ListarBiología Molecular y Bioquímica - (BMB) por tema "Biología molecular"
Mostrando ítems 1-19 de 19
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A workflow with dedicated tools for preparing reference transcriptomes from non-model organisms has evidenced important biological information
Claros-Díaz, Manuel Gonzalo
; Benzekri, Hicham; Seoane, Pedro; Carmona Muñoz, Rosario Maria; Bautista-Moreno, Rocío; Guerrero-Fernández, Darío; Fernández-Pozo, Noé[et al.] (2014-10-01)
Construction transcriptomes of non-model organisms is a common task nowadays due to the advent of low-cost sequencing platforms. The non-model organisms require a de novo assembling strategy since no reference is available. ... -
Aroma Map in European Woodland Strawberry
Urrutia, María; Meco, Victoriano; Martín-Pizarro, Carmen; Trapero, Almudena; Pillet, Jeremy; Rambla, José Luis; Toivainen, Tuomas; Granell, Antonio; Hytönen, Timo; Posé-Padilla, David[et al.] (2020-01-07)
Woodland strawberry (Fragaria vesca, 2x) is a wild, diploid ancestor of the cultivated strawberry (Fragaria ananassa, 8x), the most economically important berry crop. F. vesca is very appreciated for its intense fruity ... -
Bases genéticas del desarrollo y composición de la cutícula del fruto de tomate
(UMA Editorial, 2022)The plant cuticle, as the interface between the plant and the environment, plays an important role in plant performance, fruit quality and postharvest. Plant cuticles show compositional and structural variability among and ... -
Bioinformatics analysis of Pinus pinaster Aiton transcriptome in response to ammoniacal nutrition
(2019-07-30)Conifers have a great economic and environmental value. Nitrogen is an important limiting factor for the development of plants. Conifers are well adapted to ammonium nutrition since it is the main source of inorganic ... -
Biomarcadores de cáncer de pulmón basados en la expresión de genes, transportes y secuencias repetitivas.
(UMA Editorial, 2020-02-21)Uno de los grandes avances terapéuticos es la medicina personalizada, que se basa en biomarcadores que ayudan en la filiación y elección del tratamiento. La mayoría de los biomarcadores se basan en variaciones génicas y ... -
Caracterización estructural y funcional de la isoenzima glutaminasa GLS2 y su implicación en cáncer
(UMA Editorial, 2022)Las isoenzimas de glutaminasa (GLS y GLS2) catalizan el primer paso de la ruta de la glutaminolisis (conversión de glutamina a glutamato e iones amonio) y desempeñan un papel clave en crecimiento y proliferación del cáncer. ... -
Characterization of ripe fruit epidermis-specific transcription factors in strawberry.
Franco-Zorrila, José Manuel; Posé-Padilla, David; Sánchez-Gómez, Carlos; Martín-Pizarro, Carmen; Bayer, Emmanuelle M.; Pérez-Sancho, Jessica; Castillo-Garriga, Araceli; Urrutia, María; Meco, Victoriano[et al.] (2021)
The epidermis is the external cell layer in direct contact with the environment, and it plays essential biological roles. Transcriptome analysis (RNA-seq) of Fragaria vesca fruit receptacles at four ripening stages (green, ... -
Design and generation of a glutaminase GLS2 conditional knockout mice
Peñalver, Ana; Tosina, Marta; Martín-Rufián, Mercedes; Campos-Sandoval, José Ángel; Alonso-Carrión, Francisco José; Segura-Checa, Juan Antonio; Mates-Sánchez, José Manuel; Ramírez, Miguel Ángel; Gutiérrez-Adán, Alfonso; Márquez-Gómez, Javier[et al.] (2014-10-04)
Mammalian glutaminase (GA; EC 3.5.1.2) is the main enzyme involved in brain generation of glutamate (Glu). This amino acid acts as an excitatory neurotransmitter within the CNS, and it is also implicated in behavioral ... -
Estudio comparativo de las enzimas implicadas en la biosíntesis de arginina a partir de ornitina en plantas
Urbano-Gámez, Jose Alberto; El-Azaz-Ciudad, Jorge; De-la-Torre-Fazio, Fernando Nicolás; Ávila-Sáez, Concepción; Cánovas-Ramos, Francisco Miguel (2022-02-02)
La arginina es un aminoácido presente en todos los organismos cuya función principal es formar parte de la estructura primaria de las proteínas, pero también tiene otros destinos, como la síntesis de poliaminas y óxido ... -
Evaluation of the anti-angiogenic potential of hydroxytyrosol derivatives
Marrero Capitán, Ana Dácil; Martínez-Póveda, Beatriz Amparo; Castilla, Laura; Gallardo, Elena; Espartero Sánchez, José Luis; Carrillo Fernández, Paloma; Rodríguez-Quesada, Ana María; Medina-Torres, Miguel Ángel[et al.] (2018-09-19)
Angiogenesis, a process which allows the formation of new vessels from pre-existing ones, is an essential phenomenon for tumor survival since it allows cancer cells to obtain nutrients and oxygen. This explains the increasing ... -
Identificación y caracterización de genes implicados en la floración y el estolonado en fresa (Fragaria x ananassa Duch.)
(UMA Editorial, 2017)A lo largo de su desarrollo las plantas sufren sucesivas transiciones en respuesta a factores ambientales y endógenos (Albani y Coupland, 2010). La primera transición es el paso del estado juvenil al estado adulto, donde ... -
Identification and functional validation of methyl ketone synthase 2 in woodland strawberry
Tovainen, Tuomas; Sánchez-Gómez, Carlos; Salas, Joaquín; Hytönen, Timo; Posé-Padilla, David; Urrutia, María; Meco, Victoriano; Granell, Antonio; Trapero-Mozos, Almudena; Pillet, Jeremy; Martín-Pizarro, Carmen; Rambla, José Luis[et al.] (2021)
Methyl ketones are compounds with demonstrated insect repellent effects. They are highly abundant in the glandular trichomes of wild tomato (Solanum habrochaites), where their pathway was first described, but not in the ... -
Integration of flowering time signals in Arabidopsis thaliana
(2014-02-27)The induction of flowering is a central event in the life cycle of plants. When timed correctly, it helps ensure reproductive success, and therefore has adaptive value. Because of its importance, flowering is under the ... -
Involvement of a Myb transcription factor in the regulation of phenylalanine pathway in maritime pine
Craven-Bartle, Blanca; Pascual-Moreno, María Belén; Cánovas-Ramos, Francisco Miguel; Ávila-Sáez, Concepción (2013-12-05)
Wood is traditionally among the most important commercial products because of the high demand that exits for its derivatives. Trees, including conifers, divert large quantities of carbon into the biosynthesis of phenylpropanoids, ... -
De la idea al negocio o ¿Cómo montar una startup biotecnológica?
Rodríguez-Caso, Carlos Francisco (2020-01-07)
En la sociedad actual es cada vez más común hablar de emprendimiento. Emprender es afrontar la incertidumbre del desarrollo de un proyecto que generalmente contiene una componente alta de innovación. Las habilidades ... -
Modelos preclínicos en oncología molecular: hacia una medicina personalizada
(2016-05-09)El objetivo de esta actividad práctica es ilustrar algunos de los modelos preclínicos utilizados en oncología y discutir su aplicación para la implementación en la clínica de tratamientos personalizados dirigidos a dianas ... -
Novel dimensionality reduction method, Taelcore, enhances lung transplantation risk prediction
(Elsevier, 2024-01-04)In this work, we present a new approach to predict the risk of acute cellular rejection (ACR) after lung transplantation by using machine learning algorithms, such as Multilayer Perceptron (MLP) or Autoencoder (AE), and ... -
The art of sequence alignment
(2014-02-12)Sequence similarity: why are we interested in, how do you define it Scoring metrics: what is important in similarity Scoring with DNA: integrating biological knowledge Scoring with proteins: integrating biological ... -
TransFlow: a modular framework for assembling and assessing accurate de novo transcriptomes in non-model organisms
Claros-Díaz, Manuel Gonzalo; Seoane, Pedro; Espigares, Marina; Carmona, Rosario; Polonio, Álvaro; Quintana, Julia; Cretazzo, Enrico; Bota, Josefina; Pérez-García, Alejandro; Alché, Juan de Dios; Gómez, Luis[et al.] (BMC Bioinformatics, 2018)
The advances in high-throughput sequencing technologies are allowing more and more de novo assembling of transcriptomes from many new organisms. Some degree of automation and evaluation is required to warrant reproducibility, ...