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Listar Biología Molecular y Bioquímica - (BMB) por autor "Claros-Díaz, Manuel Gonzalo"
Mostrando ítems 1-14 de 14
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A workflow with dedicated tools for preparing reference transcriptomes from non-model organisms has evidenced important biological information
Claros-Díaz, Manuel Gonzalo; Benzekri, Hicham; Seoane, Pedro; Carmona Muñoz, Rosario Maria; Bautista-Moreno, Rocío; Guerrero-Fernández, Darío; Fernández-Pozo, Noé[et al.] (2014-10-01)Construction transcriptomes of non-model organisms is a common task nowadays due to the advent of low-cost sequencing platforms. The non-model organisms require a de novo assembling strategy since no reference is available. ... -
Análisis Bioinformático del Transcriptoma del Pino
Fernández-Pozo, Noé (UMA Editorial, 2021-09-17)Las especies del género Pinus son de gran interés económico y ecológico en todo el mundo, y especialmente en el hemisferio norte. Sin embargo estas especies carecen de un genoma secuenciado debido a la complejidad y los ... -
Bioinformatic analyses of olive pollen tube and seed transcriptomes and their integration in an interactive olive expression atlas
Bullones, Amanda; Fernández-Pozo, Noé; Lima-Cabello, Elena; Castro, Antonio Jesús; Alché-Ramírez, Juan de Dios; Claros-Díaz, Manuel Gonzalo[et al.] (2022)The olive tree (Olea europaea L.) is of great socioeconomic importance due to the production of oil and table olives, and the seed is also an emergent source of nutraceuticals (Jiménez-Ruiz et al., 2020) and feed supplements ... -
Biomarcadores de cáncer de pulmón basados en la expresión de genes, transportes y secuencias repetitivas.
Arroyo Varela, Macarena (UMA Editorial, 2020-02-21)Uno de los grandes avances terapéuticos es la medicina personalizada, que se basa en biomarcadores que ayudan en la filiación y elección del tratamiento. La mayoría de los biomarcadores se basan en variaciones génicas y ... -
Biomarker potential of repetitive-element transcriptome in lung cancer
Claros-Díaz, Manuel Gonzalo; Arroyo, Macarena; Bautista-Moreno, Rocío; Larrosa-Jiménez, Rafael; Cobo, Manuel Ángel (PeerJ, 2019)Since repetitive elements (REs) account for nearly 53% of the human genome, profiling its transcription after an oncogenic change might help in the search for new biomarkers. Lung cancer was selected as target since it is ... -
Construction of miRNA–mRNA networks for the identification of lung cancer biomarkers in liquid biopsies
Espinosa García, Elena María; Arroyo Varela, Macarena; Larrosa-Jiménez, Rafael; Gómez‑Maldonado, Josefa; Cobo Dols, Manuel Ángel; Claros-Díaz, Manuel Gonzalo; Bautista-Moreno, Rocío[et al.] (Springer Nature, 2022-10-12)Lung cancer (LC) is the most common cause of cancer death worldwide mostly due to the low survival rate: 75% of cases are identified in advanced stages. In this study, the list of useful biomarkers to make an early diagnosis ... -
Creación y uso de los flujos de trabajo bioinformáticos
Seoane Zonjic, Pedro (UMA Editorial, 2016)En el año 2012 comencé mi doctorado en el Departamento de Biología Molecular y Bioquímica, aunque alojado en la Plataforma Andaluza de Bioinformática (PAB), emplazado en el edificio de Supercomputación y Bioinnovación sito ... -
Importancia de la bioinformática en la implementación de la medicina personalizada de precisión en los sistemas sanitarios: el caso del cáncer de pulmón
Aguilera-Cobos, Lorena (UMA Editorial, 2023)Esta tesis doctoral aborda la medicina personalizada de precisión (MPP) en distintas fases de su desarrollo, desde la investigación hasta la implementación en la rutina clínica, y desde distintos enfoques. Este trabajo ... -
Insights into ROS‐dependent signalling underlying transcriptomic plant responses to the herbicide 2,4‐D
Romero Puertas, María C.; Peláez-Vico, María Ángeles; Pazmiño, Diana M.; Rodríguez Serrano, María; Terrón Camero, Laura; Bautista-Moreno, Rocío; Gómez-Cadenas, Aurelio; Claros-Díaz, Manuel Gonzalo; León, José; Sandalio, Luisa M.[et al.] (Plant Cell & Environment, 2022)The synthetic auxin 2,4-dichlorophenoxyacetic acid (2,4-D) functions as an agronomic weed control herbicide. High concentrations of 2,4-D induce plant growth defects, particularly leaf epinasty and stem curvature. Although ... -
Nitric oxide-dependent regulation of sweet pepper fruit ripening
Claros-Díaz, Manuel Gonzalo; González-Gordo, Salvador; Bautista-Moreno, Rocío; Cañas, Amanda; Palma, José M.; Corpas, Francisco J.[et al.] (Journal of Experimental Botany, 2019)Ripening is a complex physiological process that involves changes in reactive nitrogen and oxygen species that govern the shelf-life and quality of fruits. Nitric oxide (NO)-dependent changes in the sweet pepper fruit ... -
OliveAtlas: a gene expression atlas tool for olea europaea
Bullones, Amanda; Castro, Antonio Jesús; Lima-Cabello, Elena; Alché, Juan de Dios; Luque, Francisco; Claros-Díaz, Manuel Gonzalo; Fernández-Pozo, Noé[et al.] (MDPI, 2023-03-10)The olive (Olea europaea L.) is an ancient crop of great importance in the Mediterranean basin due to the production of olive oil and table olives, which are important sources of fat and have benefits for human health. ... -
Regulatory role of microRNA in mesenteric lymph nodes after Salmonella Typhimurium infection
Claros-Díaz, Manuel Gonzalo; Herrera‐Uribe, Juber; Zaldívar‐López, Sara; Aguilar, Carmen; Luque, Cristina; Bautista-Moreno, Rocío; Carvajal, Ana; Garrido, Juan José[et al.] (Veterinary Research, 2018)Salmonellosis is a gastrointestinal disease caused by non‐typhoidal Salmonella serovars such as Salmonella Typhimu‐ rium. This pathology is a zoonosis, and food animals with subclinical infection constitute a vast reservoir ... -
Transcriptomic Insight into the Pollen Tube Growth of Olea europaea L. subsp. europaea Reveals Reprogramming and Pollen-Specific Genes Including New Transcription Factors
Claros-Díaz, Manuel Gonzalo; Bullones, Amanda; Castro, Antonio Jesús; Lima-Cabello, Elena; Fernández-Pozo, Noé; Bautista, Rocío; Alché, Juan de Dios[et al.] (Plants, 2023)The pollen tube is a key innovation ofland plants that is essential for successful fertilisation. Its development and growth have been profusely studied in model organisms, but in spite of the economic impact of olive ... -
TransFlow: a modular framework for assembling and assessing accurate de novo transcriptomes in non-model organisms
Claros-Díaz, Manuel Gonzalo; Seoane, Pedro; Espigares, Marina; Carmona, Rosario; Polonio, Álvaro; Quintana, Julia; Cretazzo, Enrico; Bota, Josefina; Pérez-García, Alejandro; Alché, Juan de Dios; Gómez, Luis[et al.] (BMC Bioinformatics, 2018)The advances in high-throughput sequencing technologies are allowing more and more de novo assembling of transcriptomes from many new organisms. Some degree of automation and evaluation is required to warrant reproducibility, ...