Listar BMB - Artículos por título
Mostrando ítems 11-30 de 76
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Antioxidant responses related to temozolomide resistance in glioblastoma
(Elsevier, 2021)Glioblastoma remains one of the most challenging and devastating cancers, with only a very small proportion of patients achieving 5-year survival. The current standard of care consists of surgery, followed by radiation ... -
Antioxidant, Immunomodulatory and Potential Anticancer Capacity of Polysaccharides (Glucans) from Euglena gracilis G.A. Klebs
(IOAP-MDPI, 2022-11-10)The present study was carried out to determine the bioactivity of polysaccharides extracted from Euglena gracilis (EgPs). These were characterized by FT-IR and GC-MS. Cytotoxicity analyses (MTT) were performed on healthy ... -
Autophagy is required for strawberry fruit ripening
(Frontiers Media SA, 2021-08-27)Autophagy is a catabolic and recycling pathway that maintains cellular homeostasis under normal growth and stress conditions. Two major types of autophagy, microautophagy and macroautophagy, have been described in plants. ... -
Biomarker potential of repetitive-element transcriptome in lung cancer
(PeerJ, 2019)Since repetitive elements (REs) account for nearly 53% of the human genome, profiling its transcription after an oncogenic change might help in the search for new biomarkers. Lung cancer was selected as target since it is ... -
Bringing Light to Science Undergraduate Students: A Successful Laboratory Experiment Illustrating the Principles and Applications of Bioluminescence
(ACS Publications, 2021)Although many laboratory experiments are available to illustrate spectrophotometric or fluorometric methods, few of them introduce the use of luminometry to students. Bioluminescence, a subtype of chemiluminescence, ... -
Can a minimal replicating construct be identified as the embodiment of cancer?
(Wiley, 2014-04)Genomic instability is a hallmark of cancer. Cancer cells that exhibit abnormal chromosomes are characteristic of most advanced tumours, despite the potential threat represented by accumulated genetic damage. Carcinogenesis ... -
Can cell mortality determine division of labor in tissue organization?
(Elsevier, 2014-06)Tissue organization comes from the emergence of cell cooperation where cell homeostasis and function are per- formed as a trade-off of two excluding proliferative and differentiated cellular states. By introducing function ... -
Characterization of the activity and the mechanism of action of a new toluquinol derivative with improved potential as an antiangiogenic drug.
(Elsevier, 2022-09-30)The inhibition of sustained angiogenesis is an attractive approach for the treatment of cancer, blindness and other angiogenesis-dependent diseases. Encouraged by our previous finding that toluquinol, a methyl hydroquinone ... -
Characterizing the involvement of FaMADS9 in the regulation of strawberry fruit receptacle development
(Wiley Online Library, 2019-09-18)FaMADS9 is the strawberry (Fragaria x ananassa) gene that exhibits the highest homology to the tomato (Solanum lycopersicum) RIN gene. Transgenic lines were obtained in which FaMADS9 was silenced. The fruits of these lines ... -
A comparative study of the antiangiogenic activity of hydroxytyrosyl alkyl ethers
(2020-09-22)The phenolic compound hydroxytyrosol and its derivatives are responsible for some of the health benefits of the intake of virgin olive oil, having shown antiangiogenic properties. In this study, we explored the ... -
Comparison of the anti-angiogenic potential of hydroxytyrosol and five derivatives
(Royal Society of Chemistry, 2018)Hydroxytyrosol is a phenolic compound present in extra virgin olive oil, either in free form or as derivatives, and related to some of the health benefits described for olive oil intake. We have demonstrated previously ... -
Construction of miRNA–mRNA networks for the identification of lung cancer biomarkers in liquid biopsies
(Springer Nature, 2022-10-12)Lung cancer (LC) is the most common cause of cancer death worldwide mostly due to the low survival rate: 75% of cases are identified in advanced stages. In this study, the list of useful biomarkers to make an early diagnosis ... -
Control of tumor angiogenesis and metastasis through modulation of cell redox state
(2020-09-22)Redox reactions pervade all biology. The control of cellular redox state is essential for bioenergetics and for the proper functioning of many biological functions. This review traces a timeline of findings regarding the ... -
Copper-containing mesoporous bioactive glass promotes angiogenesis in an in vivo zebrafish model
(2018-10-19)The osteogenic and angiogenic responses of organisms to the ionic products of degradation of bioactive glasses (BGs) are being intensively investigated. The promotion of angiogenesis by copper (Cu) has been known for more ... -
Danthron, an Anthraquinone Isolated from a Marine Fungus, Is a New Inhibitor of Angiogenesis Exhibiting Interesting Antitumor and Antioxidant Properties
(MDPI, 2023-05-15)The role played by a sustained angiogenesis in cancer and other diseases stimulates the interest in the search for new antiangiogenic drugs. In this manuscript, we provide evidence that 1,8- dihydroxy-9,10-anthraquinone ... -
Development and Validation of a Multilingual Lexicon as a Key Tool for the Sensory Analyses and Consumer Tests of Blueberry and Raspberry Fruit
(IOAP-MDPI, 2023-01-28)A comprehensive lexicon is a necessary communication tool between the panel leader and panelists to describe each sensory stimulus potentially evoked by a product. In the current scientific breeding and trading scenario, ... -
Dissecting the impact of environment, season and genotype on blackcurrant fruit quality traits
(ELSEVIER, 2022-09-21)This work aims to determine the effect of genotype x environment (GxE) interaction that influence blackcurrant (Ribes nigrum) fruit quality. We applied metabolomics-driven analysis on fruits from four cultivars grown in ... -
Emerging insights into nitrogen assimilation in gymnosperms
(Springer, 2023)Gymnosperms are a heterogeneous and ancient group of seed plants that includes conifers, ginkgos, cycads and gnetophytes. Molecular studies on extant gymnosperms have been constrained by some discouraging features for ... -
Ethylene is involved in strawberry fruit ripening in an organ-specific manner
(Oxford University Press [University Publisher], Society for Experimental Biology [Society Publisher], 2013-11)The fruit of the strawberry F ananassa has traditionally been classified as non-climacteric because its ripening process is not governed by ethylene. However, previous studies have reported the timely endogenous production ... -
Ethylene signaling: simple ligand, complex regulation
(ELSEVIER, 2013-10)The hormone ethylene plays numerous roles in plant development. In the last few years the model of ethylene signaling has evolved from an initially largely linear route to a much more complex pathway with multiple feedback ...