Listar FP - Artículos por título
Mostrando ítems 75-94 de 104
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Papel de la radioterapia en los estadios iniciales del cáncer de cabeza y cuello
(Arán Ediciones, 2016)Los tumores precoces de cabeza y cuello tienen en general un buen pronóstico con un tratamiento adecuado. La radioterapia y cirugía son los dos pilares básicos del tratamiento, con resultados similares en cuanto a control ... -
Phase angle as a marker of outcome in hospitalized pediatric patients. A systematic review of the evidence (GRADE) with meta-analysis.
Fernández-Jiménez, Rocío; Martin‐Masot, Rafael; Cornejo Pareja, Isabel María; Vegas-Aguilar, Isabel M.; Herrador-López, Marta; Tinahones-Madueño, Francisco José
; Navas-López, Víctor Manuel; Bellido-Guerrero, Diego; García-Almeida, José Manuel[et al.] (Elsevier, 2023)
Phase angle (PhA) is a valuable tool for evaluating the nutritional and inflammatory status, which can accompany acute and severe disorders. PhA is a cellular health biomarker, whose value is particularly substantial due ... -
Physical Activity Levels, Eating Habits, and Well-Being Measures in Students of Healthcare Degrees in the Second Year of the COVID-19 Pandemic
(MDPI, 2023)The aim of this study was to analyse the physical activity, eating habits, self-perceived well-being, and toxic habits, as well as the perceived changes of these habits with respect to the pre-pandemic period, in a population ... -
Potential benefit and lack of serious risk from corticosteroids in drug-induced liver injury: an international, multicentre, propensity score-matched analysis
Niu, Hao; Ma, Jiayi; Medina-Cáliz, Inmaculada; Robles-Díaz, María Mercedes; Bonilla-Toyos, Elvira; Ghabril, Marwan; Lucena-González, María Isabel; Alvarez-Alvarez, Ismael; Andrade-Bellido, Raúl Jesús[et al.] (Wiley, 2022-12-22)
Background: The use of corticosteroids to treat patients with idiosyncratic drug-induced liver injury (DILI) relies on empirical clinical decisions. Aim: To investigate the relationship between corticosteroids and ... -
Potential probiotic salami with dietary fiber modulates metabolism and gut microbiota in a human intervention study.
(Elsevier, 2020)A human intervention in 24 healthy volunteers was performed to test the potential health benefits of a fermented salami with a probiotic Lactobacillus rhamnosus HN001 and added citrus fiber. Anthropometric measurements and ... -
Preclinical models of idiosyncratic drug-induced liver injury (iDILI): Moving towards prediction
Segovia-Zafra, Antonio; Di Zeo-Sánchez, Daniel Enrique; López-Gómez, Carlos; Pérez-Valdés, Zeus; García-Fuentes, Eduardo; Andrade-Bellido, Raúl Jesús; Lucena-González, María Isabel; Villanueva-Paz, Marina[et al.] (Elsevier, 2021-12)
Idiosyncratic drug-induced liver injury (iDILI) encompasses the unexpected harms that pre- scription and non-prescription drugs, herbal and dietary supplements can cause to the liver. iDILI remains a major public health ... -
Prevention and management of idiosyncratic drug-induced liver injury: Systematic review and meta-analysis of randomised clinical trials
Niu, Hao; Sanabria-Cabrera, Judith Adriana; Alvarez-Alvarez, Ismael; Robles-Díaz, María Mercedes; Stankeviciute, Simona; Aithal, Guruprasad P.; Bjornsson, Einar S.; Andrade-Bellido, Raúl Jesús; Lucena-González, María Isabel; Sanabria-Cabrera, Judith Adriana[et al.] (Elsevier, 2021-02)
Conducting randomised clinical trials (RCTs) in idiosyncratic drug-induced liver injury (DILI) is challenging. This systematic review aims to summarise the design and findings of RCTs in the prevention and management of ... -
Prior drug allergies are associated with worse outcome in patients with idiosyncratic drug-induced liver injury: A machine learning approach for risk stratification
Niu, Hao; Solis-Muñoz, Pablo; García-Cortés, Miren; Sanabria-Cabrera, Judith Adriana; Robles-Díaz, María Mercedes; Romero-Flores, Rocío; Bonilla-Toyos, Elvira; Ortega-Alonso, Aida; Pinazo-Bandera, José M.; Cabello-Porras, María Rosario; Bessone, Fernando; Hernandez, Nelia; Lucena-González, María Isabel; Andrade-Bellido, Raúl Jesús; Medina-Cáliz, Inmaculada; Alvarez-Alvarez, Ismael[et al.] (Elsevier, 2023-12-08)
The impact of prior drug allergies (PDA) on the clinical features and outcomes of patients who develop idiosyncratic drug-induced liver injury (DILI) is largely unknown. We aimed to assess the clinical presentation and ... -
Proactive monitoring of anti-TNF agents improves follow-up of paediatric patients with Crohn disease
(Elsevier, 2023)Introduction and aims: The incidence of paediatric inflammatory bowel disease has increased in recent decades. The aim of the present study was to evaluate the role of proactive and serial monitoring of tumour necrosis ... -
Profile of herbal and dietary supplements induced liver injury in Latin America: A systematic review of published reports
Santos, Genario; Gasca, Jessica; Parana, Raymundo; Nunes, Vinicius; Schinnoni, Maria; Medina-Cáliz, Inmaculada; Cabello-Porras, María Rosario; Lucena-González, María Isabel; Andrade-Bellido, Raúl Jesús[et al.] (WILEY, 2020-06)
Hepatotoxicity related to HDS is a growing global health issue. We have undertaken a systematic review of published case reports and case series from LA from 1976 to 2020 to describe the clinical features of HDS related ... -
Protein tyrosine phosphatase gene (PTPN22) polymorphism in multiple sclerosis.
Matesanz, Fuencisla; Rueda, Blanca; Orozco, Gisela; Fernández-Fernández, Óscar; Leyva-Fernández, Laura; Alcina, Antonio; Martín-Ibáñez, Javier[et al.] (Springer, 2005-03-17)
Alterations in the signalling pathway that regulate T-cell tyrosine phosphorylation play an important role in MS. Tyrosine phosphorylation is regulated by the equal and balanced action of protein tyrosine kinases and protein ... -
Public healthcare costs associated with long-term exposure to mixtures of persistent organic pollutants in two areas of Southern Spain: A longitudinal analysis.
Perez-Carrascosa, Francisco M; Barrios-Rodríguez, Rocío; Gómez-Peña, Celia; Salcedo-Bellido, Inmaculada; Velasco-García, Mª Eugenia; Jimenez Moleon, Jose Juan; García-Ruiz, Antonio J.; Navarro-Espigares, José Luis; Requena, Pilar; Muñoz-Sánchez, Carmen; Arrebola, Juan Pedro[et al.] (Elsevier, 2022-06-03)
Objective: To longitudinally explore public healthcare costs associated with long-term exposure to a mixture of 8 POPs in a cohort of residents of two areas of Granada Province, Southern Spain. Methods: Longitudinal study ... -
Real‑life cost‑effectiveness of benralizumab in patients with severe asthma.
Padilla‑Galo, A.; García-Ruiz, Antonio J.; Levy Abitbol, R. Ch.; Olveira-Fuster, Casilda; Rivas‑Ruiz, F; García-Agua-Soler, Nuria; Pérez Morales, Marcel; Valencia Azcona, B.; Tortajada‑Goitia, B.; Moya‑Carmona, Isabel; Levy‑Naon, Alberto[et al.] (BMC, 2021-05-27)
The aim of this study was to evaluate clinical outcomes and healthcare expenditure after incorporating benralizumab into the standard treatment of refractory eosinophilic asthma. Methods: This was a cross-sectional ... -
Roadmap to DILI research in Europe. A proposal from COST action ProEuroDILINet
Lucena-González, María Isabel; Villanueva-Paz, Marina; Alvarez-Alvarez, Ismael; Aithal, Guruprasad P.; Bjornsson, Einar S.; Cakan-Akdogan, G.; Cubero, Francisco Javier; Esteves, Freddy; Falcón-Pérez, Juan Manuel; Fromenty, B.; Garcia-Ruiz, C.; Grove, J.I.; Konu, O.; Kranendonk, M.; Kullak-Ublick, Gerd A; Miranda, J.P.; Remesal-Doblado, A.; Sancho-Bru, P.; Nelson, L.; Andrade-Bellido, Raúl Jesús; Fernandez-Checa, J.C.[et al.] (Elsevier, 2023-12-28)
In the current article the aims for a constructive way forward in Drug-Induced Liver Injury (DILI) are to highlight the most important priorities in research and clinical science, therefore supporting a more informed, ... -
Role of chemical structures and the 1331T>C bile salt export pump polymorphism in idiosyncratic drug-induced liver injury
Ulzurrun, Eugenia; Stephens, Camilla; Crespo, Esperanza; Ruiz-Cabello, Francisco; Ruiz-Nuñez, Julia; Saenz-López, Pablo; Moreno-Herrera, Inmaculada; Robles-Díaz, María Mercedes; Hallal, Hacibe; Moreno-Planas, José María; Cabello-Porras, María Rosario; Lucena-González, María Isabel; Andrade-Bellido, Raúl Jesús[et al.] (WILEY, 2013-04)
Background & aims: Several pharmaceutical compounds have been shown to exert inhibitory effects on the bile salt export pump (BSEP) encoded by the ABCB11 gene. We analysed the combined effect on drug-induced liver injury ... -
Serious liver injury induced by Nimesulide: an international collaboration study reporting 57 cases
Bessone, Fernando; Hernandez, Nelia; Mendizabal, Manuel; Ridruejo, Ezequiel; Gualano, Gisela; Fassio, Eduardo; Peralta, Mirta; Fainboim, Hugo; Anders, Margarita; Tanno, Hugo; Tanno, Federico; Parana, Raymundo; Medina-Cáliz, Inmaculada; Robles-Díaz, María Mercedes; Alvarez-Alvarez, Ismael; Niu, Hao; Stephens, Camilla; Colombato, Luis; Arrese, Marco; Reggiardo, Maria Virginia; Ono, Suzane Kioko; Carrilho, Flair; Lucena-González, María Isabel; Andrade-Bellido, Raúl Jesús[et al.] (Springer, 2021-03-24)
Nimesulide is a non-steroidal anti-inflammatory drug still marketed in many countries. We aim to analyze the clinical phenotype, outcome, and histological features of nimesulide-induced liver injury (nimesulide-DILI). We ... -
Sirolimus for the Treatment of Juvenile Polyposis in Childhood
(Wolters Kluwer Health, 2021)Juvenile polyposis syndrome (JPS) is a rare disease with an autosomal dominant inheritance pattern characterized by the development of multiple hamartomatous polyps in the gastrointestinal tract. The most frequent signs ... -
Spanish Pediatric Inflammatory Bowel Disease Diagnostic Delay Registry: SPIDER Study From Sociedad Española de Gastroenterología, Hepatología y Nutrición Pediátrica
(2020-10-15)Background and Aims: Diagnostic delay (DD) is especially relevant in children with inflammatory bowel disease, leading to potential complications. We examined the intervals and factors for DD in the pediatric population ... -
Spanish Pediatricians' Positions Regarding Prevention, Diagnosis, Nutritional Management, and Challenges in Cow's Milk Protein Allergy
(MDPI (Nutrients), 2023)Management of cow’s milk protein allergy (CMPA) can vary depending on the experience and area of expertise of the clinician responsible for the patient’s follow-up, which may or may not align with the recently published ... -
Study of binding and neutralising antibodies to interferon-β in two groups of relapsing-remitting multiple sclerosis patients.
Fernández Fernández, Óscar; Mayorga Mayorga, Cristobalina; Luque, Gloria; Guerrero, Miguel; Guerrero, Rocío; Leyva-Fernández, Laura; León-Martín, Antonio; Blanca, Miguel[et al.] (Springer Nature, 2001)
Interferon (IFN)-β is generally considered an effective treatment for multiple sclerosis (MS); however, some patients do not respond to this therapy, possibly due to the production of neutralising antibodies (NAB) which ...