Listar Biología Molecular y Bioquímica - (BMB) por título
Mostrando ítems 258-277 de 422
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Mathematical modeling of cancer metabolism
(2018-10-19)Systemic approaches are needed and useful for the study of the very complex issue of cancer. Modeling has a central position in these systemic approaches. Metabolic reprogramming is nowadays acknowledged as an essential ... -
Medida de glucosa en refrescos: una útil herramienta para ilustrar el aprendizaje de los fundamentos del análisis enzimático
(2016-11-02)Es indudable la relevancia que el análisis enzimático tiene en el ámbito de la Bioquímica, la Química Clínica y la Química de la Alimentación, entre otras. En la asignatura “Bioquímica Aplicada” de cuarto curso ... -
Metabolic Adjustments following Glutaminase Inhibition by CB-839 in Glioblastoma Cell Lines
(IOAP-MDPI, 2023-01-15)Glioblastoma multiforme is the most common primary brain tumor. Unfortunately, it is also one of the cancer types that has the worst morbidity and mortality ratios, so new targets and treatments need to be found. The ... -
Metabolic changes through a bacterial enzyme Maleate Isomerase in transgenic Tomato plants reveal the role of organic acids in fruit quality and crop growth.
(2019-05-10)Organic acids are of fundamental importance in all plant species. They have been clearly described to have roles as important as photosynthate, energy production, carbon storage, biosynthesis of amino acids, stomatal ... -
Metabolic changes upon GLS inhibition by CB-839 in glioma cell lines
(2012-07-19)Many tumors use Gln for both energy generation and as a biosynthetic precursor. Glutaminases (GAs) catalyze the first step of glutaminolysis by converting glutamine (Gln) into glutamate and ammonia in the mitochondria. In ... -
Metabolic channeling of phe for lignin biosynthesis in maritime pine
(2017-07-14)Phenylalanine (Phe) is the main precursor of phenylpropanoids biosynthesis in plants. This vast family of Phe-derived compounds can represent more than 30% of captured photosynthetic carbon, playing essential roles in ... -
Metabolic channelingof phe for lignin biosynthesis in maritime pine
(2016-09-02)METABOLIC CHANNELING OF PHE FOR LIGNIN BIOSYNTHESIS IN MARITIME PINE Jorge El-Azaz, Fernando de la Torre, Belén Pascual, Concepción Ávila and Francisco M. Cánovas Departamento de Biología Molecular y Bioquímica, ... -
Metabolic impact of glutaminase isoenzymes modulation on glioma cell lines
(2022)Many tumors use glutamine for both energy generation and as a biosynthetic precursor. Glutaminases (GAs) catalyze the first step of glutaminolysis by converting glutamine (Gln) into glutamate and ammonia in the mitochondria. ... -
Metabolic preference studies in cells of the tumor microenvironment
(2016-10-03)In the last years, the rediscovery of the Warburg effect and high tumoral glutaminolysis has lead to a renewed interest in cancer metabolism. Moreover, recent studies have put some importance in endothelial cells metabolism. ... -
Metabolic Reprogramming in Tumor Endothelial Cells.
(MDPI, 2022-09-21)The dynamic crosstalk between the different components of the tumor microenvironment is critical to determine cancer progression, metastatic dissemination, tumor immunity, and therapeutic responses. Angiogenesis is critical ... -
Metabolic Reprogramming is a Hallmark of Metabolism Itself
(2020-09-23)The reprogramming of metabolism has been identified as one of the hallmarks of cancer. It is becoming more and more frequent to connect other diseases with metabolic reprogramming. This article aims to argue that metabolic ... -
Metabolic studies within the angiogenic microenvironment as a potential target for the treatment of cancer and other angiogenesis dependent diseases
(UMA Editorial, 2020-09-24)La angiogénesis es el proceso de formación de vasos sanguíneos a partir del lecho vascular preexistente. Una angiogénesis insuficiente o excesiva puede llevar al desarrollo de diversas patologías, entre las que se incluye ... -
Metabolism within the tumor microenvironment and its implication on cancer progression: an ongoing therapeutic target
(2018-10-19)Since reprogramming energy metabolism is considered a new hallmark of cancer, tumor metabolism is again in the spotlight of cancer research. Many studies have been carried out and many possible therapies have been developed ... -
Metabolite profiling of postharvest senescence in different strawberry cultivars
(2019-05-10)The cultivated strawberry (Fragaria x ananassa) is the berry most consumed worldwide, being well appreciated for its flavour and nutritional characteristics. However, strawberries possess a very short postharvest shelf-life ... -
Metabolomic characterization of strawberry cultivars during postharvest
(2018-07-12)The cultivated strawberry (Fragaria x ananassa) is the berry most consumed worldwide and is well-known for its delicate flavour and nutritional characteristics. However, strawberries possess a very short postharvest ... -
Metabolomics profiling of strawberry (Fragaria x ananassa) F1 population to characterize flavour and nutritional traits
(2018-02-27)The cultivated strawberry (Fragaria x ananassa) is a highly consumed fruit known for its delicate flavour and nutritional characteristics. However, as fruit quality attributes have been lost after years of traditional ... -
MiARNs angiogénicos en la regulación del tejido adiposo y su relación con el desarrolo de la resistencia a la insulina asociada a la obesidad
(UMA Editorial, 2018-10-02)Según los últimos datos emitidos por la Organización Mundial de la Salud, la obesidad ha alcanzado proporciones epidémicas a nivel mundial. El incremento del índice de masa corporal puede conducir al desarrollo de otras ... -
Minería de datos aplicada a la Microscopía de Sistemas: Estudio de la relación entre las anotaciones fenotípicas y funcionales en células humanas
(UMA Editorial, 2017-10-18)En el ámbito de la Biología Molecular, uno de los métodos tradicionales que se aplica para asignar funciones a los genes se basa en el silenciamiento de los mismos para observar su fenotipo y de ahí, inferir su función. ... -
Modelado y explotación de redes para la caracterización y predicción en sistemas biomédicos
(UMA Editorial, 2019-11)Este trabajo se enmarca dentro del área de la Biología de Sistemas, un campo de la Ciencia relativamente nuevo. Más concretamente, los estudios aquí presentados hacen uso de metodologías de modelado y análisis de sistemas ... -
Modelo de transporte por canales de isopolaridad. Aplicación clínica en biomarcadores nutrientes
(Universidad de Málaga, Servicio de Publicaciones y Divulgación Científica, 2014)La comunidad científica acepta que los lípidos con pequeño peso molecular, hormonas esteroides, atraviesan las membranas plasmáticas por difusión simple. Si los esteroides, cumplieran con este modo de permeación, al ...