Listar Biología Molecular y Bioquímica - (BMB) por título
Mostrando ítems 278-297 de 353
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Profiling the Influence of Gene Variants Related to Folate-Mediated One-Carbon Metabolism on the Outcome of In Vitro Fertilization (IVF) with Donor Oocytes in Recipients Receiving Folic Acid Fortification
(IOAP-MPDI, 2022-09-25)Nutritional status and gene polymorphisms of one-carbon metabolism confer a well-known interaction that in pregnant women may affect embryo viability and the health of the newborn. Folate metabolism directly impacts ... -
Protein Functional Families to characterise drug-target interactions.
(Proceedings IWBBIO 2017, 2017)The quest for “magic bullets” has been the driving force in drug discovery during the last two decades. However, the increasing rate of drug failure over this period has occurred concurrently with the assumption that a ... -
QTLs mapping for primary metabolites responsible of the organoleptic and nutritional characteristics of strawberry (Fragaria x ananassa)
(2016-07-01)The cultivated strawberry (Fragaria x ananassa) is the berry fruit most consumed worldwide and is well-known for its delicate flavour and nutritional properties. However, fruit quality attributes have been lost or reduced ... -
La química médica como fuente de identificación y optimización de compuestos útiles en la biología molecular y celular. Ligandos de tubulina en el sitio de unión de colchicina como agentes antivasculares tumorales.
(2015-01-08)La química médica es una ciencia altamente multidisciplinar que abarca desde el diseño, identificación, síntesis y optimización de compuestos biológicamente activos a la interpretación de su modo de acción a nivel molecular. ... -
Ratones knock-out del receptor lpa1 de ácido lisofosfatídico presentan un acusado déficit de la isoenzima glutaminasa KGA (GLS) y una morfología alterada en las espinas dendríticas de hipocampo y corteza
(2015-09-25)Objectives: The objective of the present study was to utilize mice with knocked-down lysophosphatidic acid 1 (LPA1) receptor to ascertain changes in glutamatergic transmission that may help to explain part of the cognitive ... -
Regulación coordinada de los genes implicados en la síntesis de fenilalanina en pino
(2013-11-04)Regulación coordinada de los genes implicados en la síntesis de Fenilalanina en pino Craven-Bartle B, Pascual MB, Cánovas FM, Avila C Departamento de Biología Molecular y Bioquímica, Facultad de Ciencias, Campus ... -
Regulación Transcripciones del Gen GLS2 y Obtención de Células Madre Embrionarias Transformadas para Generación de Ratones Knockout
(Servicio de Publicaciones y Divulgación Científica, 2016)La enzima glutaminasa activada por fosfato (GA) cataliza la hidrólisis del grupo amido de la glutamina (Gln) para rendir glutamato (Glu) y amonio. Esta enzima es esencial para el ciclo Gln-Glu entre neuronas y astrocitos ... -
REGULATION OF VITAMIN C BIOSYNTHESIS IN HIGHER PLANTS
(2019-05-15)Ascorbate, also known as vitamin C, plays fundamental roles in biotic and abiotic stress resistance in plants. In green tissues, ascorbate is mainly synthesized through the Smirnoff-Wheeler pathway, whose regulation is not ... -
Regulation of Vitamin C content in higher plants
(2017-06-23)Ascorbic Acid (AsA, vitamin C) has multiple biological roles in plants. Although several pathways for the novo synthesis of AsA have been reported, it is the L-Gal, also known as the Smirnoff-Wheeler (SW), the main pathway ... -
Regulation versus deregulation: an evolutionary perspective on the biochemical control of amino acids biosynthesis in plants
(2019-07-23)Amino acids are essential compounds for all the living organisms. Along with their central role as constituents of proteins, in plants they also act as precursors of a myriad of compounds and meta- bolites with critical ... -
Repercusiones renales del ejercicio físico intenso. Estudio bioquímico-antropométrico en nadadores adolescentes
(Universidad de Málaga, Servicio de Publicaciones, 1997)Con el objetivo de conocer las repercusiones renales del ejercicio físico intenso en nadadores adolescentes tras la realización de un test de campo en un medio de entrenamiento habitual, se determinaron las tasas de ... -
Role and therapeutic potential of dietary ketone bodies in lymph vessel growth
(2021-06-02)Lymphatic vessels (LVs), lined by lymphatic endothelial cells (LECs), are indispensable for life. However, the role of metabolism in LECs has been incompletely elucidated. In our study, it is reported that LEC-specific ... -
Role of Arabidopsis DGK1 and DGK2 in cold stress
(2022-09-14)There are regions, present in all eukaryotic cells, where the membranes of two different organelles are very close (10-30nm), but without fusion, due to proteins which act as tether. These regions are named Membrane Contact ... -
Role of enhancer activity and chromatin architecture on the regulation and evolution of developmental gene expression: The HoxD cluster paradigm.
(2022)Los genes Hox, también conocidos como genes arquitecto por su papel en la especificación del bauplan de vertebrados e invertebrados, se expresan en distintas combinaciones en varias estructuras embrionarias. Estudiando la ... -
Role of glucose, glutamine and palmitate in endothelial and tumor metabolism
(2016-12-22)Glucose and glutamine are the major sources of energy for mammalian cells. In tumors, Warburg effect and glutaminolysis have been largely studied. On the other hand, a major role of glucose in angiogenesis has been ... -
Role pf TTLs proteins in cellulose biosynthesis
(2018-07-18)Abiotic stress cause detrimental yield losses in crop species. Plants are sessile organisms, so the understanding of the plant cell wall, which is the most important component that constitute the plant biomass of crop ... -
Root and shoot growth of Pinus strobus x P. wallichiana somatic plants is influenced by the nitrogen composition of the germination medium
(2013-11-07)Somatic embryogenesis (SE) in conifers has proven to be an useful biotechnological tool for species conservation and mass propagation, but to make it commercially viable, adaptive research is required to convert laboratory ... -
Scaffold-mediated Assembly of the Brassinosteroid Signaling Components by TTL proteins
(2017-06-23)Brassinosteroids (BRs) is a group of steroidal hormones that play critical roles in multiple aspects of plant growth and development. BR stimulation at the PM receptors initiates a series of phosphorylation events enabling ... -
Screening of Synergic Interactions of Anti-Angiogenic and Anti-Tumor Compounds
(2015-09-30)Solid cancers have several common characteristics that Hanahan & Weinberg named as the hallmarks of cancer. Angiogenesis is an essential hallmark of cancer because tumor cells need oxygen and nutrients delivered by the ... -
Screening of Synergistic Interactions of Epigallocatechin-3-gallate with Antiangiogenic and Antitumor Compounds
(Elsevier, 2016-07)Purpose: To screen for possible synergistic interactions of epigallocatechin-3-gallate (EGCG) with a selection of 10 anti-angiogenic or anti-tumor compounds on the survival of endothelial and tumor cells. Methods: Human ...