Listar Biología Molecular y Bioquímica - (BMB) por título
Mostrando ítems 415-434 de 535
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QTLs mapping for primary metabolites responsible of the organoleptic and nutritional characteristics of strawberry (Fragaria x ananassa)
Pott, Delphine; Vallarino Castro, José G.; Medina, Juan Jesús; Fernie, Alisdair R; Amaya Saavedra, Iraida; Osorio-Algar, Sonia
[et al.] (2016-07-01)
The cultivated strawberry (Fragaria x ananassa) is the berry fruit most consumed worldwide and is well-known for its delicate flavour and nutritional properties. However, fruit quality attributes have been lost or reduced ... -
La química médica como fuente de identificación y optimización de compuestos útiles en la biología molecular y celular. Ligandos de tubulina en el sitio de unión de colchicina como agentes antivasculares tumorales.
(2015-01-08)La química médica es una ciencia altamente multidisciplinar que abarca desde el diseño, identificación, síntesis y optimización de compuestos biológicamente activos a la interpretación de su modo de acción a nivel molecular. ... -
Ratones knock-out del receptor lpa1 de ácido lisofosfatídico presentan un acusado déficit de la isoenzima glutaminasa KGA (GLS) y una morfología alterada en las espinas dendríticas de hipocampo y corteza
Peñalver, Ana; Campos-Sandoval, José Ángel; Sánchez-Varo, Raquel María; Cardona Ramírez, Carolina; Castilla, Laura; Blanco, Eduardo; Martín-Rufián, Mercedes; Segura-Checa, Juan Antonio; Mates-Sánchez, José Manuel; Alonso-Carrión, Francisco José; Gutiérrez-Pérez, Antonia; Rodriguez-de-Fonseca, Fernando; Márquez-Gómez, Javier[et al.] (2015-09-25)
Objectives: The objective of the present study was to utilize mice with knocked-down lysophosphatidic acid 1 (LPA1) receptor to ascertain changes in glutamatergic transmission that may help to explain part of the cognitive ... -
ReadqPCR and NormqPCR: R packages for the reading, quality checking and normalisation of RT-qPCR quantification cycle (Cq) data
(BMC, 2012-07)Background: Measuring gene transcription using real-time reverse transcription polymerase chain reaction (RT-qPCR) technology is a mainstay of molecular biology. Technologies now exist to measure the abundance of many ... -
Regulación coordinada de los genes implicados en la síntesis de fenilalanina en pino
Craven-Bartle, Blanca; Pascual-Moreno, María Belén; Cánovas-Ramos, Francisco Miguel; Ávila-Sáez, Concepción (2013-11-04)
Regulación coordinada de los genes implicados en la síntesis de Fenilalanina en pino Craven-Bartle B, Pascual MB, Cánovas FM, Avila C Departamento de Biología Molecular y Bioquímica, Facultad de Ciencias, Campus ... -
Regulación Transcripciones del Gen GLS2 y Obtención de Células Madre Embrionarias Transformadas para Generación de Ratones Knockout
(Servicio de Publicaciones y Divulgación Científica, 2016)La enzima glutaminasa activada por fosfato (GA) cataliza la hidrólisis del grupo amido de la glutamina (Gln) para rendir glutamato (Glu) y amonio. Esta enzima es esencial para el ciclo Gln-Glu entre neuronas y astrocitos ... -
REGULATION OF VITAMIN C BIOSYNTHESIS IN HIGHER PLANTS
Fenech-Torres, Mario; Amorim-Silva, Vitor; Castillo-Garriga, Araceli; Esteban del Valle, Alicia; Valpuesta-Fernández, Victoriano; Smirnoff, Nicholas; Botella-Mesa, Miguel Ángel[et al.] (2019-05-15)
Ascorbate, also known as vitamin C, plays fundamental roles in biotic and abiotic stress resistance in plants. In green tissues, ascorbate is mainly synthesized through the Smirnoff-Wheeler pathway, whose regulation is not ... -
Regulation of Vitamin C content in higher plants
Fenech-Torres, Mario; Amorim-Silva, Vitor; Smirnoff, Nicholas; Botella-Mesa, Miguel Ángel (2017-06-23)
Ascorbic Acid (AsA, vitamin C) has multiple biological roles in plants. Although several pathways for the novo synthesis of AsA have been reported, it is the L-Gal, also known as the Smirnoff-Wheeler (SW), the main pathway ... -
Regulation versus deregulation: an evolutionary perspective on the biochemical control of amino acids biosynthesis in plants
El-Azaz-Ciudad, Jorge; De-la-Torre-Fazio, Fernando Nicolás; Urbano-Gámez, Jose Alberto; Barcelona, Belén; Ávila-Sáez, Concepción; Cánovas-Ramos, Francisco Miguel[et al.] (2019-07-23)
Amino acids are essential compounds for all the living organisms. Along with their central role as constituents of proteins, in plants they also act as precursors of a myriad of compounds and meta- bolites with critical ... -
Regulatory role of microRNA in mesenteric lymph nodes after Salmonella Typhimurium infection
Claros-Díaz, Manuel Gonzalo; Herrera‐Uribe, Juber; Zaldívar‐López, Sara; Aguilar, Carmen; Luque, Cristina; Bautista-Moreno, Rocío; Carvajal, Ana; Garrido, Juan José[et al.] (Veterinary Research, 2018)
Salmonellosis is a gastrointestinal disease caused by non‐typhoidal Salmonella serovars such as Salmonella Typhimu‐ rium. This pathology is a zoonosis, and food animals with subclinical infection constitute a vast reservoir ... -
Regulatory variants: from detection to predicting impact.
(Oxford Academic, 2018-06-08)Variants within non-coding genomic regions can greatly affect disease. In recent years, increasing focus has been given to these variants, and how they can alter regulatory elements, such as enhancers, transcription factor ... -
Repercusiones renales del ejercicio físico intenso. Estudio bioquímico-antropométrico en nadadores adolescentes
(Universidad de Málaga, Servicio de Publicaciones, 1997)Con el objetivo de conocer las repercusiones renales del ejercicio físico intenso en nadadores adolescentes tras la realización de un test de campo en un medio de entrenamiento habitual, se determinaron las tasas de ... -
Rising to the Challenge: Developing Biosensors to Study Nitrogen Transport in Plants
Nitrogen (N) plays a crucial role in plant development and growth, which is why high concentrations of N in the form of fertilizers are commonly used in agricultural crops. However, the excess N present in fertilizers is ... -
Role and therapeutic potential of dietary ketone bodies in lymph vessel growth
(2021-06-02)Lymphatic vessels (LVs), lined by lymphatic endothelial cells (LECs), are indispensable for life. However, the role of metabolism in LECs has been incompletely elucidated. In our study, it is reported that LEC-specific ... -
Role and therapeutic potential of dietary ketone bodies in lymph vessel growth.
(Nature, 2019-07-19)Los vasos linfáticos (LV), revestidos por células endoteliales linfáticas (LEC), son indispensables para la vida1. Sin embargo, el papel del metabolismo en las LEC no se ha dilucidado por completo. En el presente estudio, ... -
Role of Arabidopsis DGK1 and DGK2 in cold stress
García-Hernández, Selene; Ruiz-López, Noemí; Botella-Mesa, Miguel Ángel (2022-09-14)
There are regions, present in all eukaryotic cells, where the membranes of two different organelles are very close (10-30nm), but without fusion, due to proteins which act as tether. These regions are named Membrane Contact ... -
Role of enhancer activity and chromatin architecture on the regulation and evolution of developmental gene expression: The HoxD cluster paradigm.
(2022)Los genes Hox, también conocidos como genes arquitecto por su papel en la especificación del bauplan de vertebrados e invertebrados, se expresan en distintas combinaciones en varias estructuras embrionarias. Estudiando la ... -
Role of glucose, glutamine and palmitate in endothelial and tumor metabolism
Ocaña Farfán, María del Carmen; Martínez-Póveda, Beatriz Amparo; Rodríguez-Quesada, Ana María; Medina-Torres, Miguel Ángel (2016-12-22)
Glucose and glutamine are the major sources of energy for mammalian cells. In tumors, Warburg effect and glutaminolysis have been largely studied. On the other hand, a major role of glucose in angiogenesis has been ... -
Role of ripe fruit epidermis-specific FvMYB29-FvbHLH transcription factor complexes in strawberry
Sánchez-Gómez, Carlos; Perotti, María Florencia; Meco, Victoriano; Domínguez, Eva; Heredia-Bayona, Antonio; Bayer, Emmanuelle M.; Franco-Zorrila, José Manuel; Martín-Pizarro, Carmen; Posé-Padilla, David[et al.] (2023-07-09)
Transcriptome changes during strawberry fruit ripening have been previously reported. However, we have identified genes with tissue- and stage-specific patterns in the receptacles of Fragaria vesca coupling LCM with RNA-seq ... -
Role pf TTLs proteins in cellulose biosynthesis
García-Moreno, Álvaro; Amorim-Silva, Vitor; Valpuesta-Fernández, Victoriano; Macho, Alberto P.; Jaillais, Yvon; Botella-Mesa, Miguel Ángel[et al.] (2018-07-18)
Abiotic stress cause detrimental yield losses in crop species. Plants are sessile organisms, so the understanding of the plant cell wall, which is the most important component that constitute the plant biomass of crop ...