Listar Biología Molecular y Bioquímica - (BMB) por título
Mostrando ítems 265-284 de 422
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Metabolic impact of glutaminase isoenzymes modulation on glioma cell lines
(2022)Many tumors use glutamine for both energy generation and as a biosynthetic precursor. Glutaminases (GAs) catalyze the first step of glutaminolysis by converting glutamine (Gln) into glutamate and ammonia in the mitochondria. ... -
Metabolic preference studies in cells of the tumor microenvironment
(2016-10-03)In the last years, the rediscovery of the Warburg effect and high tumoral glutaminolysis has lead to a renewed interest in cancer metabolism. Moreover, recent studies have put some importance in endothelial cells metabolism. ... -
Metabolic Reprogramming in Tumor Endothelial Cells.
(MDPI, 2022-09-21)The dynamic crosstalk between the different components of the tumor microenvironment is critical to determine cancer progression, metastatic dissemination, tumor immunity, and therapeutic responses. Angiogenesis is critical ... -
Metabolic Reprogramming is a Hallmark of Metabolism Itself
(2020-09-23)The reprogramming of metabolism has been identified as one of the hallmarks of cancer. It is becoming more and more frequent to connect other diseases with metabolic reprogramming. This article aims to argue that metabolic ... -
Metabolic studies within the angiogenic microenvironment as a potential target for the treatment of cancer and other angiogenesis dependent diseases
(UMA Editorial, 2020-09-24)La angiogénesis es el proceso de formación de vasos sanguíneos a partir del lecho vascular preexistente. Una angiogénesis insuficiente o excesiva puede llevar al desarrollo de diversas patologías, entre las que se incluye ... -
Metabolism within the tumor microenvironment and its implication on cancer progression: an ongoing therapeutic target
(2018-10-19)Since reprogramming energy metabolism is considered a new hallmark of cancer, tumor metabolism is again in the spotlight of cancer research. Many studies have been carried out and many possible therapies have been developed ... -
Metabolite profiling of postharvest senescence in different strawberry cultivars
(2019-05-10)The cultivated strawberry (Fragaria x ananassa) is the berry most consumed worldwide, being well appreciated for its flavour and nutritional characteristics. However, strawberries possess a very short postharvest shelf-life ... -
Metabolomic characterization of strawberry cultivars during postharvest
(2018-07-12)The cultivated strawberry (Fragaria x ananassa) is the berry most consumed worldwide and is well-known for its delicate flavour and nutritional characteristics. However, strawberries possess a very short postharvest ... -
Metabolomics profiling of strawberry (Fragaria x ananassa) F1 population to characterize flavour and nutritional traits
(2018-02-27)The cultivated strawberry (Fragaria x ananassa) is a highly consumed fruit known for its delicate flavour and nutritional characteristics. However, as fruit quality attributes have been lost after years of traditional ... -
MiARNs angiogénicos en la regulación del tejido adiposo y su relación con el desarrolo de la resistencia a la insulina asociada a la obesidad
(UMA Editorial, 2018-10-02)Según los últimos datos emitidos por la Organización Mundial de la Salud, la obesidad ha alcanzado proporciones epidémicas a nivel mundial. El incremento del índice de masa corporal puede conducir al desarrollo de otras ... -
Minería de datos aplicada a la Microscopía de Sistemas: Estudio de la relación entre las anotaciones fenotípicas y funcionales en células humanas
(UMA Editorial, 2017-10-18)En el ámbito de la Biología Molecular, uno de los métodos tradicionales que se aplica para asignar funciones a los genes se basa en el silenciamiento de los mismos para observar su fenotipo y de ahí, inferir su función. ... -
Modelado y explotación de redes para la caracterización y predicción en sistemas biomédicos
(UMA Editorial, 2019-11)Este trabajo se enmarca dentro del área de la Biología de Sistemas, un campo de la Ciencia relativamente nuevo. Más concretamente, los estudios aquí presentados hacen uso de metodologías de modelado y análisis de sistemas ... -
Modelo de transporte por canales de isopolaridad. Aplicación clínica en biomarcadores nutrientes
(Universidad de Málaga, Servicio de Publicaciones y Divulgación Científica, 2014)La comunidad científica acepta que los lípidos con pequeño peso molecular, hormonas esteroides, atraviesan las membranas plasmáticas por difusión simple. Si los esteroides, cumplieran con este modo de permeación, al ... -
Modelos preclínicos en oncología molecular: hacia una medicina personalizada
(2016-05-09)El objetivo de esta actividad práctica es ilustrar algunos de los modelos preclínicos utilizados en oncología y discutir su aplicación para la implementación en la clínica de tratamientos personalizados dirigidos a dianas ... -
Modification of plant hormone levels and signaling as a tool in plant biotechnology.
(Wiley, 2009-09-23)Plant hormones are signal molecules, present in trace quantities, that act as major regulators of plant growth and development. They are involved in a wide range of processes such as elongation, flowering, root formation ... -
Modulating Vascular Lymphatic Growth in Disease: Current and Potential Pharmacological Approaches for Prevention and Treatment
(Frontiers Media, 2022-04-25)The lymphatic system is part of the circulatory system and it is indispensable for life. In physiological conditions, the main functions assigned to the lymphatic system are the maintenance of the interstitial fluid ... -
Molecular and functional approaches to enhance biomass production in forest trees
(2014-09-26)Forest trees comprise a large group of angiosperm and gymnosperm species that play a crucial role in global carbon fixation, and maintenance of biodiversity. Forest trees are also of great economic importance since they ... -
Molecular and metabolomics techniques for the nutritive and organoleptic quality improvement of strawberry (Fragaria x ananassa)
(UMA Editorial, 2019-10)España ocupa un puesto privilegiado en la producción y exportación de la fresa (Fragaria x ananassa), que es un fruto muy apreciado por su sabor, aroma y valor nutritivo. Sin embargo, ese fruto tiene una bajísima vida ... -
Multidisciplinary teaching of Biotechnology and Omics sciences
(2017-10-27)In the last years, there was a great boom in the Omics fields that have developed as multidisciplinary sciences. They use laboratory techniques related to Biology and Chemistry but also Bioinformatics tools. However, the ... -
Multiomic studies to improve fruit quality of berry fruits
(2019-02-21)In this study we are going to use different omic-techniques to analyze fruits of three species of berries such as strawberry, raspberry and black currant. Berry fruit are well appreciated for their delicate flavor and ...