Listar BMB - Artículos por título
Mostrando ítems 18-37 de 76
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Characterization of the activity and the mechanism of action of a new toluquinol derivative with improved potential as an antiangiogenic drug.
(Elsevier, 2022-09-30)The inhibition of sustained angiogenesis is an attractive approach for the treatment of cancer, blindness and other angiogenesis-dependent diseases. Encouraged by our previous finding that toluquinol, a methyl hydroquinone ... -
Characterizing the involvement of FaMADS9 in the regulation of strawberry fruit receptacle development
(Wiley Online Library, 2019-09-18)FaMADS9 is the strawberry (Fragaria x ananassa) gene that exhibits the highest homology to the tomato (Solanum lycopersicum) RIN gene. Transgenic lines were obtained in which FaMADS9 was silenced. The fruits of these lines ... -
A comparative study of the antiangiogenic activity of hydroxytyrosyl alkyl ethers
(2020-09-22)The phenolic compound hydroxytyrosol and its derivatives are responsible for some of the health benefits of the intake of virgin olive oil, having shown antiangiogenic properties. In this study, we explored the ... -
Comparison of the anti-angiogenic potential of hydroxytyrosol and five derivatives
(Royal Society of Chemistry, 2018)Hydroxytyrosol is a phenolic compound present in extra virgin olive oil, either in free form or as derivatives, and related to some of the health benefits described for olive oil intake. We have demonstrated previously ... -
Construction of miRNA–mRNA networks for the identification of lung cancer biomarkers in liquid biopsies
(Springer Nature, 2022-10-12)Lung cancer (LC) is the most common cause of cancer death worldwide mostly due to the low survival rate: 75% of cases are identified in advanced stages. In this study, the list of useful biomarkers to make an early diagnosis ... -
Control of tumor angiogenesis and metastasis through modulation of cell redox state
(2020-09-22)Redox reactions pervade all biology. The control of cellular redox state is essential for bioenergetics and for the proper functioning of many biological functions. This review traces a timeline of findings regarding the ... -
Copper-containing mesoporous bioactive glass promotes angiogenesis in an in vivo zebrafish model
(2018-10-19)The osteogenic and angiogenic responses of organisms to the ionic products of degradation of bioactive glasses (BGs) are being intensively investigated. The promotion of angiogenesis by copper (Cu) has been known for more ... -
Danthron, an Anthraquinone Isolated from a Marine Fungus, Is a New Inhibitor of Angiogenesis Exhibiting Interesting Antitumor and Antioxidant Properties
(MDPI, 2023-05-15)The role played by a sustained angiogenesis in cancer and other diseases stimulates the interest in the search for new antiangiogenic drugs. In this manuscript, we provide evidence that 1,8- dihydroxy-9,10-anthraquinone ... -
Development and Validation of a Multilingual Lexicon as a Key Tool for the Sensory Analyses and Consumer Tests of Blueberry and Raspberry Fruit
(IOAP-MDPI, 2023-01-28)A comprehensive lexicon is a necessary communication tool between the panel leader and panelists to describe each sensory stimulus potentially evoked by a product. In the current scientific breeding and trading scenario, ... -
Dissecting the impact of environment, season and genotype on blackcurrant fruit quality traits
(ELSEVIER, 2022-09-21)This work aims to determine the effect of genotype x environment (GxE) interaction that influence blackcurrant (Ribes nigrum) fruit quality. We applied metabolomics-driven analysis on fruits from four cultivars grown in ... -
Emerging insights into nitrogen assimilation in gymnosperms
(Springer, 2023)Gymnosperms are a heterogeneous and ancient group of seed plants that includes conifers, ginkgos, cycads and gnetophytes. Molecular studies on extant gymnosperms have been constrained by some discouraging features for ... -
Ethylene is involved in strawberry fruit ripening in an organ-specific manner
(Oxford University Press [University Publisher], Society for Experimental Biology [Society Publisher], 2013-11)The fruit of the strawberry F ananassa has traditionally been classified as non-climacteric because its ripening process is not governed by ethylene. However, previous studies have reported the timely endogenous production ... -
Ethylene signaling: simple ligand, complex regulation
(ELSEVIER, 2013-10)The hormone ethylene plays numerous roles in plant development. In the last few years the model of ethylene signaling has evolved from an initially largely linear route to a much more complex pathway with multiple feedback ... -
Exploring the ring-closing metathesis for the construction of the solomonamide macrocyclic core: identification of bioactive precursors
(2018-10-19)New synthetic strategies directed toward the novel cyclopeptides solomonamides have been explored utilizing an olefin metathesis as the key reaction. In the various strategies investigated, we worked on minimally oxidized ... -
Fishing anti(lymph)angiogenic drugs with zebrafish
(2018-10-19)Zebrafish, an amenable small teleost fish with a complex mammal-like circulatory system, is being increasingly used for drug screening and toxicity studies. It combines the biological complexity of in vivo models with a ... -
Functional Analysis of TM6 MADS-box gene in the Octoploid Strawberry by CRISPR/Cas9 directed mutagenesis
(bioRxiv, 2018-06-20)The B-class of MADS-box transcription factors has been studied in many plant species, but remain functionally uncharacterized in the Rosaceae family. APETALA3 (AP3), a member of this class, controls the identity of petals ... -
Functional Analysis of TM6 MADS-box gene in the Octoploid Strawberry by CRISPR/Cas9 directed mutagenesis
(Oxford University Press, 2019-01)The B-class of MADS-box transcription factors has been studied in many plant species, but remains functionally unchar- acterized in Rosaceae. APETALA3 (AP3), a member of this class, controls petal and stamen identities in ... -
Gene expression atlas of fruit ripening and transcriptome assembly from RNA-seq data in octoploid strawberry (Fragaria × ananassa)
(Springer Nature, 2017-10-23)RNA-seq has been used to perform global expression analysis of the achene and the receptacle at four stages of fruit ripening, and of the roots and leaves of strawberry (Fragaria × ananassa). About 967 million reads and ... -
Gene-specific translation regulation mediated by the hormone-signaling molecule EIN2
(ELSEVIER, 2015-10-22)The central role of translation in modulating gene activity has long been recognized, yet the systematic exploration of quantitative changes in translation at a genome-wide scale in response to a specific stimulus has only ... -
Generation and analysis of ESTs from strawberry (Fragaria xananassa) fruits and evaluation of their utility in genetic and molecular studies
(BMC, 2010-09-17)Cultivated strawberry is a octoploid species whose fruit is highly appreciated due to its organoleptic properties and health benefits. However, information about the role played by different hormones on these processes ...