ListarBMB - Artículos por tema "Neovascularización"
Mostrando ítems 1-10 de 10
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(+)-Aeroplysinin-1 Modulates the Redox Balance of Endothelial Cells
García-Vilas García, Javier Alejandro; Martínez-Póveda, Beatriz Amparo
; Rodríguez-Quesada, Ana María; Medina-Torres, Miguel Ángel (IOAP-MPDI, 2018-09-06)
The bioactive natural compound from marine origin, (+)-aeroplysinin-1, has been shown to exhibit potent anti-inflammatory and anti-angiogenic effects. The aim of the present study was to identify new targets for ... -
Characterization of the activity and the mechanism of action of a new toluquinol derivative with improved potential as an antiangiogenic drug.
Torres-Vargas, José Antonio; Cheng-Sánchez, Iván; Martínez-Póveda, Beatriz Amparo; Medina-Torres, Miguel Ángel; Sarabia-García, Francisco Ramón; García-Caballero, Melissa; Rodríguez-Quesada, Ana María[et al.] (Elsevier, 2022-09-30)
The inhibition of sustained angiogenesis is an attractive approach for the treatment of cancer, blindness and other angiogenesis-dependent diseases. Encouraged by our previous finding that toluquinol, a methyl hydroquinone ... -
A comparative study of the antiangiogenic activity of hydroxytyrosyl alkyl ethers
Marrero Capitán, Ana Dácil; Castilla, Laura; Espartero Sánchez, José Luis; Madrona, Andrés; Rodríguez-Quesada, Ana María; Medina-Torres, Miguel Ángel; Martínez-Póveda, Beatriz Amparo[et al.] (2020-09-22)
The phenolic compound hydroxytyrosol and its derivatives are responsible for some of the health benefits of the intake of virgin olive oil, having shown antiangiogenic properties. In this study, we explored the ... -
Comparison of the anti-angiogenic potential of hydroxytyrosol and five derivatives
López-Jiménez, Auxiliadora; Gallardo, Elena; Espartero Sánchez, José Luis; Madrona, Andrés; Medina-Torres, Miguel Ángel; Rodríguez-Quesada, Ana María[et al.] (Royal Society of Chemistry, 2018)
Hydroxytyrosol is a phenolic compound present in extra virgin olive oil, either in free form or as derivatives, and related to some of the health benefits described for olive oil intake. We have demonstrated previously ... -
Control of tumor angiogenesis and metastasis through modulation of cell redox state
Serrano, José J.; Delgado-Martín, Belén; Medina-Torres, Miguel Ángel (2020-09-22)
Redox reactions pervade all biology. The control of cellular redox state is essential for bioenergetics and for the proper functioning of many biological functions. This review traces a timeline of findings regarding the ... -
Copper-containing mesoporous bioactive glass promotes angiogenesis in an in vivo zebrafish model
Romero-Sánchez, Lilian B.; Mari-Beffa, Manuel; Carrillo Fernández, Paloma; Medina-Torres, Miguel Ángel; Díaz-Cuenca, Aránzazu (2018-10-19)
The osteogenic and angiogenic responses of organisms to the ionic products of degradation of bioactive glasses (BGs) are being intensively investigated. The promotion of angiogenesis by copper (Cu) has been known for more ... -
Fishing anti(lymph)angiogenic drugs with zebrafish
García-Caballero, Melissa; Rodríguez-Quesada, Ana María; Medina-Torres, Miguel Ángel; Mari-Beffa, Manuel (2018-10-19)
Zebrafish, an amenable small teleost fish with a complex mammal-like circulatory system, is being increasingly used for drug screening and toxicity studies. It combines the biological complexity of in vivo models with a ... -
Integrating differential expression, co-expression and gene network analysis for the identification of common genes associated with tumor angiogenesis deregulation
Monterde, Beatriz; Rojano Rivera, María Elena; Córdoba Caballero, José; Seoane Zonjic, Pedro; Perkins, James Richard; Medina-Torres, Miguel Ángel; García-Ranea, Juan Antonio[et al.] (Elsevier, 2023)
Angiogenesis is essential for tumor growth and cancer metastasis. Identifying the molecular pathways involved in this process is the first step in the rational design of new therapeutic strategies to improve cancer treatment. ... -
Metabolic Reprogramming in Tumor Endothelial Cells.
(MDPI, 2022-09-21)The dynamic crosstalk between the different components of the tumor microenvironment is critical to determine cancer progression, metastatic dissemination, tumor immunity, and therapeutic responses. Angiogenesis is critical ... -
Non-targeted metabolomics characterization of Annona muricata leaf extracts with anti-angiogenic activity
Cárdenas García, Casimiro; Torres-Vargas, José Antonio; Cárdenas Valdivia, Abel; Jurado, Nuria; Rodríguez-Quesada, Ana María; García-Caballero, Melissa; Martínez-Póveda, Beatriz Amparo; Medina-Torres, Miguel Ángel[et al.] (ELSEVIER, 2021-11)
The tropical plant Annona muricata has been widely used for traditional ethnobotanic and pharmacologic applications. Extracts from different parts of this plant have been shown to have a wide range of biological activities. ...