Listar BCGF - Artículos por título
Mostrando ítems 58-77 de 187
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Early development of anti-natalizumab antibodies in MS patients
Oliver-Martos, Begoña
; Órpez, Teresa; Urbaneja, Patricia; Maldonado-Sanchez, Rafael; Leyva-Fernández, Laura; Fernández Fernández, Óscar[et al.] (SpringerLink, 2013)
The purpose of this study is to monitor the development of anti-natalizumab antibodies to evaluate their first appearance in multiple sclerosis patients, since their presence has been associated with a reduction in the ... -
Early neuronal loss and axonal/presynaptic damage is associated with accelerated amyloid-β accumulation in AβPP/PS1 Alzheimer's disease mice subiculum.
Trujillo-Estrada, Laura Isabel; Dávila-Cansino, José Carlos; Sánchez-Mejías, Elisabeth; Sánchez-Varo, Raquel María; Gómez-Arboledas, Ángela; Vizuete, Marisa; Vitorica, Javier; Gutiérrez-Pérez, Antonia[et al.] (IOS Press, 2014)
The progressive cognitive decline leading to dementia in Alzheimer’s disease (AD) patients is the consequence of a severe loss of synapses and neurons affecting particular cell subpopulations in selected brain areas, with ... -
Effect of acute and chronic red wine consumption on lipopolysaccharide concentrations
Clemente-Postigo, María Mercedes; Queipo-Ortuño, María Isabel; Boto-Ordóñez, María; Coín-Aragüez, Leticia I.; Roca-Rodríguez, María del Mar; Delgado-Lista, J.; Cardona-Díaz, Fernando; Andrés-Lacueva, Cristina; Tinahones-Madueño, Francisco José[et al.] (Elsevier (The American Journal of Clinical Nutrition), 2013)
Background: Chronic red wine (RW) consumption has been associated with decreased cardiovascular disease risk, mainly attributed to an improvement in lipid profile. RW intake is also able to change the composition of gut ... -
Effect of apolipoprotein C3 and apolipoprotein A1 polymorphisms on postprandial response to a fat overload in metabolic syndrome patients
Clemente-Postigo, María Mercedes; Queipo-Ortuño, María Isabel; Valdivieso-Felices, Pedro; Tinahones-Madueño, Francisco José; Cardona-Díaz, Fernando (Elsevier. The Canadian Society of Clinical Chemists., 2010)
Objectives: Apolipoprotein C-III (APOC3) is a component of triglyceride rich lipoproteins, and SstI polymorphism has been associated with hypertriglyceridemia. Apolipoprotein A-I (APOA1) is the major component of HDL and ... -
Effects of glucagon-like peptide-1 on the differentiation and metabolism of human adipocytes.
El-Bekay, Rajaa; Coín-Aragüez, Leticia I.; Fernandez-García, Diego; Oliva Olivera, Wilfredo; Bernal-López, María Rosa; Clemente-Postigo, María Mercedes; Delgado-Lista, Javier; Díaz-Ruiz, Alberto; Guzmán-Ruiz, Rocio; Vázquez-Martínez, Rafael; Lhamyani, Said; Roca-Rodríguez, María del Mar; Fernández-Veledo, Sonia; Vendrell, Joan; Malagón, Maria M.; Tinahones-Madueño, Francisco José[et al.] (British Pharmacological Society, 2016-03-18)
Glucagon-like peptide-1 (GLP-1) analogues improve glycaemic control in type 2 diabetic (T2D) patients and cause weight loss in obese subjects by as yet unknown mechanisms. We recently demonstrated that the GLP-1 receptor, ... -
Endotoxin increase after fat overload is related to postprandial hypertriglyceridemia in morbidly obese patients
Clemente-Postigo, María Mercedes; Queipo-Ortuño, María Isabel; Murri, Mora; Boto-Ordóñez, María; Pérez-Martínez, Pablo; Andrés-Lacueva, Cristina; Cardona-Díaz, Fernando; Tinahones-Madueño, Francisco José[et al.] (American Society for Biochemistry and Molecular Biology, 2012)
The low-grade inflammation observed in obesity has been associated with a high-fat diet, though this relation is not fully understood. Bacterial endotoxin, produced by gut microbiota, may be the linking factor. However, ... -
Enhancing arbuscular mycorrhiza symbiosis effectiveness through the involvement of the tomato GRAS transcription factor SCL3/SlGRAS18
Avilés-Cárdenas, Jonathan; Molinero-Rosales, Nuria; Pérez-Tienda, Jacob; Rosas-Díaz, Tábata Victoria; Castillo-Garriga, Araceli; García-Garrido, José M.[et al.] (Elsevier, 2024-08)
Arbuscular mycorrhizal (AM) fungi improve plant growth, nutrition, fitness and stress tolerance while AM fungi obtain carbohydrates and lipids from the host. This whole process of mutual benefit requires substantial ... -
Enhancing microtubule stabilization rescues cognitive deficits and ameliorates pathological phenotype in an amyloidogenic Alzheimer's disease model.
Fernández-Valenzuela, Juan José; Sánchez-Varo, Raquel María; Muñoz-Castro, Clara; De Castro Carratalá, Vanessa; Sánchez-Mejías, Elisabeth; Navarro, Victoria; Jimenez, Sebastian; Núñez-Díaz, Cristina; Gómez-Arboledas, Ángela; Moreno-González, Inés; Vizuete, Marisa; Dávila-Cansino, José Carlos; Vitorica, Javier; Gutiérrez-Pérez, Antonia[et al.] (Springer Nature, 2020-09-08)
In Alzheimer's disease (AD), and other tauopathies, microtubule destabilization compromises axonal and synaptic integrity contributing to neurodegeneration. These diseases are characterized by the intracellular accumulation ... -
ER Bodies Are Induced by Pseudomonas syringae and Negatively Regulate Immunity.
Rufián Plaza, José Sebastián; Elmore, James M.; Rodríguez-Bejarano, Eduardo; Beuzón-López, Carmen del Rosario; Coaker, Gitta L. (APS, 2021-09-29)
ER bodies are endoplasmic reticulum–derived organelles present in plants belonging to the Brassicales order. In Arabidopsis thaliana, ER bodies are ubiquitous in cotyledons and roots and are present only in certain cell ... -
Exploratory, anxiety and spatial memory impairments are dissociated in mice lacking the LPA1 receptor
Castilla-Ortega, María Estela; Sánchez-López, Jorge; Hoyo-Becerra, Carolina; Matas-Rico, Elisa; Zambrana-Infantes, Emma; Chun, Jerold; Rodríguez de Fonseca, Fernando; Pedraza-Benítez, María del Carmen; Estivill-Torrús, Guillermo; Santín-Núñez, Luis Javier[et al.] (Elsevier, 2010-07)
Lysophosphatidic acid (LPA) is a new, intercellular signalling molecule in the brain that has an important role in adult hippocampal plasticity. Mice lacking the LPA1 receptor exhibit motor, emotional and cognitive ... -
Expression of Gls and Gls2 glutaminase isoforms in astrocytes
Cardona, Carolina; Sánchez-Mejías, Elisabeth; Dávila-Cansino, José Carlos; Martín-Rufián, Mercedes; Campos-Sandoval, José Ángel; Vitorica, Javier; Alonso-Carrión, Francisco José; Mates-Sánchez, José Manuel; Segura-Checa, Juan Antonio; Norenberg, Michael D.; Rama Rao, Kakulavarapu V.; Jayakumar, Arumugan R.; Gutiérrez-Pérez, Antonia; Márquez-Gómez, Javier[et al.] (Wiley, 2015-03)
The expression of glutaminase in glial cells has been a controversial issue and matter of debate for many years. Actually, glu-taminase is essentially considered as a neuronal marker in brain. Astrocytes are endowed with ... -
FABP4 Dynamics in Obesity: Discrepancies in Adipose Tissue and Liver Expression Regarding Circulating Plasma Levels
Queipo-Ortuño, María Isabel; Escoté Miró, Xavier; Ceperuelo-Mallafré, Victoria; Garrido-Sánchez, Lourdes; Miranda, Merce; Clemente-Postigo, María Mercedes; Pérez-Pérez, Rafael; Peral Fuentes, Belén; Cardona-Díaz, Fernando; Fernández Real, José M; Tinahones-Madueño, Francisco José; Vendrell Ortega, Joan[et al.] (PLOS (Public Library of Science), 2012)
Background FABP4 is predominantly expressed in adipose tissue, and its circulating levels are linked with obesity and a poor atherogenic profile. Objective In patients with a wide BMI range, we analyze FABP4 expression ... -
Functional Analysis of Gene-Silencing Suppressors from Tomato Yellow Leaf Curl Disease Viruses
Pérez-Luna, Ana Isabel; Morilla, Gabriel; Voinnet, Olivier; Rodríguez-Bejarano, Eduardo (APS Publications, 2012-06-01)
Tomato yellow leaf curl disease (TYLCD) is caused by a complex of phylogenetically related Begomovirus spp. that produce similar symptoms when they infect tomato plants but have different host ranges. In this work, we ... -
Functional Analysis of V2 Protein of Beet Curly Top Iran Virus
Bahari, Atiyeh; Castillo-Garriga, Araceli; Safaie, Naser; Bejarano, Eduardo R.; Pérez-Luna, Ana Isabel; Shams-Bakhsh, Masoud[et al.] (IOAP-MDPI, 2022-12-02)
El virus Geminivirus de la punta rizada de la remolacha de Irán (BCTIV) es uno de los principales agentes causales de la enfermedad de la punta rizada de la remolacha en Irán y la especie tipo del género Becurtovirus ... -
GABAergic deficits in absence of LPA1 receptor, associated anxiety-like and coping behaviors, and amelioration by interneuron precursor transplants into the dorsal hippocampus
Rosell-Valle, Cristina; Martínez-Losa, Magdalena; Matas-Rico, Elisa; Castilla-Ortega, María Estela; Zambrana-Infantes, Emma; Gómez-Conde, Ana Isabel; Sánchez-Salido, Lourdes; Ladrón de Guevara-Miranda, David; Pedraza-Benítez, María del Carmen; Serrano-Castro, Pedro Jesús; Chun, Jerold; Rodríguez de Fonseca, Fernando; Álvarez Dolado, Manuel; Santín-Núñez, Luis Javier; Estivill-Torrús, Guillermo[et al.] (Springer Link, 2021-04-01)
Defects in GABAergic function can cause anxiety- and depression-like behaviors among other neuropsychiatric disorders. Therapeutic strategies using the transplantation of GABAergic interneuron progenitors derived from the ... -
Galectin-3, a novel endogenous TREM2 ligand, detrimentally regulates inflammatory response in Alzheimer's disease.
Boza-Serrano, Antonio; Ruiz, Rocio; Sánchez-Varo, Raquel María; García‑Revilla, Juan; Yang, Yiyi; Jiménez-Ferrer, Itzia; Paulus, Agnes; Wennström, Malin; Vilalta, Ana; Allendorf, David; Dávila-Cansino, José Carlos; Stegmayr, John; Jiménez, Sebastián; Roca-Ceballos, Maria A.; Navarro-Garrido, Victoria; Swanberg, Maria; Hsieh, Christine L.; Real-Navarrete, Luis Miguel; Englund, Elisabeth; Linse, Sara; Leffler, Hakon; Nilsson, Ulf J.; Gutiérrez-Pérez, Antonia; Vitorica, Javier; Venero, José Luis; Deierborg, Thomas[et al.] (Springer, 2019-04-20)
Alzheimer's disease (AD) is a progressive neurodegenerative disease in which the formation of extracellular aggregates of amyloid beta (Aβ) peptide, fibrillary tangles of intraneuronal tau and microglial activation are ... -
GDE2-RECK controls ADAM10 α-secretase-mediated cleavage of amyloid precursor protein
(American Association for the Advancement of Science, 2021-03)A disintegrin and metalloprotease 10 (ADAM10) is the α-secretase for amyloid precursor protein (APP). ADAM10 cleaves APP to generate neuroprotective soluble APPα (sAPPα), which precludes the generation of Aβ, a defining ... -
Geminivirus Replication Protein impairs SUMO conjugation of PCNA at two acceptor sites.
Arroyo-Mateos, Manuel; Sabarit Penalosa, Blanca; Maio, Francesca; Sánchez-Durán, Miguel A.; Rosas-Díaz, Tábata Victoria; Prins, Marcel; Ruiz-Albert, Francisco Javier; Pérez-Luna, Ana Isabel; Van den Burg, Harrold; Rodríguez-Bejarano, Eduardo[et al.] (ASM Journals, 2018-06-27)
Geminiviruses are DNA viruses that replicate in nuclei of infected plant cells using the plant DNA replication machinery, including PCNA (proliferating cellular nuclear antigen), a cofactor that orchestrates genome duplication ...