Listar Biología Molecular y Bioquímica - (BMB) por tipo "info:eu-repo/semantics/conferenceObject"
Mostrando ítems 1-20 de 246
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A central role for bifunctional aspartate/prephenate aminotransferase in the biosynthesis of amino acids in plant plastids.
El-Azaz-Ciudad, Jorge; Canovas-Ramos, Francisco Miguel
; De-la-Torre-Fazio, Fernando Nicolas; Avila-Saez, Concepcion (2014-06-27)
A central role for bifunctional aspartate/prephenate aminotransferase in the biosynthesis of amino acids in plant plastids. Fernando de la Torre, Jorge El-Azaz, Concepción Ávila, Francisco M. Cánovas Departamento de ... -
A network biology approach to novel therapeutic estrategies
(2017-05-30)Network and systems biology offer a novel way of approaching drug discovery by developing models that consider the global physiological environment of protein targets, and the effects of modifying them, without losing the ... -
A role for antizyme inhibitor 2 in the biosynthesis and content of histamine and serotonin in mouse mast cells
Acosta-Andrade, Carlos; Lambertos, Ana; Urdiales-Ruiz, Jose Luis; Sanchez-Jimenez, Francisca Maria; Peñafiel, Rafael; Fajardo-Paredes, Ignacio José[et al.] (2015-09-14)
Polyamines (putrescine, spermidine and spermine; PAs) are required for the survival of the majority of living cells. Antizymes and antizyme inhibitors are key regulatory proteins of PA levels by affecting ornithine ... -
A role for antizyme inhibitor 2 in the biosynthesis and content of serotonin and histamine in mouse mast cells
Acosta-Andrade, Carlos; Lambertos, Ana; Urdiales-Ruiz, Jose Luis; Sanchez-Jimenez, Francisca Maria; Peñafiel, Rafael; Fajardo-Paredes, Ignacio José[et al.] (2015-09-04)
Polyamines (putrescine, spermidine and spermine; PAs) are essential for the majority of living cells. Antizymes and antizyme inhibitors are key regulatory proteins of PA levels by affecting ornithine decarboxylase and PA ... -
A workflow with dedicated tools for preparing reference transcriptomes from non-model organisms has evidenced important biological information
Claros-Diaz, Manuel Gonzalo; Benzekri, Hicham; Seoane, Pedro; Carmona Muñoz, Rosario Maria; Bautista-Moreno, Rocio; Guerrero-Fernández, Darío; Fernández-Pozo, Noé[et al.] (2014-10-01)
Construction transcriptomes of non-model organisms is a common task nowadays due to the advent of low-cost sequencing platforms. The non-model organisms require a de novo assembling strategy since no reference is available. ... -
AD0157, a pyrrolidinedione fungal metabolite, inhibits angiogenesis by targeting the Akt signaling pathway
García-Caballero, Melissa; Cañedo, Librada; Fernández-Medarde, Antonio; Rodriguez-Quesada, Ana Maria; Medina, Miguel Ángel (2014-09-16)
In the course of a screening program for the inhibitors of angiogenesis from marine sources, AD0157, a pyrrolidinedione fungal metabolite, was selected for its angiosupressive properties. AD0157 inhibited the growth of ... -
Algunos aspectos de la evolución de la familia génica de glutamina sintetasa en plantas
Valderrama-Martín, José Miguel; Ortigosa, Francisco; Avila-Saez, Concepcion; Canovas-Ramos, Francisco Miguel; Hirel, Bertrand; Ruiz-Canton, Francisco Javier; Cañas-Pendon, Rafael Antonio[et al.] (2022)
En las plantas, la actividad glutamina sintetasa reside en miembros de la superfamilia GSII, que forman dos grupos de enzimas GS funcionales: la GSIIb eubacteriana (GLN2) y la GSIIe eucariota (GLN1/GS). Los análisis ... -
Allelic variation of MYB10 is the major force controlling natural variation in skin and flesh color in strawberry (Fragaria spp.) fruit
Castillejo, Cristina; Waurich, Veronika; Wagner, Henning; Ramos, Rubén; Oiza, Nicolas; Muñoz, Pilar; Triviño, Juan C; Caruana, Julia; Liu, Zhongchi; Cobo, Nicolás; Hardigan, Michael A; Knapp, Steven J; Vallarino, José G.; Osorio-Algar, Sonia; Martín-Pizarro, Carmen; Pose-Padilla, David; Toivainen, Tuomas; Hytönen, Timo; Oh, Youngjae; Barbey, Christopher R; Whitaker, Vance M; Lee, Seonghee; Olbricht, Klaus; Sánchez-Sevilla, José F; Amaya Saavedra, Iraida[et al.] (2021-11-26)
Fruits of diploid and octoploid strawberry (Fragaria spp.) show substantial natural variation in both skin and flesh color due to distinct anthocyanin accumulation and distribution patterns. Expression of structural genes ... -
Alteration of TCA in transgenic tomato plants shows a crucial role of organic acids in crop development and fruit quality
Jimenez, Lidia; Pott, Delphine; Martinez-Ferri, Elsa; Vallarino, José G.; Osorio-Algar, Sonia (2018-07-12)
Tomato (Solanum lycopersicum) is second most consumed vegetable in the world, but also a model plant for the study of fleshy fruit ripening and senescence owing to its genetic and molecular tractability. Organic acids play ... -
Aminooxi análogos de histidina: una posible estrategia para modular la histidina descarboxilasa humana.
Sanchez-Jimenez, Francisca Maria (2014-09-26)
La histamina (Hia) es una amina biógena implicada en procesos fisiológicos esenciales (respuesta inmune, neurotransmisión y otros). El desequilibrio de su metabolismo juega un destacado papel en muchas patologías. El control ... -
An ecological model of invasion and metastasis
Serrano, José J.; Urdiales-Ruiz, Jose Luis; Medina, Miguel Ángel; Montañez, Raúl (2017-08-29)
It has been argued that malignat tumours represent complex dynamic and self-organizing ecosystems. Furthermore, there is increasing evidence that collective cell migration occurs during invasion and metastasis. Here, we ... -
Análisis de expresión de genes potencialmente implicados en la deposición de la cutícula del fruto en líneas de introgresión de tomate
Mateos del Amo, Juan Carlos; Domínguez Carmona, Eva María; Heredia Bayona, Antonio; Gallardo-Alba, Fernando; Fernández Muñoz, Rafael (Sociedad Española de Ciencias Hortícolas, 2022)
La cutícula vegetal es la capa más externa que cubre los órganos aéreos de las plantas y los protege de la pérdida de agua y del ataque de patógenos, además de determinar rasgos de calidad de fruto como el agrietado o la ... -
Análisis molecular y funcional de los transportadores de amonio (AMT) en pino marítimo (Pinus pinaster)
En los bosques de coníferas la mayor parte del nitrógeno inorgánico disponible se encuentra en forma de amonio como fuente primaria de nitrógeno asimilable [1]. El amonio se incorpora por las raíces a través de proteínas ... -
El análisis transcriptómico de embriones somáticos y cigóticos de pino revela diferencias de expresión en diferentes rutas metabólicas
Avila-Saez, Concepcion; Llebrés, Maria Teresa; Castro-Rodríguez, Vanessa; Trontin, Jean-François; Harvengt, Luc; Canovas-Ramos, Francisco Miguel[et al.] (2022)
La embriogénesis es un proceso complejo en las plantas, pero comprenderlo en las coníferas es especialmente crítico no sólo para poder hacer estudios comparativos con angiospermas sino también para producir embriones viables ... -
Análisis transcriptómico de la eficiencia en la captación de nitrógeno y la producción de biomasa en pino marítimo (Pinus pinaster)
Ortigosa, Francisco; Valderrama-Martín, José Miguel; Avila-Saez, Concepcion; Canovas-Ramos, Francisco Miguel; Cañas-Pendon, Rafael Antonio (2018-05-31)
Las coníferas son un grupo de plantas gimnospermas que forman extensos bosques, principalmente en el hemisferio norte1, por lo que presentan importantes contribuciones ecológicas y económicas. Debido al tipo de suelos en ... -
El análogo de las estrigolactonas GR-24 inhibe la angiogénesis in vitro e in vivo
Carrillo Fernández, Paloma; Martinez-Poveda, Beatriz Amparo; Medina, Miguel Ángel; Rodriguez-Quesada, Ana Maria (2016-10-03)
Muchas fitohormonas han mostrado un gran potencial en la prevención y terapia contra el cáncer. Las estrigolactonas son hormonas vegetales derivadas de los caroteinoides que están implicadas en la inhibición de la ramificación ... -
Analysis of a putative autophagy regulator during strawberry fruit ripening
Peralta-García, Raúl; Montero-Solís, Elena; Valpuesta-Fernandez, Victoriano; Sanchez-Vera, Victoria (2022)
Autophagy is a major catabolic pathway essential for cell homeostasis and conserved in almost all eukaryotes. During autophagy, cytoplasmic components are engulfed by a double membrane vesicle called autophagosome and ... -
Analysis of NPF and NRT transporter families regarding the nitrate nutrition in maritime pine (Pinus pinaster)
Valderrama-Martín, José Miguel; Ortigosa, Francisco; Avila-Saez, Concepcion; Canovas-Ramos, Francisco Miguel; Cañas-Pendon, Rafael Antonio (2019-07-08)
Nitrogen is an essential element for life and the main limiting nutrient for plant growth and development1. The main forms of inorganic nitrogen in soils are nitrate and ammonium, which relative abundances depend on ... -
Anti-inflammatory potential of aeroplysinin-1, a bioactive compound isolated from the sponge Aplysina aerophoba
Bravo-Ruiz, Inés; Bernal, Manuel; Manrique-Poyato, Maria Inmaculada; Rodriguez-Quesada, Ana Maria; Medina Torres, Miguel Ángel; Castilla, Laura; Martinez-Poveda, Beatriz Amparo[et al.] (43 Congreso Anual SEBBM, 2021)
Aeroplysinin-1 (Apl-1) is a brominated compound isolated from the marine sponge Aplysina aerophoba that has been shown to possess bioactive effects with a broad spectrum of action in in vitro and in vivo assays. Included ... -
Antioxidant potential of an anthraquinone metabolite isolated from a marine fungus.
Vidal-Valenzuela, Isabel; Torres-Vargas, José Antonio; García-Caballero, Melissa; Medina, Miguel Ángel; Rodriguez-Quesada, Ana Maria (2023)
Marine ecosystem is a fruitful source of many pharmacologically active. In particular, a number of marine anthraquinones and their derivatives, have been studied for their potential as anticancer and antimetastatic agents, ...