Listar Biología Molecular y Bioquímica - (BMB) por título
Mostrando ítems 317-336 de 422
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Phosphorylation regulates cellulose biosynthesis regulation.
(2023)Plants comprise over 82% of all biomass on Earth, a third of which is cellulose, making it the most abundant organic compound¹. Cellulose is also essential for plant development and defense against multiple stresses. ... -
Pine has two glutamine synthetase paralogs, GS1b.1 and GS1b.2, exhibiting distinct biochemical properties
(Wiley, 2023)The enzyme glutamine synthetase (EC 6.3.1.2) is mainly responsible for the incorporation of inorganic nitrogen into organic molecules in plants. In the present work, a pine (Pinus pinaster) GS1 (PpGS1b.2) gene was identified, ... -
Pining for answers: Study of cationic amino acids (CATs) transport in maritime pine Pinus pinaster Aiton.
(2023)Amino acid (AA) transporters are membrane proteins involved in AA mobilization within and between cells and cells compartments. In plants, these transporters are responsible of AA transport from sink to source organelle/cell ... -
Pitx2; un viaje desde la regulación embrionaria a la arritmogenésis cardiaca
(2017-05-30)Nuestra línea de investigación se ha centrado en diseccionar el papel funcional de factor de transcripción Pitx2 durante en desarrollo cardiovascular y también la miogenesis esquelética. Más recientemente hemos descubierto ... -
Plant microRNAs at the development and defense interface
(2017-04-27)A fascinating biological question is how multicellular organisms maintain their homeostasis by coordinating the different cell types of which they are composed. This task is especially daunting for sessile organisms, like ... -
Plasma membrane lipid remodeling during cold acclimation is mediated by the ER-PM contact sites-localized synaptotagmins 1 and 3
(2016-10-28)Cold acclimation is the capacity of certain plants to increase their freezing tolerance in response to a period of low non-freezing temperatures. Cold acclimation involves a series of biochemical and physiological adaptations, ... -
Polyamines and other biogenic amines at the molecular basis of low prevalence diseases
(2014-09-26)Biogenic amines are amino acid-derived compounds involved in the most important physiological functions: cell proliferation and differentiation, immunity, neurotransmission and neuroendocrine system, fertility. Diseases ... -
Population genomics and gene functional analyses reveal the genetic basis of climate adaptation in woodland strawberry
(2020-12-09)Understanding the genetic basis of climate adaptation on the warming globe is an urgent question from ecological, agricultural and forestry perspectives. Woodland strawberry, the member of the most economically important ... -
Posibles funciones de la familia génica de la glutamato descarboxilasa en Populus
(Servicio de Publicaciones y Divulgación Científica, 2015)Aunque hace más de 50 años que se describió que la glutamato descarboxilasa (GAD) lleva a cabo la descarboxilación del glutamato para producir GABA, y en animales ha sido muy estudiada debido al papel del GABA como ... -
PpNAC1, a main regulator of phenylalanine biosynthesis in p. Pinaster
(2017-07-14)The metabolism of phenylalanine plays a central role in the channeling of carbon from photosynthesis to the biosynthesis of phenylpropanoids duringwood formation. This crucial pathway is finely regulated primarily at ... -
PpNAC1, un regulador principal de la biosíntesis y utilización de fenilalanina en pino
(2018-05-21)La regulación transcripcional del metabolismo de la fenilalanina es particularmente importante en las coníferas, especies de vida larga que usan grandes cantidades de carbono en la formación de madera. El factor de ... -
A practice project to prevent the cookbook model as modus operandi for biochemistry laboratory learning
(2018-07-02)Laboratory learning is a crucial component of chemistry and biochemistry instruction and should be conceived as a way to develop students’ reasoning, technical or practical skills, introducing them into the scientific ... -
A problem-/case-based learning approach as an useful tool for studying glycogen metabolism and its regulation
(2020-09-23)Metabolism and its regulation is one of the most complex and difficult topics for students learning biochemistry. A problem-/case-based learning (PBL) approach can be useful to help biochemistry students to fulfill the ... -
Profiling the Influence of Gene Variants Related to Folate-Mediated One-Carbon Metabolism on the Outcome of In Vitro Fertilization (IVF) with Donor Oocytes in Recipients Receiving Folic Acid Fortification
(IOAP-MPDI, 2022-09-25)Nutritional status and gene polymorphisms of one-carbon metabolism confer a well-known interaction that in pregnant women may affect embryo viability and the health of the newborn. Folate metabolism directly impacts ... -
Protein Functional Families to characterise drug-target interactions.
(Proceedings IWBBIO 2017, 2017)The quest for “magic bullets” has been the driving force in drug discovery during the last two decades. However, the increasing rate of drug failure over this period has occurred concurrently with the assumption that a ... -
Proteome-Wide Structural Computations Provide Insights into Empirical Amino Acid Substitution Matrices
(IOAP-MDPI, 2023-01-02)The relative contribution of mutation and selection to the amino acid substitution rates observed in empirical matrices is unclear. Herein, we present a neutral continuous fitness-stability model, inspired by the Arrhenius ... -
QTLs mapping for primary metabolites responsible of the organoleptic and nutritional characteristics of strawberry (Fragaria x ananassa)
(2016-07-01)The cultivated strawberry (Fragaria x ananassa) is the berry fruit most consumed worldwide and is well-known for its delicate flavour and nutritional properties. However, fruit quality attributes have been lost or reduced ... -
La química médica como fuente de identificación y optimización de compuestos útiles en la biología molecular y celular. Ligandos de tubulina en el sitio de unión de colchicina como agentes antivasculares tumorales.
(2015-01-08)La química médica es una ciencia altamente multidisciplinar que abarca desde el diseño, identificación, síntesis y optimización de compuestos biológicamente activos a la interpretación de su modo de acción a nivel molecular. ... -
Ratones knock-out del receptor lpa1 de ácido lisofosfatídico presentan un acusado déficit de la isoenzima glutaminasa KGA (GLS) y una morfología alterada en las espinas dendríticas de hipocampo y corteza
(2015-09-25)Objectives: The objective of the present study was to utilize mice with knocked-down lysophosphatidic acid 1 (LPA1) receptor to ascertain changes in glutamatergic transmission that may help to explain part of the cognitive ... -
Regulación coordinada de los genes implicados en la síntesis de fenilalanina en pino
(2013-11-04)Regulación coordinada de los genes implicados en la síntesis de Fenilalanina en pino Craven-Bartle B, Pascual MB, Cánovas FM, Avila C Departamento de Biología Molecular y Bioquímica, Facultad de Ciencias, Campus ...