Listar BCGF - Artículos por tipo "info:eu-repo/semantics/submittedVersion"
Mostrando ítems 1-4 de 4
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Absence of LPA1 signaling results in defective cortical development
Estivill-Torrús, Guillermo; Llebrez Zayas, Pedro; Matas-Rico, Elisa; Rodríguez de Fonseca, Fernando; Chun, Jerold; Santín-Núñez, Luis Javier
; Pedraza-Benítez, María del Carmen; De-Diego-Barbado, Isabel; Del Arco-Herrera, Ignacio; Fernández-Llebrez, Pedro[et al.] (Oxford academy, 2008-04)
Lysophosphatidic acid (LPA) is a simple phospholipid with extracellular signaling properties mediated by specific G protein-coupled receptors. At least 2 LPA receptors, LPA(1) and LPA(2), are expressed in the developing ... -
Ascorbic acid and its transporter SVCT2, affect radial glia cells differentiation in postnatal stages
Saldivia, Natalia; Salazar, Katterine; Cifuentes-Rueda, Manuel; Espinoza, F; Harrison, FE; Nualart, Francisco[et al.] (Wiley, 2024-04)
Radial glia (RG) cells generate neurons and glial cells that make up the cerebral cortex. Both in rodents and humans, these stem cells remain for a specific time after birth, named late radial glia (lRG). The knowledge of ... -
Exploratory, anxiety and spatial memory impairments are dissociated in mice lacking the LPA1 receptor
Castilla-Ortega, María Estela; Sánchez-López, Jorge; Hoyo-Becerra, Carolina; Matas-Rico, Elisa; Zambrana-Infantes, Emma; Chun, Jerold; Rodríguez de Fonseca, Fernando; Pedraza-Benítez, María del Carmen; Estivill-Torrús, Guillermo; Santín-Núñez, Luis Javier[et al.] (Elsevier, 2010-07)
Lysophosphatidic acid (LPA) is a new, intercellular signalling molecule in the brain that has an important role in adult hippocampal plasticity. Mice lacking the LPA1 receptor exhibit motor, emotional and cognitive ... -
GDE2-RECK controls ADAM10 α-secretase-mediated cleavage of amyloid precursor protein
(American Association for the Advancement of Science, 2021-03)A disintegrin and metalloprotease 10 (ADAM10) is the α-secretase for amyloid precursor protein (APP). ADAM10 cleaves APP to generate neuroprotective soluble APPα (sAPPα), which precludes the generation of Aβ, a defining ...