ListarFarmacología y Pediatría - (FP) por tema "gene variants"
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Interferon regulatory factor 5 (IRF5) gene variants are associated with multiple sclerosis in three distinct populations
Kristjansdottir, G; Sandling, JK; Bonetti, A; Roos, IM; Milani, L; Wang, C; Gustafsdottir, SM; Sigurdsson, S; Lundmark, A; Tienari, PJ; Koivisto, K; Elovaara, I; Pirttilä, T; Reunanen, M; Peltonen, L; Saarela, J; Hillert, J; Olsson, T; Landegren, U; Alcina, Antonio; Fernández Fernández, Óscar; Leyva-Fernández, Laura
; Guerrero, Miguel; Lucas, Miguel; Izquierdo, Guillermo; Matesanz, Fuencisla; Syvänen, A-C[et al.] (BMJ, 2008)
Background: IRF5 is a transcription factor involved both in the type I interferon and the toll-like receptor signalling pathways. Previously, IRF5 has been found to be associated with systemic lupus erythematosus, rheumatoid ...