Listar BMB - Artículos por título
Mostrando ítems 68-87 de 96
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Network-Based Methods for Approaching Human Pathologies from a Phenotypic Point of View
(IOAP-MPDI, 2022-06-17)Network and systemic approaches to studying human pathologies are helping us to gain insight into the molecular mechanisms of and potential therapeutic interventions for human diseases, especially for complex diseases where ... -
Nitric oxide-dependent regulation of sweet pepper fruit ripening
Claros-Díaz, Manuel Gonzalo
; González-Gordo, Salvador; Bautista-Moreno, Rocío; Cañas, Amanda; Palma, José M.; Corpas, Francisco J.[et al.] (Journal of Experimental Botany, 2019)
Ripening is a complex physiological process that involves changes in reactive nitrogen and oxygen species that govern the shelf-life and quality of fruits. Nitric oxide (NO)-dependent changes in the sweet pepper fruit ... -
Non-targeted metabolomics characterization of Annona muricata leaf extracts with anti-angiogenic activity
Cárdenas García, Casimiro; Torres-Vargas, José Antonio; Cárdenas Valdivia, Abel; Jurado, Nuria; Rodríguez-Quesada, Ana María; García-Caballero, Melissa; Martínez-Póveda, Beatriz Amparo; Medina-Torres, Miguel Ángel[et al.] (ELSEVIER, 2021-11)
The tropical plant Annona muricata has been widely used for traditional ethnobotanic and pharmacologic applications. Extracts from different parts of this plant have been shown to have a wide range of biological activities. ... -
Novel application assigned to toluquinol: inhibition of lymphangiogenesis by interfering with VEGF-C/VEGFR-3 signalling pathway
García-Caballero, Melissa; Blacher, S.; Pauper, J.; Rodríguez-Quesada, Ana María; Medina-Torres, Miguel Ángel; Noël, Agnès[et al.] (Wiley, 2016)
BACKGROUND AND PURPOSE Lymphangiogenesis is an important biological process associated with the pathogenesis of several diseases, including metastatic dissemination, graft rejection, lymphoedema and other inflammatory ... -
Novel dimensionality reduction method, Taelcore, enhances lung transplantation risk prediction
(Elsevier, 2024-01-04)In this work, we present a new approach to predict the risk of acute cellular rejection (ACR) after lung transplantation by using machine learning algorithms, such as Multilayer Perceptron (MLP) or Autoencoder (AE), and ... -
OliveAtlas: a gene expression atlas tool for olea europaea
Bullones, Amanda; Castro, Antonio Jesús; Lima-Cabello, Elena; Alché, Juan de Dios; Luque, Francisco; Claros-Díaz, Manuel Gonzalo; Fernández-Pozo, Noé[et al.] (MDPI, 2023-03-10)
The olive (Olea europaea L.) is an ancient crop of great importance in the Mediterranean basin due to the production of olive oil and table olives, which are important sources of fat and have benefits for human health. ... -
Physiological, epigenetic and genetic regulation in some olive cultivars under salt stress.
Mousavi, Soraya; Regni, Luca; Bocchini, Marika; Mariotti, Roberto; Cultrera, Nicoló M.; Mancuso, Stefano; Googlani, Jalaladdin; Chakerolhosseini, Mohammad R.; Guerrero-Ruiz, Consolación María; Albertini, Emidio; Baldoni, Luciana; Proietti, Primo[et al.] (Springer Nature, 2019-01-31)
Cultivated olive, a typical fruit crop species of the semi-arid regions, could successfully face the new scenarios driven by the climate change through the selection of tolerant varieties to salt and drought stresses. ... -
Pine has two glutamine synthetase paralogs, GS1b.1 and GS1b.2, exhibiting distinct biochemical properties
Valderrama-Martín, José Miguel; Ortigosa, Francisco; Aledo-Ramos, Juan Carlos; Ávila-Sáez, Concepción; Cánovas-Ramos, Francisco Miguel; Cañas-Pendón, Rafael Antonio[et al.] (Wiley, 2023)
The enzyme glutamine synthetase (EC 6.3.1.2) is mainly responsible for the incorporation of inorganic nitrogen into organic molecules in plants. In the present work, a pine (Pinus pinaster) GS1 (PpGS1b.2) gene was identified, ... -
A problem-/case-based learning approach as an useful tool for studying glycogen metabolism and its regulation
García-Ponce, Ángel Luis; Martínez-Póveda, Beatriz Amparo; Blanco-López, Ángel; Rodríguez-Quesada, Ana María; Suárez-Marín, María Fernanda; Alonso-Carrión, Francisco José; Medina-Torres, Miguel Ángel[et al.] (2020-09-23)
Metabolism and its regulation is one of the most complex and difficult topics for students learning biochemistry. A problem-/case-based learning (PBL) approach can be useful to help biochemistry students to fulfill the ... -
Profiling the Influence of Gene Variants Related to Folate-Mediated One-Carbon Metabolism on the Outcome of In Vitro Fertilization (IVF) with Donor Oocytes in Recipients Receiving Folic Acid Fortification
Reyes Palomares, Arturo Lazaro; Ruiz-Galdón, Maximiliano; Liu, Kui; Reyes-Engel, Armando; Rodriguez-Wallberg, Kenny A. (IOAP-MPDI, 2022-09-25)
Nutritional status and gene polymorphisms of one-carbon metabolism confer a well-known interaction that in pregnant women may affect embryo viability and the health of the newborn. Folate metabolism directly impacts ... -
Proteome-Wide Structural Computations Provide Insights into Empirical Amino Acid Substitution Matrices
Aledo, Pablo; Aledo-Ramos, Juan Carlos (IOAP-MDPI, 2023-01-02)
The relative contribution of mutation and selection to the amino acid substitution rates observed in empirical matrices is unclear. Herein, we present a neutral continuous fitness-stability model, inspired by the Arrhenius ... -
Pyroptosis Modulators: New Insights of Gasdermins in Health and Disease.
Allali-Boumara, Imane; Marrero Capitán, Ana Dácil; Rodríguez-Quesada, Ana María; Martínez-Póveda, Beatriz Amparo; Medina-Torres, Miguel Ángel (MDPI, 2023-08-03)
Pyroptosis is an inflammation-dependent type of cell death that has been in the spotlight for the scientific community in the last few years. Crucial players in the process of pyroptosis are the members of the gasdermin ... -
Regulatory role of microRNA in mesenteric lymph nodes after Salmonella Typhimurium infection
Claros-Díaz, Manuel Gonzalo; Herrera‐Uribe, Juber; Zaldívar‐López, Sara; Aguilar, Carmen; Luque, Cristina; Bautista-Moreno, Rocío; Carvajal, Ana; Garrido, Juan José[et al.] (Veterinary Research, 2018)
Salmonellosis is a gastrointestinal disease caused by non‐typhoidal Salmonella serovars such as Salmonella Typhimu‐ rium. This pathology is a zoonosis, and food animals with subclinical infection constitute a vast reservoir ... -
Screening of Synergistic Interactions of Epigallocatechin-3-gallate with Antiangiogenic and Antitumor Compounds
Rodríguez-Quesada, Ana María; Medina-Torres, Miguel Ángel; García-Vilas García, Javier Alejandro (Elsevier, 2016-07)
Purpose: To screen for possible synergistic interactions of epigallocatechin-3-gallate (EGCG) with a selection of 10 anti-angiogenic or anti-tumor compounds on the survival of endothelial and tumor cells. Methods: Human ... -
Secretory Profile of Adipose-Tissue-Derived Mesenchymal Stem Cells from Cats with Calicivirus-Positive Severe Chronic Gingivostomatitis
Villatoro, Antonio J.; Martín Astorga, María del Carmen; Alcoholado Cueto, Cristina; Kazantseva, Liliya; Cárdenas García, Casimiro; Fariñas Guerrero, Fernando; Becerra-Ratia, José; Visser, Rick[et al.] (IOAP-MPDI, 2022-05-25)
The feline calicivirus (FCV) causes infections in cats all over the world and seems to be related to a broad variety of clinical presentations, such as feline chronic gingivostomatitis (FCGS), a severe oral pathology in ... -
Structural Bases for the Allergenicity of Fra a 1.02 in Strawberry Fruits.
Orozco-Navarrete, Begoña; Kaczmarska, Zuzanna; Dupeux, Florine; Garrido-Arandia, María; Pott, Delphine; Díaz-Perales, Araceli; Casañal, Ana; Márquez, José A.; Valpuesta-Fernández, Victoriano; Merchante-Berg, Catharina[et al.] (American Chemical Society, 2019-11-27)
Although strawberries are highly appreciated fruits, their intake can induce allergic reactions in atopic patients. These reactions can be due to the patient’s previous sensitization to the major birch pollen allergen Bet ... -
Sustainability in the management of scientific information
Medina-Torres, Miguel Ángel (Springer Nature, 2020-09-25)
The sustainability in the management of scientific information is becoming compromised in this new age of Big Data. Herein, I present and discuss some of the main challenges of this situation in both scientific practice ... -
Synthesis, characterization and biological evaluation of octyltrimethylammonium tetrathiotungstate
Vega-Granados, Karla; Cruz-Reyes, Juan; Horta-Marrón, José F.; Mari-Beffa, Manuel; Díaz-Rubio, Laura; Córdova-Guerrero, Iván; Chávez-Velasco, Daniel; Ocaña Farfán, María del Carmen; Medina-Torres, Miguel Ángel; Romero-Sánchez, Lilian B.[et al.] (Springer Nature, 2021)
Octyltrimethylammonium tetrathiotungstate salt (ATT-C8) was synthesized and its ability to chelate copper was evaluated. The biological and toxic aspects were evaluated by in vitro and in vivo assays, using bovine aorta ... -
Synthetic collective intelligence.
(Elsevier, 2016)Intelligent systems have emerged in our biosphere in different contexts and achieving different levels of complexity. The requirement of communication in a social context has been in all cases a determinant. The human ... -
The NAC transcription factor FaRIF controls fruit ripening in strawberry
Martín-Pizarro, Carmen; Vallarino Castro, José G.; Osorio-Algar, Sonia; Meco, Victoriano; Urrutia, María; Pillet, Jeremy; Casañal, Ana; Merchante-Berg, Catharina; Amaya Saavedra, Iraida; Willmitzer, Lothar; Fernie, Alisdair R; Giovannoni, James J.; Botella-Mesa, Miguel Ángel; Valpuesta-Fernández, Victoriano; Posé-Padilla, David[et al.] (Oxford University Press, 2021-02-24)
In contrast to climacteric fruits such as tomato, the knowledge on key regulatory genes controlling the ripening of straw- berry, a nonclimacteric fruit, is still limited. NAC transcription factors (TFs) mediate different ...