ListarFarmacología y Pediatría - (FP) por tema "DILI"
Mostrando ítems 1-9 de 9
-
A revised electronic version of RUCAM for the diagnosis of DILI
Hayashi, Paul H.; Lucena-González, María Isabel
; Fontana, Robert J.; Bjornsson, Einar S.; Aithal, Guruprasad P.; Barnhart, Huiman; González-Jiménez, Andrés; Yang, Qinghong; Gu, Jiezhun; Andrade-Bellido, Raúl Jesús; Hoofnagle, Jay H.[et al.] (Wiley, 2022)
Background and Aims: Roussel Uclaf Causality Assessment Method (RUCAM) for DILI has been hindered by subjectivity and poor reliability. We sought to improve the RUCAM using data from the Drug-Induced Liver Injury Network ... -
Análisis de las propiedades farmacológicas, los factores del huésped y su interacción en el desarrollo de hepatotoxicidad asociada a fármacos
(UMA Editorial, 2017)INTRODUCTION Drug-induced liver injury is an important concern in public health. In addition, it is one of the most common adverse events that cause lack of drug approval, drug withdrawals, and post-marketing regulatory ... -
Biomarkers of idiosyncratic drug-induced liver injury (DILI) - a systematic review
(Taylor & Francis, 2021-11-15)Introduction: Idiosyncratic drug-induced liver injury (DILI) is an unpredictable event, and there are no specific biomarkers that can distinguish DILI from alternative explanations or predict its clinical outcomes. Areas ... -
Comprehensive analysis and insights gained from long-term experience of the Spanish DILI Registry
Stephens, Camilla; Robles-Díaz, María Mercedes; Medina-Cáliz, Inmaculada; García-Cortés, Miren; Ortega-Alonso, Aida; Sanabria-Cabrera, Judith Adriana; González-Jiménez, Andrés; Alvarez-Alvarez, Ismael; Slim, Mahmoud; Jiménez-Pérez, Miguel; González-Grande, Rocío; Fernández, M. Carmen; Casado, Marta; Soriano, German; Roman, Eva; Hallal, Hacibe; Romero-Gomez, Manuel; Castiella, Agustin; Conde, Isabel; Prieto, Martin; Moreno-Planas, José María; Giraldez, Alvaro; Moreno-Sanfiel, J Miguel; Kaplowitz, Neil; Lucena-González, María Isabel; Andrade-Bellido, Raúl Jesús[et al.] (Elsevier, 2021-02-01)
Background & aims: Prospective drug-induced liver injury (DILI) registries are important sources of information on idiosyncratic DILI. We aimed to present a comprehensive analysis of 843 patients with DILI enrolled into ... -
Hepatic safety of atypical antipsychotics: current evidence and future directions
Slim, Mahmoud; Medina-Cáliz, Inmaculada; González-Jiménez, Andrés; Cabello-Porras, María Rosario; Mayoral Cleries, Fermín; Lucena-González, María Isabel; Andrade-Bellido, Raúl Jesús[et al.] (Springer, ADIS INT LTD, 2016-10)
The newer atypical antipsychotic agents (AAPs) represent an attractive therapeutic option for a wide range of psychotic disorders, including schizophrenia and bipolar mania, because of the reduced risk of disabling ... -
Infección aguda por el virus de la hepatitis E en pacientes con sospecha de daño hepático tóxico en el Spanish DILI Registry
Sanabria-Cabrera, Judith Adriana (UMA Editorial, 2020-09-30)
Antecedentes y objetivos: el daño hepático inducido por fármacos también denominado DILI (Drug Induced Liver Injury), se presenta con un amplio espectro fenotípico que requiere un diagnóstico diferencial extenso. El virus ... -
Lymphocyte Profile and Immune Checkpoint Expression in Drug-Induced Liver Injury: An Immunophenotyping Study
Cueto-Sánchez, Alejandro; Niu, Hao; Del Campo-Herrera, Enrique; Robles-Díaz, María Mercedes; Sanabria-Cabrera, Judith Adriana; Ortega-Alonso, Aida; García-Cortés, Miren; González-Grande, Rocío; Jiménez-Pérez, Miguel; Ruiz-Cabello, Francisco; Andrade-Bellido, Raúl Jesús; Lucena-González, María Isabel[et al.] (Wiley, 2021-09-20)
The identification of specific HLA risk alleles in drug-induced liver injury (DILI) points toward an important role of the adaptive immune system in DILI development. In this study, we aimed to corroborate the role of an ... -
Nomenclature, diagnosis and management of drug-induced autoimmune-like hepatitis (DI-ALH): An expert opinion meeting report
Andrade-Bellido, Raúl Jesús; Aithal, Guruprasad P.; De Boer, Ynto S.; Liberal, Rodrigo; Gerbes, Alexander L; Regev, Arie; Terziroli Beretta-Piccoli, Benedetta; Schramm, Christoph; Kleiner, David E.; De Martin, Eleonora; Kullak-Ublick, Gerd A; Stirnimann, Guido; Devarbhavi, Harshad; Vierling, John M.; Manns, Michael P.; Sebode, Marcial; Londoño, María Carlota; Avigan, Mark; Robles-Díaz, María Mercedes; García-Cortés, Miren; Atallah, Edmond; Heneghan, Michael; Chalasani, Naga; Trivedi, Palak J.; Hayashi, Paul H.; Taubert, Richard; Fontana, Robert J.; Weber, Sabine; Oo, Ye Htun; Zen, Yoh; Licata, Anna; Lucena-González, María Isabel; Mieli-Vergani, Giorgina; Vergani, Diego; Bjornsson, Einar S.[et al.] (Elsevier, 2023)
Drug-induced liver injury (DILI) can mimic almost all other liver disorders. A phenotype increasingly ascribed to drugs is autoimmune-like hepatitis (ALH). This article summarises the major topics discussed at a joint ... -
Oxidative Stress in Drug-Induced Liver Injury (DILI): From Mechanisms to Biomarkers for Use in Clinical Practice
Villanueva-Paz, Marina; Morán, Laura; López-Alcántara, Nuria; Freixo, Cristiana; Andrade-Bellido, Raúl Jesús; Lucena-González, María Isabel; Cubero, Francisco Javier[et al.] (MDPI, 2021-03-05)
Idiosyncratic drug-induced liver injury (DILI) is a type of hepatic injury caused by an uncommon drug adverse reaction that can develop to conditions spanning from asymptomatic liver laboratoryabnormalitiestoacuteliverfa ...