Listar BMB - Artículos por título
Mostrando ítems 97-116 de 118
-
Regulatory role of microRNA in mesenteric lymph nodes after Salmonella Typhimurium infection
Claros-Díaz, Manuel Gonzalo
; Herrera‐Uribe, Juber; Zaldívar‐López, Sara; Aguilar, Carmen; Luque, Cristina; Bautista-Moreno, Rocío; Carvajal, Ana; Garrido, Juan José[et al.] (Veterinary Research, 2018)
Salmonellosis is a gastrointestinal disease caused by non‐typhoidal Salmonella serovars such as Salmonella Typhimu‐ rium. This pathology is a zoonosis, and food animals with subclinical infection constitute a vast reservoir ... -
Screening of Synergistic Interactions of Epigallocatechin-3-gallate with Antiangiogenic and Antitumor Compounds
Rodríguez-Quesada, Ana María; Medina-Torres, Miguel Ángel; García-Vilas García, Javier Alejandro (Elsevier, 2016-07)
Purpose: To screen for possible synergistic interactions of epigallocatechin-3-gallate (EGCG) with a selection of 10 anti-angiogenic or anti-tumor compounds on the survival of endothelial and tumor cells. Methods: Human ... -
Secretory Profile of Adipose-Tissue-Derived Mesenchymal Stem Cells from Cats with Calicivirus-Positive Severe Chronic Gingivostomatitis
Villatoro, Antonio J.; Martín Astorga, María del Carmen; Alcoholado Cueto, Cristina; Kazantseva, Liliya; Cárdenas García, Casimiro; Fariñas Guerrero, Fernando; Becerra-Ratia, José; Visser, Rick[et al.] (IOAP-MPDI, 2022-05-25)
The feline calicivirus (FCV) causes infections in cats all over the world and seems to be related to a broad variety of clinical presentations, such as feline chronic gingivostomatitis (FCGS), a severe oral pathology in ... -
Structural Bases for the Allergenicity of Fra a 1.02 in Strawberry Fruits.
Orozco-Navarrete, Begoña; Kaczmarska, Zuzanna; Dupeux, Florine; Garrido-Arandia, María; Pott, Delphine; Díaz-Perales, Araceli; Casañal, Ana; Márquez, José A.; Valpuesta-Fernández, Victoriano; Merchante-Berg, Catharina[et al.] (American Chemical Society, 2019-11-27)
Although strawberries are highly appreciated fruits, their intake can induce allergic reactions in atopic patients. These reactions can be due to the patient’s previous sensitization to the major birch pollen allergen Bet ... -
Sustainability in the management of scientific information
Medina-Torres, Miguel Ángel (Springer Nature, 2020-09-25)
The sustainability in the management of scientific information is becoming compromised in this new age of Big Data. Herein, I present and discuss some of the main challenges of this situation in both scientific practice ... -
Synthesis, characterization and biological evaluation of octyltrimethylammonium tetrathiotungstate
Vega-Granados, Karla; Cruz-Reyes, Juan; Horta-Marrón, José F.; Mari-Beffa, Manuel; Díaz-Rubio, Laura; Córdova-Guerrero, Iván; Chávez-Velasco, Daniel; Ocaña Farfán, María del Carmen; Medina-Torres, Miguel Ángel; Romero-Sánchez, Lilian B.[et al.] (Springer Nature, 2021)
Octyltrimethylammonium tetrathiotungstate salt (ATT-C8) was synthesized and its ability to chelate copper was evaluated. The biological and toxic aspects were evaluated by in vitro and in vivo assays, using bovine aorta ... -
Synthetic collective intelligence.
(Elsevier, 2016)Intelligent systems have emerged in our biosphere in different contexts and achieving different levels of complexity. The requirement of communication in a social context has been in all cases a determinant. The human ... -
The Marine Fungal Metabolite, AD0157, Inhibits Angiogenesis by Targeting the Akt Signaling Pathway
(MDPI, 2014-01-16)En el marco de un programa de selección de inhibidores de la angiogénesis de origen marino, se seleccionó AD0157, un metabolito fúngico de la pirrolidinediona, por sus propiedades angiosupresoras. AD0157 inhibió el crecimiento ... -
The NAC transcription factor FaRIF controls fruit ripening in strawberry
Martín-Pizarro, Carmen; Vallarino Castro, José G.; Osorio-Algar, Sonia; Meco, Victoriano; Urrutia, María; Pillet, Jeremy; Casañal, Ana; Merchante-Berg, Catharina; Amaya Saavedra, Iraida; Willmitzer, Lothar; Fernie, Alisdair R; Giovannoni, James J.; Botella-Mesa, Miguel Ángel; Valpuesta-Fernández, Victoriano; Posé-Padilla, David[et al.] (Oxford University Press, 2021-02-24)
In contrast to climacteric fruits such as tomato, the knowledge on key regulatory genes controlling the ripening of straw- berry, a nonclimacteric fruit, is still limited. NAC transcription factors (TFs) mediate different ... -
The NAC transcription factor FaRIF controls fruit ripening in strawberry.
Martín-Pizarro, Carmen; Vallarino, José G.; Osorio-Algar, Sonia; Meco, Victoriano; Urrutia, María; Pillet, Jeremy; Casañal, Ana; Merchante-Berg, Catharina; Amaya, Iraida; Willmitzer, Lothar; Fernie, Alisdair R.; Giovannoni, James J.; Botella-Mesa, Miguel Ángel; Valpuesta-Fernández, Victoriano; Posé-Padilla, David[et al.] (Oxford University Press [University Publisher], American Society of Plant Biologists [Society Publisher], 2021-02-24)
In contrast to climacteric fruits such as tomato, the knowledge on key regulatory genes controlling the ripening of strawberry, a nonclimacteric fruit, is still limited. NAC transcription factors (TFs) mediate different ... -
The noni anthraquinone damnacanthal is a multi-kinase inhibitor with potent anti-angiogenic effects
García-Vilas, Javier A.; Pino-Ángeles, Almudena; Martínez-Póveda, Beatriz Amparo; Rodríguez-Quesada, Ana María; Medina-Torres, Miguel Ángel (Elsevier, 2017-01)
The natural bioactive compound damnacanthal inhibits several tyrosine kinases. Herein, we show that -in fact- damancanthal is a multi kinase inhibitor. A docking and molecular dynamics simulation approach allows getting ... -
The Physcomitrium patens egg cell expresses several distinct epigenetic components and utilizes homologs of BONOBO genes for cell specification
(Wiley, 2022-02-17)Although land plant germ cells have received much attention, knowledge about their speci-fication is still limited. We thus identified transcripts enriched in egg cells of the bryophyte model species Physcomitrium patens, ... -
The Sponge-Derived Brominated Compound Aeroplysinin-1 Impairs the Endothelial Inflammatory Response through Inhibition of the NF-κB Pathway
Vidal-Valenzuela, Isabel; Castilla-Ruiz, Laura; Marrero-Capitán, Ana Dácil; Bravo-Ruiz, Inés; Bernal-Muñoz, Manuel; Manrique-Poyato, María Inmaculada; Rodríguez-Quesada, Ana María; Medina-Torres, Miguel Ángel; Martínez-Poveda, Beatriz Amparo; Vidal-Valenzuela[et al.] (MDPI, 2022)
Aeroplysinin-1 (Apl-1) is a brominated compound isolated from the marine sponge Aplysina aerophoba that exhibits pleiotropic bioactive effects, impairing cell growth in cancer cells, inhibiting angiogenesis in vitro and ... -
The synthetic molecule stauprimide impairs cell growth and migration in triple-negative breast cancer
Carrillo Fernández, Paloma; Bernal Muñoz, Manuel; Téllez Quijorna, Clara; Marrero Capitán, Ana Dácil; Vidal-Valenzuela, Isabel; Castilla, Laura; Caro Salazar, Carlos; Domínguez Moreno, Alejandro; García-Martín, María Luisa; Rodríguez-Quesada, Ana María; Medina-Torres, Miguel Ángel; Martínez-Póveda, Beatriz Amparo[et al.] (Elsevier, 2022-12-14)
Stauprimide, a semi-synthetic derivative of staurosporine, is known mainly for its potent differentiation-enhancing properties in embryonic stem cells. Here, we studied the effects of stauprimide in cell growth and migration ... -
Therapeutic targeting of glutaminolysis as an essential strategy to combat cancer
Mates-Sánchez, José Manuel; di Paola, Floriana J.; Campos-Sandoval, José Ángel; Mazurek, Sybille; Márquez-Gómez, Javier (Elsevier, 2020-02)
Metabolic reprogramming in cancer targets glutamine metabolism as a key mechanism to provide energy, biosynthetic precursors and redox requirements to allow the massive proliferation of tumor cells. Glutamine is also a ... -
Transcriptional stimulation of rate-limiting components of the autophagic pathway improves plant fitness.
Minina, Elena A.; Moschou, Panagiotis N.; Vetukuri, Ramesh R.; Sánchez-Vera, Victoria; Cardoso, Catarina; Liu, Qinsong; Elander, Pernilla H.; Dalman, Kerstin; Beganovic, Mirela; Lindberg, Jenny; Marmon, Sofia; Shabala, Lana; Suárez-Marín, María Fernanda; Ljung, Karin; Novak, Ondrej; Shabala, Sergei; Stymne, Sten; Hofius, Daniel; Bozhkov, Peter V.[et al.] (Journal of Experimental Botany / Oxford Academic, 2018-01-20)
Autophagy is a major catabolic process whereby autophagosomes deliver cytoplasmic content to the lytic com- partment for recycling. Autophagosome formation requires two ubiquitin-like systems conjugating Atg12 with Atg5, ... -
Transcriptome Analysis and Intraspecific Variation in Spanish Fir (Abies pinsapo Boiss.)
Ortigosa Peña, Francisco; Ávila-Sáez, Concepción; Rubio-Valverde, Lourdes; Álvarez-Garrido, Lucía; Carreira de la Fuente, José Antonio; Cañas-Pendón, Rafael Antonio; Cánovas-Ramos, Francisco Miguel[et al.] (IOAP-MPDI, 2022-08-19)
Spanish fir (Abies pinsapo Boiss.) is an endemic, endangered tree that has been scarcely investigated at the molecular level. In this work, the transcriptome of Spanish fir was assembled, providing a large catalog of ... -
Transcriptomic Insight into the Pollen Tube Growth of Olea europaea L. subsp. europaea Reveals Reprogramming and Pollen-Specific Genes Including New Transcription Factors
Claros-Díaz, Manuel Gonzalo; Bullones, Amanda; Castro, Antonio Jesús; Lima-Cabello, Elena; Fernández-Pozo, Noé; Bautista-Moreno, Rocío; Alché, Juan de Dios[et al.] (Plants, 2023)
The pollen tube is a key innovation ofland plants that is essential for successful fertilisation. Its development and growth have been profusely studied in model organisms, but in spite of the economic impact of olive ... -
TransFlow: a modular framework for assembling and assessing accurate de novo transcriptomes in non-model organisms
Claros-Díaz, Manuel Gonzalo; Seoane, Pedro; Espigares, Marina; Carmona, Rosario; Polonio, Álvaro; Quintana, Julia; Cretazzo, Enrico; Bota, Josefina; Pérez-García, Alejandro; Alché, Juan de Dios; Gómez, Luis[et al.] (BMC Bioinformatics, 2018)
The advances in high-throughput sequencing technologies are allowing more and more de novo assembling of transcriptomes from many new organisms. Some degree of automation and evaluation is required to warrant reproducibility, ... -
Translation regulation in plants: an interesting past, an exciting present and a promising future
(Wiley [Commercial Publisher] , Society for Experimental Biology [Society Publisher], 2017-05)Changes in gene expression are at the core of most biological processes, from cell differentiation to organ development, including the adaptation of the whole organism to the ever-changing environment. Although the central ...