Listar Biología Celular, Genética y Fisiología - (BCGF) por título
Mostrando ítems 184-203 de 423
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Galectin-3, a novel endogenous TREM2 ligand, detrimentally regulates inflammatory response in Alzheimer's disease.
(Springer, 2019-04-20)Alzheimer's disease (AD) is a progressive neurodegenerative disease in which the formation of extracellular aggregates of amyloid beta (Aβ) peptide, fibrillary tangles of intraneuronal tau and microglial activation are ... -
Geminiviral protein Rep interferes in PCNA sumoylation
(2015-10-21)Rep is a multifunctional protein essential for replication of geminivirus that interferes with the sumoylation of a key protein in the DNA replication, PCNA (Proliferating Cell Nuclear Antigen). It is known that Rep is ... -
Geminivirus Rep Protein Interferes with the Plant DNA Methylation Machinery and Modifies the Host Epigenome
(2016-09-27)The apparent simplicity of viruses hides the complexity of their interactions with their hosts. Viruses are masters at circumventing host defenses and manipulating the cellular environment for their own benefit. The ... -
Geminivirus Rep Protein Interferes with the Plant DNA Methylation Machinery and Suppresses Transcriptional Gene Silencing
(2013-12-13)Cytosine methylation is an epigenetic mark that promotes gene silencing and plays an important role in genome defense against transposons and invading DNA viruses. So far just one geminiviral protein, C2 from Tomato golden ... -
Geminivirus Rep Protein Interferes with the Plant DNA Methylation Machinery and Suppresses Transcriptional Gene Silencing
(2015-07-06)The apparent simplicity of viruses hides the complexity of their interactions with their hosts. Viruses are masters at circumventing host defenses and manipulating the cellular environment for their own benefit. The ... -
Geminivirus Rep Protein Interferes with the Plant DNA Methylation Machinery and Suppresses Transcriptional Gene Silencing
(2015-10-20)Viruses are masters at circumventing host defenses and manipulating the cellular environment for their own benefit. The replication of the largest known family of single-stranded DNA viruses, Geminiviridae, is impaired by ... -
Geminivirus replication protein decreases PCNA sumoylation at two acceptor sites
(2019-06-07)Geminiviruses are plant viruses with circular, single-stranded DNA (ssDNA) genomes that infect a broad range of plants causing substantial crop diseases worldwide. They replicate in nuclei of infected cells by using host ... -
Geminivirus replication protein impairs sumo conjugation of PCNA at two acceptor sites
(2018-07-12)Geminiviruses are plant viruses with circular, single-stranded DNA (ssDNA) genomes that infect a broad range of plants causing substantial crop diseases worldwide. They replicate in nuclei of infected cells by using host ... -
Geminivirus replication protein impairs sumo conjugation of PCNA at two acceptor sites
(2018-10-29)Geminiviruses are plant viruses with circular, single-stranded DNA (ssDNA) genomes that infect a broad range of plants causing substantial crop diseases worldwide. They replicate in nuclei of infected cells by using host ... -
Geminivirus Replication Protein impairs SUMO conjugation of PCNA at two acceptor sites.
(ASM Journals, 2018-06-27)Geminiviruses are DNA viruses that replicate in nuclei of infected plant cells using the plant DNA replication machinery, including PCNA (proliferating cellular nuclear antigen), a cofactor that orchestrates genome duplication ... -
Geminiviruses for biotechnology: the art of parasite taming
(2017-11-16)Viruses are intracellular pathogens that have evolved efficient strategies for replication and expression of their proteins in the host cells. Geminiviruses – plant viruses with small circular single-stranded DNA genomes ... -
Geminiviruses: molecular and genetic characterization of their interaction with the plant.
(UMA Editorial, 2024)Esta tesis se centra en el estudio de la interacción de los geminivirus con su hospedador. Los geminivirus son una familia de pequeños virus no envueltos con genomas que comprenden uno o dos ADN circulares de cadena sencilla ... -
El gen iaaL en el complejo Pseudomonas syringae: caracterización funcional y actividad biológica
(2022)Las bacterias fitopatógenas del complejo Pseudomonas syringae son agentes causales de enfermedades en multitud de huéspedes leñosos y herbáceos. El ácido indol-3-acético (IAA) es una fitohormona tipo auxina cuya producción ... -
Generation and characterization of human ipscderived neural precursors and astrocytes to model Alzeimer’s disease
(2022)Background: Alzheimer's disease (AD) is characterized by presenting a complex pathology, not fully resolved yet. This fact, together with the lack of reliable models, has impeded the development of effective therapies. ... -
Generation of periventricular reactive astrocytes overexpressing aquaporin 4 Is stimulated by mesenchymal stem cell therapy
(MDPI, 2023-03-15)Aquaporin-4 (AQP4) plays a crucial role in brain water circulation and is considered a therapeutic target in hydrocephalus. Congenital hydrocephalus is associated with a reaction of astrocytes in the periventricular white ... -
Genetic and epigenetic characterization of the geminivirus-host interaction
(UMA Editorial, 2019-11)Los geminivirus constituyen una familia de virus de plantas transmitidos por insectos, contienen una o dos moléculas de DNA de cadena sencilla empaquetadas en dos partículas gemelas fusionadas. Es uno de los patógenos de ... -
The genomic history of the Iberian peninsula over the past 8000 years.
(2019)The lberian Península provides an excellent context in which to assess the final impact of population movements entering the European continent from the east as well as prehistoric and historie connections with North ... -
Gilthead seabream (Sparus aurata) Mx proteins show positive and negative synergy in their antiviral activity
(2014-10-07)Due to their direct antiviral activity, Mx proteins play a main role in the response mediated by the type I interferon against viral infections. The study of the farmed fish gilthead seabream Mx genes is specially interesting, ... -
Glia and neurons from human iPSCs to address the pathology of Alzheimer´s disease
(2023)Alzheimer's disease (AD) is characterized by presenting a complex pathology, not fully resolved yet. This fact, together with the lack of reliable models, has impeded the development of effective therapies. Recently, ... -
Glicoproteínas como dianas para el diseño de antifúngicos
(2018-11-20)Glicoproteínas como dianas para el diseño de antifúngicos Las infecciones por hongos patógenos causan grandes pérdidas en la agricultura y economía a nivel mundial. Aunque desde hace décadas se están estudiando los ...