissecting the microglial response in transgenic models of amyloidogenesis and tauopathy
(2019-07-19)Amyloid-beta (Abeta) peptide deposits and hyperphosphorylated tau protein (phospho-tau) accumulate in Alzheimer’s disease (AD) brains. These abnormal protein aggregates leads to glial activation, synaptic dysfunction, ... -
Dissecting the relevance of vesicle trafficking for the movement of geminiviruses
(2022-09)Tomato yellow leaf curl disease is one of the most important threats to tomato crops worldwide. One of its causal agents, Tomato yellow leaf curl Sardinian virus (TYLCSV), is a monopartite member of the genus Begomovirus ... -
Distinct disease-sensitive GABAergic neurons in the perirhinal cortex of Alzheimer's mice and patients
(Wiley, 2020-03)Neuronal loss is the best neuropathological substrate that correlates with cortical atrophy and dementia in Alzheimer's disease (AD). Defective GABAergic neuronal functions may lead to cortical network hyperactivity and ...