Listar Biología Molecular y Bioquímica - (BMB) por título
Mostrando ítems 225-244 de 266
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Scaffold-mediated Assembly of the Brassinosteroid Signaling Components by TTL proteins
(2017-06-23)Brassinosteroids (BRs) is a group of steroidal hormones that play critical roles in multiple aspects of plant growth and development. BR stimulation at the PM receptors initiates a series of phosphorylation events enabling ... -
Screening of Synergic Interactions of Anti-Angiogenic and Anti-Tumor Compounds
(2015-09-30)Solid cancers have several common characteristics that Hanahan & Weinberg named as the hallmarks of cancer. Angiogenesis is an essential hallmark of cancer because tumor cells need oxygen and nutrients delivered by the ... -
Screening of Synergistic Interactions of Epigallocatechin-3-gallate with Antiangiogenic and Antitumor Compounds
(Elsevier, 2016-07)Purpose: To screen for possible synergistic interactions of epigallocatechin-3-gallate (EGCG) with a selection of 10 anti-angiogenic or anti-tumor compounds on the survival of endothelial and tumor cells. Methods: Human ... -
Sensitivity of polyamine metabolism to glucose deprivation is increased in neuroblastoma cells with N-myc amplification
(2014-07-10)Ornithine-derived polyamines are essential for cell proliferation, and their levels are elevated in many human tumors. Neuroblastoma, the most frequent extra-cranial solid tumor in children, harbors amplification of n-myc ... -
Síndrome de deficiencia de Coenzima Q10
(2017-05-31)Desde 1984 he estado interesado en estudiar las funciones y los mecanismos moleculares de la síntesis de coenzima Q, su regulación y su implicación en la organización y funcionamiento de la cadena respiratoria. En los ... -
SMP-CONTAINING PROTEINS AT MEMBRANE CONTACT SITES: SUBCELLULAR LOCALIZATION AND CHARACTERIZATION.
(2021)Membrane contact sites (MCS) are microdomains where two membranes of two different organelles are in close apposition, but they do not fuse. MCS are essential for non-vesicular transport of lipids. This lipid transport is ... -
La sobreexpresión del factor de transcripción de pino PpDof5 conduce a un incremento en el contenido de lignina y afecta al metabolismo del carbono y del nitrógeno en Arabidopsis
(2016-02-11)PpDof 5 es un regulador de la expresión de los genes de glutamina sintetasa de pino tanto en tejidos fotosintéticos como no fotosintéticos. Hemos utilizado Arabidopsis thalianacomo un sistema modelo para estudiar la función ... -
Structural and functional interaction between polyamine related molecules and biological membranes
(2016-09-22)Changes induced by PA on nucleic acid (NA) conformation and synthesis is proven to be a major reason for PA essentiality (1-3). However, PA interactions with other polyanions, for instance polyanionic membrane lipid bilayers ... -
Structural basis of the allergenicity to strawberries due to Fra a 1.02
(2018-07-13)Strawberry fruits are highly valued due to their flavor, aroma, and benefits for human health. Despite this, 30% of the population with food hypersensitivity also shows adverse reactions to strawberry (Franz-Oberdorf et ... -
Study of Bioactive Compounds Extracted From Natural Products with Effects on Angiogenesis, Inflammation and Tumor Development
(Universidad de Málaga, Servicio de Publicaciones y Divulgación Científica, 2014)Durante el curso de esta tesis se han generado cuatro artículos de investigación y un capítulo de libro. A continuación se muestra un resumen de sus resultados y conclusiones. En el primer trabajo de investigación, ... -
Study of the antitumor potential of stauprimide in breast cancer
(2021)Stauprimide, a semi-synthetic derivative of staurosporine, was characterized in 2009 as a potent differentiation-enhancing compound in embryonic stem cells [1]. Although it was first thought that this compound could maintain ... -
Study of the NPF and NRT transporter families in the conifer Pinus pinaster
(2019-07-29)Nitrogen, in natural environments, is the main limiting nutrient for plant growth and development1. This essential element can be presented in different forms in the soils being the two main forms nitrate and ammonium, ... -
Study of Transcriptional Regulatory Network Controlling Strawberry Fruit Ripening and Quality
(2018-07-12)Ripening is a critical step for the development of flavor quality in fruits. This character has significantly declined in many fleshy fruits over recent decades. This is particularly significant in strawberry (Fragaria × ... -
Study of Transcriptional Regulatory Network Controlling Strawberry Fruit Ripening and Quality
(2021-01-19)Ripening is a critical step for the development of flavor quality in fruits. This character has significantly declined in many fleshy fruits over recent decades. This is particularly significant in strawberry (Fragaria × ... -
Studying the role of the strawberry Fra protein family in the flavonoid metabolism during fruit ripening
(2017-06-20)Strawberry fruits are highly valued due to their flavor, aroma and benefits for human health. Much of these properties are due to their content in secondary metabolites, of which flavonoids are especially abundant. ... -
Studying the role of the strawberry Fra protein family in the flavonoid metabolism during fruit ripening
(XIII REUNIÓN DE BIOLOGÍA MOLECULAR DE PLANTAS, 2016)Strawberry fruits are highly appreciated worldwide due to their pleasant flavor and aroma and to the health benefits associated to their consumption. An important part of these properties is due to their content in secondary ... -
Sugar deficiency causes changes in cuticle permeability and cell wall composition that influence fruit postharvest shelf-life
(2014-06-18)The cuticle is a protective layer synthesized by epidermal cells of the plants and consisting of cutin covered and filled by waxes. In tomato (Solanum lycopersicum) fruit, the thick cuticle embedding epidermal cells has ... -
Synaptotagmin1 regulates membrane fusion events that are essential for abiotic stress tolerance in plants
(2013-11-26)Plants undergo continuous exposure to various abiotic stresses in their natural environment. For this reason they have evolved intricate mechanisms to perceive external signals and trigger the physiological changes necessary ... -
Synthetic and molecular genetic approaches in plant hormone research
(2019-09-23)Phytohormones govern plant physiology, environmental adaptation and phenotypic plasticity. Hormone auxin is critical for growth at every stage of plant’s life, from seed germination to fruit ripening. We investigated the ... -
Systems Biology Approaches to Evaluate Disease Modularity
(Universidad de Málaga, Servicio de Publicaciones y Divulgación Científica, 2014)Biological systems are in a constant process of innovation as an essential precondition to evolve. For this reason, the emergence of phenotypic variation is an inherent property of complex adaptive systems. Even though ...