Listar Biología Molecular y Bioquímica - (BMB) por título
Mostrando ítems 398-417 de 479
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Scaffold-mediated Assembly of the Brassinosteroid Signaling Components by TTL proteins
Amorim-Silva, Vitor; García-Moreno, Álvaro; Lakhssassi, Naoufal; Esteban del Valle, Alicia; Rosado Rey, Abel; Pérez-Sancho, Jessica; Li, Yansha; Castillo-Garriga, Araceli
; Pérez-Rodríguez, Josefa; Valpuesta-Fernández, Victoriano; Zipfel, Cyril; Macho, Alberto P.; Botella-Mesa, Miguel Ángel[et al.] (2017-06-23)
Brassinosteroids (BRs) is a group of steroidal hormones that play critical roles in multiple aspects of plant growth and development. BR stimulation at the PM receptors initiates a series of phosphorylation events enabling ... -
Screening of Synergic Interactions of Anti-Angiogenic and Anti-Tumor Compounds
García-Vilas García, Javier Alejandro; Rodríguez-Quesada, Ana María; Medina-Torres, Miguel Ángel (2015-09-30)
Solid cancers have several common characteristics that Hanahan & Weinberg named as the hallmarks of cancer. Angiogenesis is an essential hallmark of cancer because tumor cells need oxygen and nutrients delivered by the ... -
Screening of Synergistic Interactions of Epigallocatechin-3-gallate with Antiangiogenic and Antitumor Compounds
Rodríguez-Quesada, Ana María; Medina-Torres, Miguel Ángel; García-Vilas García, Javier Alejandro (Elsevier, 2016-07)
Purpose: To screen for possible synergistic interactions of epigallocatechin-3-gallate (EGCG) with a selection of 10 anti-angiogenic or anti-tumor compounds on the survival of endothelial and tumor cells. Methods: Human ... -
Search of candidate genes involved in branched-chain amino acid metabolism in strawberry: functional validation
Romero, Helena; Pott, Delphine; Segado, Enrique; Vallarino Castro, José G.; Osorio-Algar, Sonia (2022)
Cultivated strawberry (Fragaria × ananassa) is a berry crop widely appreciated worldwide due to its nutritional and organoleptic properties. However, the main breeding targets in these crops have been the control of ... -
Secretory Profile of Adipose-Tissue-Derived Mesenchymal Stem Cells from Cats with Calicivirus-Positive Severe Chronic Gingivostomatitis
Villatoro, Antonio J.; Martín Astorga, María del Carmen; Alcoholado Cueto, Cristina; Kazantseva, Liliya; Cárdenas García, Casimiro; Fariñas Guerrero, Fernando; Becerra-Ratia, José; Visser, Rick[et al.] (IOAP-MPDI, 2022-05-25)
The feline calicivirus (FCV) causes infections in cats all over the world and seems to be related to a broad variety of clinical presentations, such as feline chronic gingivostomatitis (FCGS), a severe oral pathology in ... -
Selected problems/cases to stimulate collaborative learning regarding the dynamic flexibility of metabolism.
Metabolic reprogramming has been identified as one of the hallmarks of cancer. Furthermore, it is becoming more and more frequent to establish connection between other diseases and metabolic rewiring. One of us has recently ... -
Sensitivity of polyamine metabolism to glucose deprivation is increased in neuroblastoma cells with N-myc amplification
Ruiz-Pérez, M. Victoria; Urdiales-Ruiz, José Luis; Sánchez-Jiménez, Francisca María; Medina-Torres, Miguel Ángel (2014-07-10)
Ornithine-derived polyamines are essential for cell proliferation, and their levels are elevated in many human tumors. Neuroblastoma, the most frequent extra-cranial solid tumor in children, harbors amplification of n-myc ... -
Síndrome de deficiencia de Coenzima Q10
(2017-05-31)Desde 1984 he estado interesado en estudiar las funciones y los mecanismos moleculares de la síntesis de coenzima Q, su regulación y su implicación en la organización y funcionamiento de la cadena respiratoria. En los ... -
SMP-containing proteins at membrane contact sites: subcellular localization and characterization.
Huércano Rubens, Carolina; Percio-Vargas, Francisco; Sánchez-Vera, Victoria; Morello-López, Jorge; Botella-Mesa, Miguel Ángel; Ruiz-López, Noemí[et al.] (2021)
Membrane contact sites (MCS) are microdomains where two membranes of two different organelles are in close apposition, but they do not fuse. MCS are essential for non-vesicular transport of lipids. This lipid transport is ... -
La sobreexpresión del factor de transcripción de pino PpDof5 conduce a un incremento en el contenido de lignina y afecta al metabolismo del carbono y del nitrógeno en Arabidopsis
Rueda-Lopez, Marina; Cañas-Pendón, Rafael Antonio; Canales, Javier; Cánovas-Ramos, Francisco Miguel; Ávila-Sáez, Concepción (2016-02-11)
PpDof 5 es un regulador de la expresión de los genes de glutamina sintetasa de pino tanto en tejidos fotosintéticos como no fotosintéticos. Hemos utilizado Arabidopsis thalianacomo un sistema modelo para estudiar la función ... -
Strawberry GRN forever: insights into the transcriptional regulatory network controlling strawberry fruit ripening and quality
Martín-Pizarro, Carmen; Sánchez-Gómez, Carlos; Meco, Victoriano; Urrutia, María; Pillet, Jeremy; Lucas Reina, Eva; Trapero-Mozos, Almudena; Vallarino Castro, José G.; De Luis Balaguer, María Angels; Pérez-Sancho, Jessica; Bayer, Emmanuelle M.; Franco-Zorrila, José Manuel; Osorio-Algar, Sonia; Sozzani, Rosangela; Botella-Mesa, Miguel Ángel; Valpuesta-Fernández, Victoriano; Posé-Padilla, David[et al.] (2022-07-01)
Ripening is a critical step for the development of flavor quality in fruits. This character has significantly declined in many fleshy fruits over recent decades. This is particularly significant in strawberry (Fragaria × ... -
Structural and functional interaction between polyamine related molecules and biological membranes
Acosta-Andrade, Carlos; Artetxe, I; Lete, MG; Ruiz-Mirazo, Kepa; Goñi, Félix; Urdiales-Ruiz, José Luis; Fajardo-Paredes, Ignacio José; Sánchez-Jiménez, Francisca María[et al.] (2016-09-22)
Changes induced by PA on nucleic acid (NA) conformation and synthesis is proven to be a major reason for PA essentiality (1-3). However, PA interactions with other polyanions, for instance polyanionic membrane lipid bilayers ... -
Structural Bases for the Allergenicity of Fra a 1.02 in Strawberry Fruits.
Orozco-Navarrete, Begoña; Kaczmarska, Zuzanna; Dupeux, Florine; Garrido-Arandia, María; Pott, Delphine; Díaz-Perales, Araceli; Casañal, Ana; Márquez, José A.; Valpuesta-Fernández, Victoriano; Merchante-Berg, Catharina[et al.] (American Chemical Society, 2019-11-27)
Although strawberries are highly appreciated fruits, their intake can induce allergic reactions in atopic patients. These reactions can be due to the patient’s previous sensitization to the major birch pollen allergen Bet ... -
Structural basis of the allergenicity to strawberries due to Fra a 1.02
Orozco-Navarrete, Begoña; Dupeux, Florine; Pott, Delphine; Casañal, Ana; Garrido-Arandia, María; Díaz-Perales, Araceli; Merchante-Berg, Catharina; Márquez, José A.; Valpuesta-Fernández, Victoriano[et al.] (2018-07-13)
Strawberry fruits are highly valued due to their flavor, aroma, and benefits for human health. Despite this, 30% of the population with food hypersensitivity also shows adverse reactions to strawberry (Franz-Oberdorf et ... -
Study of Bioactive Compounds Extracted From Natural Products with Effects on Angiogenesis, Inflammation and Tumor Development
(Universidad de Málaga, Servicio de Publicaciones y Divulgación Científica, 2014)Durante el curso de esta tesis se han generado cuatro artículos de investigación y un capítulo de libro. A continuación se muestra un resumen de sus resultados y conclusiones. En el primer trabajo de investigación, ... -
Study of comorbidity networks among pathological phenotypes in patients with rare genomic disorders
(UMA Editorial, 2022)Durante el desarrollo de esta tesis doctoral se han utilizado aproximaciones de la biología de sistemas para estudiar y caracterizar las relaciones comórbidas entre fenotipos relacionados con enfermedades genéticas raras ... -
Study of the antitumor potential of stauprimide in breast cancer
Carrillo Fernández, Paloma; Téllez Quijorna, Clara; Bernal, Manuel; Rodríguez-Quesada, Ana María; Medina-Torres, Miguel Ángel; Martínez-Póveda, Beatriz Amparo[et al.] (2021)
Stauprimide, a semi-synthetic derivative of staurosporine, was characterized in 2009 as a potent differentiation-enhancing compound in embryonic stem cells [1]. Although it was first thought that this compound could maintain ... -
Study of the NPF and NRT transporter families in the conifer Pinus pinaster
Valderrama-Martín, José Miguel; Ortigosa, Francisco; Ávila-Sáez, Concepción; Cánovas-Ramos, Francisco Miguel; Cañas-Pendón, Rafael Antonio (2019-07-29)
Nitrogen, in natural environments, is the main limiting nutrient for plant growth and development1. This essential element can be presented in different forms in the soils being the two main forms nitrate and ammonium, ... -
Study of Transcriptional Regulatory Network Controlling Strawberry Fruit Ripening and Quality
Martín-Pizarro, Carmen; Lucas-Reina, Eva; Trapero-Mozos, Almudena; Meco, Victoriano; Posé-Padilla, David (2018-07-12)
Ripening is a critical step for the development of flavor quality in fruits. This character has significantly declined in many fleshy fruits over recent decades. This is particularly significant in strawberry (Fragaria × ... -
Study of Transcriptional Regulatory Network Controlling Strawberry Fruit Ripening and Quality
Martín-Pizarro, Carmen; Urrutia, María; Meco, Victoriano; Sánchez-Gómez, Carlos; Pillet, Jeremy; Lucas-Reina, Eva; Trapero-Mozos, Almudena; Vallarino Castro, José G.; De Luis Balaguer, María Angels; Rambla, José Luis; Toivainen, Tuomas; Osorio-Algar, Sonia; Sozzani, Rosangela; Botella-Mesa, Miguel Ángel; Granell, Antonio; Hytönen, Timo; Valpuesta-Fernández, Victoriano; Posé-Padilla, David[et al.] (2021-01-19)
Ripening is a critical step for the development of flavor quality in fruits. This character has significantly declined in many fleshy fruits over recent decades. This is particularly significant in strawberry (Fragaria × ...