• Influence of the microbiome on radiotherapy-induced oral mucositis and its management: A comprehensive review 

  Fernández Forné, África; García Anaya, María Jesús; Segado Guillot, Salvador José; Plaza-Andrades, Isaac; De-la-Peña-Fernández, Lourdes; Lorca Ocón, María Jesús; Lupiáñez Pérez, Yolanda; Queipo-Ortuño, María Isabel; Gómez-Millán Barrachina, Jaime[et al.] (Elsevier, 2023-07)

  Radiation-induced mucositis is the most common, debilitating and painful acute toxicity associated with active treatment in head and neck cancer area, severely affecting more than 65% of patients. Oral microbiota significantly ...

• Sucrosomial® Iron: An Updated Review of Its Clinical Efficacy for the Treatment of Iron Deficiency. 

  Gómez-Ramírez, Susana; Brilli, Elisa; Tarantino, Germano; Girelli, Domenico; Muñoz-Gómez, Manuel (MDPI, 2023-06-06)

  Iron deficiency (ID) and iron deficiency anemia (IDA) are highly prevalent worldwide. Oral iron salts, especially ferrous sulfate, are commonly used for the treatment of iron deficiency (ID). However, its use is associated ...

• Calcium Homeostasis in the Development of Resistant Breast Tumors. 

  Martin-García, Desirée; Téllez-Santana, Teresa; Redondo-Bautista, Maximino; García Aranda, Marilina (MDPI, 2023-05-23)

  Cancer is one of the main health problems worldwide. Only in 2020, this disease caused more than 19 million new cases and almost 10 million deaths, with breast cancer being the most diagnosed worldwide. Today, despite ...

• Prenatal Predictors of Neurobehavioral Outcome in Children with Fetal Growth Restriction at 6 Years of Age: A Retrospective Cohort Study. 

  Benítez-Marín, María José; Blasco Alonso, Marta; González-Mesa, Ernesto Santiago (MDPI, 2023-06-01)

  Background: Fetal growth restriction (FGR) increases the risk of adverse neurodevelopmental outcomes, especially in preterm newborns. This study aims to describe the behavioral results of FGR at 6 years of age and to ...

• Perinatal and maternal outcomes according to the accurate term antepartum ultrasound estimation of extreme fetal weights 

  Mozas-Moreno, Juan; Sánchez-Fernández, Mariola; González-Mesa, Ernesto Santiago; Olmedo-Requena, Rocío; Amezcua-Prieto, Carmen; Jiménez-Moleon, José Juan[et al.] (MDPI, 2023-04-20)

  Background: The accuracy of ultrasound estimation of fetal weight (EFW) at term may be useful in addressing obstetric complications since birth weight (BW) is a parameter that represents an important prognostic factor for ...

• Características estructurales del hueso trabecular de cabeza femoral: diferencias entre hueso fracturado y hueso no fracturado. 

  Sánchez-Siles, Juan Manuel (UMA Editorial, 2023)

  Las fracturas de cadera en el anciano se deben a caídas en pacientes que sufren osteopenia y, por tanto, fragilidad ósea. La osteoporosis, es una enfermedad silente cuya primera manifestación clínica suele ser una fractura. ...

• Neurodesarrollo en niños con restricción del crecimiento intrauterino 

  Benítez-Marín, María José (UMA Editorial, 2023-03-03)

  La principal meta de este estudio ha sido evaluar el neurodesarrollo a los 6 años en un grupo de niños con restricción del crecimiento intrauterino (RCIU), en la esfera de comportamiento, inteligencia e hitos del desarrollo. ...

• Mendelian Randomisation Confirms the Role of Y-Chromosome Loss in Alzheimer’s Disease Aetiopathogenesis in Men 

  García-González, Pablo; Rojas, Itziar de; Moreno-Grau, Sonia; Montrreal, Laura; Puerta, Raquel; Alarcón-Martín, Emilio; Quintela, Inés; Orellana, Adela; Andrade, Victor; Martino Adami, Pamela V.; Heilmann-Heimbach, Stefanie; Gomez-Garre, Pilar; Periñán, María Teresa; Alvarez, Ignacio; Díez-Fairen, Mónica; Nuñez Llaves, Raul; Olivé Roig, Claudia; Garcia-Ribas, Guillermo; Menéndez-González, Manuel; Martínez, Carmen; Aguilar, Miquel; Buongiorno, Mariateresa; Franco-Macías, Emilio; Saez, Maria Eugenia; Cano, Amanda; Bullido Gómez-Heras, Maria Jesús; Real-Navarrete, Luis Miguel; Rodríguez-Rodríguez, Eloy; Royo-Sánchez-Palencia, José Luis; Álvarez, Victoria; Pastor, Pau; Piñol-Ripoll, Gerard; Mir, Pablo; Calero Lara, Miguel; Medina Padilla, Miguel; Sánchez-Juan, Pascual; Carracedo Álvarez, Ángel María; Valero, Sergi; Hernandez, Isabel; Tàrraga, Lluis; Ramirez, Alfredo; Boada, Mercé; Ruiz Laza, Agustín[et al.] (IOAP-MDPI, 2023-01-04)

  Mosaic loss of chromosome Y (mLOY) is a common ageing-related somatic event and has been previously associated with Alzheimer’s disease (AD). However, mLOY estimation from genotype microarray data only reflects the mLOY ...

• Development of a Novel NGS Methodology for Ultrasensitive Circulating Tumor DNA Detection as a Tool for Early-Stage Breast Cancer Diagnosis 

  Jiménez-Rodríguez, Begoña; Alba-Bernal, Alfonso; López-López, Esperanza; Quirós-Ortega, María Elena; Carbajosa, Guillermo; Garrido-Aranda, Alicia; Álvarez-Pérez, Martina; Godoy-Ortiz, Ana; Queipo-Ortuño, María Isabel; Vicioso-Recio, Luis Prudencio; Díaz-Córdoba, Gema; Roldán-Díaz, María Dunia; Velasco-Suelto, Jesús; Hernando Melia, Cristina; Bermejo, Begoña; Julve-Parreño, Ana; Lluch, Ana; Pascual, Javier; Comino-Méndez, Iñaki; Alba-Conejo, Emilio[et al.] (IOAP-MDPI, 2022-12-21)

  Breast cancer (BC) is the most prevalent cancer in women. While usually detected when localized, invasive procedures are still required for diagnosis. Herein, we developed a novel ultrasensitive pipeline to detect circulating ...

• Detection of Relevant Heavy Metal Concentrations in Human Placental Tissue: Relationship between the Concentrations of Hg, As, Pb and Cd and the Diet of the Pregnant Woman 

  Molina-Mesa, Soledad; Martínez-Cendán, Juan Pedro; Moyano-Rubiales, Daniel; Cubillas-Rodríguez, Inmaculada; Molina-García, Jorge Antonio; González-Mesa, Ernesto Santiago[et al.] (IOAP-MPDI, 2022-11-09)

  Heavy metals can cross the placental barrier and reach the fetal compartment, threatening fetal development. Pregnant women can acquire these through food, drinking water, toxic habits or simply by breathing polluted air. ...

• Prevalence of Anxiety and Depression Symptoms and Their Relationship with Nutritional Status and Mortality in Patients with Colorectal Cancer 

  Soria-Utrilla, Virginia; González-Poveda, Iván; Mera-Velasco, Santiago; Porras, Nuria; Toval-Mata, José Antonio; García-Olivares, María; Ruiz López, Manuel; Gonzalo-Marín, Montserrat; Carrasco-Campos, Joaquín; Tapia Guerrero, María José; Santoyo-Santoyo, Julio; Olveira-Fuster, Gabriel María[et al.] (IOAP-MPDI, 2022-10-19)

  Background: Anxiety and depression are common in patients with cancer. The aim of this study is to determine the prevalence of anxiety and depression symptoms in colorectal cancer (CRC) patients awaiting elective surgery ...

• d-Pinitol promotes tau dephosphorylation through a cyclin-dependent kinase 5 regulation mechanism: A new potential approach for tauopathies? 

  Medina-Vera, Dina; Navarro, Juan Antonio; Rivera, Patricia (WILEY, 2022-06-27)

  Background and Purpose Recent evidence links brain insulin resistance with neurodegenerative diseases, where hyperphosphorylated tau protein contributes to neuronal cell death. In the present study, we aimed to evaluate ...

• Role of SODC protein in antineoplastic drug resistance 

  Alamilla Presuel, Juan Carlos; González Vidal, Alejandro; Ruiz González, Óscar M.; Burgos-Molina, Antonio Manuel; Ruiz-Gómez, Miguel José (Aseica, 2022)

  Cells need homeostasis to survive, therefore, they use the different pathways available to obtain it. The SODC protein overexpression, which is implicated in this process, suggests that could be implicated in the process ...

• Proteins involved in carbon metabolism induce bleomycin resistance 

  Burgos-Molina, Antonio Manuel; Alamilla Presuel, Juan Carlos; Mercado-Sáenz, Silvia; González Vidal, Alejandro; Ruiz González, Óscar M.; Ruiz-Gómez, Miguel José[et al.] (Aseica, 2022)

  S. cerevisiae acquires bleomycin resistance after a long-term exposure to this drug which causes overexpression of TPIS protein. It could be involved in the resistance process. For this reason, it could be good candidates ...

• Metabolism is altered in the process of drug resistance acquisition 

  Burgos-Molina, Antonio Manuel; Alamilla Presuel, Juan Carlos; González Vidal, Alejandro; Ruiz-Gómez, Miguel José (Aseica, 2022)

  Cells need energy to survive, therefore, they increase the different pathways available to obtain it. This suggests that the cell, due to the cytotoxicity of bleomycin, increases the routes to obtain energy. For this reason, ...

• Acquisition resistance to bleomycin deregulates HSP77 and HSP60 proteins in response to stress 

  Burgos-Molina, Antonio Manuel; Alamilla Presuel, Juan Carlos; Mercado-Sáenz, Silvia; González Vidal, Alejandro; Ruiz-Gómez, Miguel José (Aseica, 2022)

  The HSP77 and HSP60 protein overexpression is implicated in bleomycin resistance. The resistant adquisition to antineoplastic drugs deregulate proteins involved in response to stress factors.

• Clinical metagenomic analysis and Cancer 

  Burgos-Molina, Antonio Manuel; Mercado-Sáenz, Silvia; Morales Moreno, Francisco; González Vidal, Alejandro; Ruiz-Gómez, Miguel José (Aseica, 2022)

  After seven years of periodic controls by the SEIMC (Spanish Society of Infectious Diseases and Clinical Microbiology), it can be affirmed that the analysis is capable of detecting microorganisms in any type of sample ...

• Analysis of Immunotherapy in Triple negative breast cancer 

  Burgos-Molina, Antonio Manuel; Alamilla Presuel, Juan Carlos; González Vidal, Alejandro; Ruiz-Gómez, Miguel José (Aseica, 2022)

  TNBC cancer is complicated, most is about PD-L1 mechanism. Too many kinds of immunotherapy have been developed to treat TNCB. Nowadays, is complicated a fast and 100% accurate treatment for TNBC, because of cancer complications ...

• Analysis of Immunotherapy in Lung cancer 

  Burgos-Molina, Antonio Manuel; Alamilla Presuel, Juan Carlos; González Vidal, Alejandro; Ruiz-Gómez, Miguel José (Aseica, 2022)

  There are many ways of immunotherapy for lung cancer, and that includes the use of drugs, molecular treatment, and even the combination with radiotherapy. But also, it’s important to investigate in the future the adverse ...

• Analysis of Immunotherapy in hepatocellular carcinoma 

  Burgos-Molina, Antonio Manuel; Alamilla Presuel, Juan Carlos; González Vidal, Alejandro; Ruiz-Gómez, Miguel José (Aseica, 2022)

  One reason immunotherapy is important for Hepatocellular carcinoma, it’s because there are many immune cells in that organ. Because HCC is very aggressive, immunotherapy must be applied correctly. There are a lot of ...

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