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    •   RIUMA Principal
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      • A problem-/case-based learning approach as an useful tool for studying glycogen metabolism and its regulation 

        García-Ponce, Ángel Luis; Martínez-Poveda, Beatriz; Blanco-Lopez, Angel; Quesada, Ana R.; Suarez-Marin, Maria Fernanda; [et al.] (2020-09-23)
        Metabolism and its regulation is one of the most complex and difficult topics for students learning biochemistry. A problem-/case-based learning (PBL) approach can be useful to help biochemistry students to fulfill the ...
      • Sustainability in the management of scientific information 

        Medina, Miguel Ángel (Springer Nature, 2020-09-25)
        The sustainability in the management of scientific information is becoming compromised in this new age of Big Data. Herein, I present and discuss some of the main challenges of this situation in both scientific practice ...
      • Bringing Light to Science Undergraduate Students: A Successful Laboratory Experiment Illustrating the Principles and Applications of Bioluminescence 

        García-Ponce, Ángel Luis; Torres-Vargas, José Antonio; García-Caballero, Melissa; Medina, Miguel ángel; Blanco-López, Ángel; [et al.] (ACS Publications, 2021)
        Although many laboratory experiments are available to illustrate spectrophotometric or fluorometric methods, few of them introduce the use of luminometry to students. Bioluminescence, a subtype of chemiluminescence, ...
      • Synthesis, characterization and biological evaluation of octyltrimethylammonium tetrathiotungstate 

        Vega-Granados, Karla; Cruz-Reyes, Juan; Horta-marrón, José F.; Mari-Beffa, Manuel; Díaz-Rubio, Laura; [et al.] (Springer Nature, 2021)
        Octyltrimethylammonium tetrathiotungstate salt (ATT-C8) was synthesized and its ability to chelate copper was evaluated. The biological and toxic aspects were evaluated by in vitro and in vivo assays, using bovine aorta ...
      • Antioxidant responses related to temozolomide resistance in glioblastoma 

        Campos-Sandoval, Jose Angel; Gómez-García, María C.; Santos-Jiménez, Juan de los; Mates-Sanchez, Jose Manuel; Alonso, Francisco J.; [et al.] (Elsevier, 2021)
        Glioblastoma remains one of the most challenging and devastating cancers, with only a very small proportion of patients achieving 5-year survival. The current standard of care consists of surgery, followed by radiation ...
      • The NAC transcription factor FaRIF controls fruit ripening in strawberry 

        Martín-Pizarro, Carmen; Vallarino, José G.; Osorio-Algar, Sonia; Meco, Victoriano; Urrutia, María; [et al.] (Oxford University Press, 2021-02-24)
        In contrast to climacteric fruits such as tomato, the knowledge on key regulatory genes controlling the ripening of straw- berry, a nonclimacteric fruit, is still limited. NAC transcription factors (TFs) mediate different ...
      • Autophagy is required for strawberry fruit ripening 

        Sánchez-Sevilla, José F.; Botella-Mesa, Miguel Angel; Valpuesta-Fernandez, Victoriano; Sanchez-Vera, Victoria (Frontiers Media SA, 2021-08-27)
        Autophagy is a catabolic and recycling pathway that maintains cellular homeostasis under normal growth and stress conditions. Two major types of autophagy, microautophagy and macroautophagy, have been described in plants. ...
      • Non-targeted metabolomics characterization of Annona muricata leaf extracts with anti-angiogenic activity 

        Cárdenas, Casemiro; Torres-Vargas, José Antonio; Cárdenas Valdivia, Abel; Jurado, Nuria; Rodriguez-Quesada, Ana Maria; [et al.] (ELSEVIER, 2021-11)
        The tropical plant Annona muricata has been widely used for traditional ethnobotanic and pharmacologic applications. Extracts from different parts of this plant have been shown to have a wide range of biological activities. ...
      • Ammonium regulates the development of pine roots through hormonal crosstalk and differential expression of transcription factors in the apex 

        Ortigosa, Francisco; Lobato-Fernández, César; Shikano, Hitomi; Avila-Saez, Concepcion; Taira, Shu; [et al.] (Wiley, 2021-11-01)
        Ammonium is a prominent source of inorganic nitrogen for plant nutrition, but excessive amounts can be toxic for many species. However, most conifers are tolerant to ammonium, a relevant physiological feature of this ancient ...
      • A revised view on the evolution of glutamine synthetase isoenzymes in plants 

        Valderrama-Martín, José Miguel; Ortigosa, Francisco; Avila-Saez, Concepcion; Canovas-Ramos, Francisco Miguel; Hirel, Bertrand; [et al.] (Wiley, 2022-02)
        Glutamine synthetase (GS) is a key enzyme responsible for the incorporation of inorganic nitrogen in the form of ammonium into the amino acid glutamine. In plants, two groups of functional GS enzymes are found: eubacterial ...
      • Turning around Cycles: An Approach Based on Selected Problems/Cases to Stimulate Collaborative Learning about Krebs and His Four Metabolic Cycles 

        Medina, Miguel Ángel; García-Ponce, Ángel Luis; Blanco-Lopez, Angel; Quesada, Ana R.; Urdiales-Ruiz, Jose Luis; [et al.] (ACS, 2022-05-25)
        Metabolism is a challenging subject for bioscience students due to the intrinsic complexity of the metabolic network, as well as that of the overlapping mechanisms of metabolic regulation. Collaborative learning based on ...
      • Secretory Profile of Adipose-Tissue-Derived Mesenchymal Stem Cells from Cats with Calicivirus-Positive Severe Chronic Gingivostomatitis 

        Villatoro, Antonio J.; Martín Astorga, María del Carmen; Alcoholado Cueto, Cristina; Kazantseva, Liliya; Cardenas, Casimiro; [et al.] (IOAP-MPDI, 2022-05-25)
        The feline calicivirus (FCV) causes infections in cats all over the world and seems to be related to a broad variety of clinical presentations, such as feline chronic gingivostomatitis (FCGS), a severe oral pathology in ...
      • Network-Based Methods for Approaching Human Pathologies from a Phenotypic Point of View 

        Ranea, Juan A. G.; Richard Perkins, James; Chagoyen, Mónica; Díaz-Santiago, Elena; Pazos, Florencio (IOAP-MPDI, 2022-06-17)
        Network and systemic approaches to studying human pathologies are helping us to gain insight into the molecular mechanisms of and potential therapeutic interventions for human diseases, especially for complex diseases where ...
      • A course-based undergraduate research experience to illustrate the early stages of the drug discovery process 

        García-Caballero, Melissa; Moya-García, Aurelio; Torres-Vargas, José Antonio; García-Ponce, Ángel Luis; Rodriguez-Quesada, Ana Maria (Wiley, 2022-07-12)
        We have implemented at the University of Málaga (Spain) a new course-based undergraduate research experience (CURE) to involve undergraduate students of Science in a real-world scientific problem. Within the topic “Let's ...
      • Transcriptome Analysis and Intraspecific Variation in Spanish Fir (Abies pinsapo Boiss.) 

        Ortigosa Peña, Francisco; Avila-Saez, Concepcion; Rubio-Valverde, Lourdes; Álvarez-Garrido, Lucía; Carreira de la Fuente, José Antonio; [et al.] (IOAP-MPDI, 2022-08-19)
        Spanish fir (Abies pinsapo Boiss.) is an endemic, endangered tree that has been scarcely investigated at the molecular level. In this work, the transcriptome of Spanish fir was assembled, providing a large catalog of ...
      • Profiling the Influence of Gene Variants Related to Folate-Mediated One-Carbon Metabolism on the Outcome of In Vitro Fertilization (IVF) with Donor Oocytes in Recipients Receiving Folic Acid Fortification 

        Reyes Palomares, Arturo Lazaro; Ruiz-Galdon, Maximiliano; Liu, Kui; Reyes-Engel, Armando; Rodriguez-Wallberg, Kenny A. (IOAP-MPDI, 2022-09-25)
        Nutritional status and gene polymorphisms of one-carbon metabolism confer a well-known interaction that in pregnant women may affect embryo viability and the health of the newborn. Folate metabolism directly impacts ...
      • Antioxidant, Immunomodulatory and Potential Anticancer Capacity of Polysaccharides (Glucans) from Euglena gracilis G.A. Klebs 

        Casas Arrojo, Virginia; Arrojo Agudo, María de los Ángeles; Cárdenas García, Casimiro; Carrillo, Paloma; Pérez Manríquez, Claudia; [et al.] (IOAP-MDPI, 2022-11-10)
        The present study was carried out to determine the bioactivity of polysaccharides extracted from Euglena gracilis (EgPs). These were characterized by FT-IR and GC-MS. Cytotoxicity analyses (MTT) were performed on healthy ...
        REPOSITORIO INSTITUCIONAL UNIVERSIDAD DE MÁLAGA
        REPOSITORIO INSTITUCIONAL UNIVERSIDAD DE MÁLAGA
         

         

        REPOSITORIO INSTITUCIONAL UNIVERSIDAD DE MÁLAGA
        REPOSITORIO INSTITUCIONAL UNIVERSIDAD DE MÁLAGA